Superparamagnetic nanoparticles for epilepsy detection

Pedram, M. Z ; Sharif University of Technology | 2015

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  1. Type of Document: Article
  2. DOI: 10.1007/978-3-319-19387-8_301
  3. Publisher: Springer Verlag , 2015
  4. Abstract:
  5. Epilepsy is the most common neurological disorder that is known with uncontrolled seizure. Around 30% of patients with epilepsy resist to all forms of medical treatments and therefore, the removal of epileptic brain tissue is the only solution to get these patients free from chronical seizures. The precise detection of an epileptic zone is key to its treatment. In this paper, we propose a method of epilepsy detection using brain magnetic field. The possibility of superparamagnetic nanoparticle (SPMN) as sensors for the detection of the epileptic area inside the brain is investigated. The aggregation of nanoparticles in the weak magnetic field of epileptic brain is modeled using potential energy minimization technique between each two SPMNs. The results show that nanoparticles tend to be aggregated as induced by weak magnetic field (pT). Nanoparticles aggregation can be used as a marker to increase the contrast of MRI images in epileptic brain area
  6. Keywords:
  7. Brain Magnetic Field ; Paramagnetic Nano-Particle ; Biomedical engineering ; Brain ; Magnetic fields ; Magnetic resonance imaging ; Magnetism ; Nanoparticles ; Neurology ; Potential energy ; Superparamagnetism ; Brain magnetic fields ; Epilepsy ; Epilepsy detection ; Medical treatment ; Neurological disorders ; Potential energy minimization ; Superparamagnetic nanoparticles ; Weak magnetic fields ; Nanomagnetics
  8. Source: World Congress on Medical Physics and Biomedical Engineering, 2015, 7 June 2015 through 12 June 2015 ; Volume 51 , June , 2015 , Pages 1237-1240 ; 16800737 (ISSN) ; 9783319193878 (ISBN)
  9. URL: http://link.springer.com/chapter/10.1007%2F978-3-319-19387-8_301