An efficient glucose-based ligand for Heck and Suzuki coupling reactions in aqueous media

Bagherzadeh, M ; Sharif University of Technology

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  1. Type of Document: Article
  2. DOI: 10.1007/s13738-013-0316-3
  3. Abstract:
  4. The glucose-based ligand, N-salicylidene-d-glucosamine (Sal-d-glsmN), was readily obtained by reaction of salicylaldehyde (Hsal) with the d-glucosamine hydrochloride. Ligand Sal-d-glsmN was found to be an efficient ligand in the palladium-catalyzed Suzuki and Heck C-C coupling reactions in aqueous medium under aerobic condition. It was found that the use of Sal-d-glsmN/Pd(OAc) 2 system as a catalyst, aryl halides undergo Suzuki and Heck cross-couplings, respectively, with arylboronic acids and olefins to give the desired products in moderate to excellent yields
  5. Keywords:
  6. C-C coupling ; Heck reaction ; Homogeneous catalysis ; Suzuki reaction
  7. Source: Journal of the Iranian Chemical Society ; Vol. 11, issue. 2 , April , 2014 , p. 441-446
  8. URL: http://link.springer.com/article/10.1007%2Fs13738-013-0316-3