Chronic wounds are among the serious injuries which have called the attention of scientists to invest in an effort to fabricate temporary skin grafts and wound dressing materials. One of the widely acceptable solutions to this obstacle is to design a bioactive scaffold capable of regenerating tissue as well as delivering active agents to the site specific area. To this end, natural biopolymers are considered as suitable candidates to be employed in regenerative medicine due to their excellent biocompatibility. In addition, nanoparticles possess special properties such as the ability in sequestering the drug release which make them promising candidates in the fabrication of the...