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Highly efficient synthesis of pyrimido[4,5-d]pyrimidine-2,4-dione derivatives catalyzed by iodine

Moghaddam, F. M ; Sharif University of Technology

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  1. Type of Document: Article
  2. DOI: 10.1016/j.tetlet.2014.07.006
  3. Abstract:
  4. A new and efficient synthesis of pyrimido[4,5-d]pyrimidine-2,4-dione derivatives through the reaction of 6-aminouracils and N,N′-bis(arylmethylidene) arylmethane in the presence of molecular iodine as a readily available and feasible catalyst
  5. Keywords:
  6. Cycloaddition reaction ; Enaminones ; Pyrimido[4,5-d]pyrimidine ; Iodine ; pyrimidine derivative ; pyrimido[4,5 d]pyrimidine 2,4 dione derivative ; Unclassified drug ; Article ; Carbon nuclear magnetic resonance ; Catalysis ; Cycloaddition ; Drug synthesis ; Infrared spectroscopy ; Proton nuclear magnetic resonance
  7. Source: Tetrahedron Letters ; 2014 , p. 4720-4723
  8. URL: http://www.sciencedirect.com/science/article/pii/S0040403914011472