Discovering new medicines and generally medical researches, are time consuming and expensive. But recent achievements in cell culturing methods and micro and nano-engineering techniques have enabled the researchers to investigate new medicines in a lesser time and price. Huh et al. successfully fabricated the lung on chip device. This device is consisted of three chambers. The middle chamber is separated in two equal parts and side chambers were considered in order to apply normal breathing. Periodic deformation was needed to apply the natural condition of cultured cells by expansion and contraction. Numerical simulation was needed to investigate the properties of flow in this kind of...