Numerical and One Dimensional Modeling of Cardiovascular System Along with Lumped Parameter Modeling of the Heart

Salehi, Sarah | 2013

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  1. Type of Document: M.Sc. Thesis
  2. Language: Farsi
  3. Document No: 44710 (08)
  4. University: Sharif University of Technology
  5. Department: Mechanical Engineering
  6. Advisor(s): Firoozabadi, Bahar; Saidi, Mohammad Saeed
  7. Abstract:
  8. Cardiovascular diseases are major causes of morbidity and mortality in the world. In order to prevent or reduce these diseases, engineers and scientists are concerned to find solutions. In this way, it is important to know about the blood flow and its changes in various diseases. By using simulation methods, diagnosis can be very easier. In this study, a system of arterial tree consisting of 93 systemic arteries along with 7 pulmonary arteries is considered. In other words, this model contains 100 systemic and pulmonary arteries that encompass central and peripheral arteries. Other parts of this model are cerebral vasculature and coronary arteries. Cerebral arteries, also called circle of Willis, are made up of 18 arteries and coronary arterial tree contains 16 arteries. This arterial tree and lumped parameter model of the heart form a complete set of cardiovascular model that contains systemic and pulmonary arteries along with the heart. In this work, the geometry of the arterial network is one dimensional. Governing equations are continuity, momentum and state equations of blood flow that are solved numerically by the finite volume method. The heart is also coupled to this network by using lumped parameter model. By applying appropriate boundary conditions, pressure and blood flow rate in the arteries are obtained. Moreover, internal carotid artery stenosis is modeled and the risk of stroke is calculated. Finally, respiration, aging effect and abdominal aorta aneurysm are modeled and their effect on blood flow rate and pressure profiles on other arteries are examined
  9. Keywords:
  10. Coronary Arteries ; Cardiovascular System ; Heart Lumped Parameter Model ; Willis Circle ; Structured Tree

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