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Carbon-Pt nanoparticles modified TiO 2 nanotubes for simultaneous detection of dopamine and uric acid

Mahshid, S ; Sharif University of Technology

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  1. Type of Document: Article
  2. DOI: 10.1166/jnn.2011.4201
  3. Abstract:
  4. The present work describes sensing application of modified TiO 2 nanotubes having carbon-Pt nanoparticles for simultaneous detection of dopamine and uric acid. The TiO 2 nanotubes electrode was prepared using anodizing method, followed by electrodeposition of Pt nanoparticles onto the tubes. Carbon was deposited by decomposition of polyethylene glycol in a tube furnace to improve the conductivity. The C-Pt-TiO 2 nanotubes modified electrode was characterized by cyclic voltam-metry and differential pulse voltammetry methods. The modified electrode displayed high sensitivity towards the oxidation of dopamine and uric acid in a phosphate buffer solution (pH 7.00). The electro-oxidation currents of dopamine and uric acid were linearly related to the concentration over a wide range of 3.5 × 10 -8 M to 1 × 10 -5 M and 1 × 10 -7 M to 3 × 10 -5 M respectively. The limit of detection was determined as 2 × 10 -10 M for dopamine at signal-to-noise ratio of 3. The interference of uric acid was also investigated. Electro-oxidation currents of dopamine in the presence of fix amount of uric acid represented a linear behaviour towards successive addition of dopamine in range of 1 × 10 -7 M to 1 × 10 -5 M. Furthermore, in a solution containing dopamine, uric acid and ascorbic acid the overlapped oxidation peaks of dopamine and ascorbic acid could be easily separated by using C-Pt-TiO 2 nanotubes modified electrode
  5. Keywords:
  6. Biosensor ; Carbon ; Pt nanoparticles ; TiO 2 ; Anodizing methods ; Ascorbic acids ; Differential pulse voltammetry ; High sensitivity ; Limit of detection ; Modified electrodes ; Oxidation peak ; Phosphate buffer solutions ; Sensing applications ; Signal to noise ; Simultaneous detection ; TiO ; Tube furnaces ; Uric acids ; Biosensors ; Ketones ; Nanoparticles ; Nanotubes ; Organic acids ; Oxidation ; Polyethylene glycols ; Tubes (components) ; Voltammetry ; Neurophysiology ; Metal nanoparticle ; Titanium ; Titanium dioxide ; Uric acid ; Chemistry ; Oxidation reduction reaction ; Scanning electron microscopy ; Carbon ; Dopamine ; Electrochemistry ; Metal nanoparticles ; Microscopy, electron, scanning ; Oxidation-reduction ; Platinum
  7. Source: Journal of Nanoscience and Nanotechnology ; Volume 11, Issue 8 , 2011 , Pages 6668-6675 ; 15334880 (ISSN)
  8. URL: http://www.ingentaconnect.com/content/asp/jnn/2011/00000011/00000008/art00004?token=00501c3054436d93e2ae275c277b42573167527655256f4523792f592f653b672c57582a72752d70