A Multiscale Moving Boundary Model For Cancer Invasion, M.Sc. Thesis Sharif University of Technology ; Fotouhi Firoozabad, Morteza (Supervisor)
Abstract
Cancer invasion of tissue is a key aspect of the growth and spread of cancer and is crucial in the process of metastatic spread i.e. the growth of secondary cancers. Invasion consists in cancer cells secreting various matrix degrading enzymes (MDEs) which destroy the surronding tissue or extracellular matrix (ECM). Through a combination of proliferation and migration, the cancer cells then actively spread locally into the surrounding tissue. Thus processes occuring at the level of individual cells eventually give rise to processes occuring at the tissue level. In this thesis we introduce a new type of multiscale model describing the process of cancer invasion of tissue.Our multiscale model...
Cataloging briefA Multiscale Moving Boundary Model For Cancer Invasion, M.Sc. Thesis Sharif University of Technology ; Fotouhi Firoozabad, Morteza (Supervisor)
Abstract
Cancer invasion of tissue is a key aspect of the growth and spread of cancer and is crucial in the process of metastatic spread i.e. the growth of secondary cancers. Invasion consists in cancer cells secreting various matrix degrading enzymes (MDEs) which destroy the surronding tissue or extracellular matrix (ECM). Through a combination of proliferation and migration, the cancer cells then actively spread locally into the surrounding tissue. Thus processes occuring at the level of individual cells eventually give rise to processes occuring at the tissue level. In this thesis we introduce a new type of multiscale model describing the process of cancer invasion of tissue.Our multiscale model...
Find in contentBookmark |
|