Shear-rate-dependent rheology effects on mass transport and surface reactions in biomicrofluidic devices

Sadeghi, A ; Sharif University of Technology | 2015

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  1. Type of Document: Article
  2. DOI: 10.1002/aic.14781
  3. Publisher: John Wiley and Sons Inc , 2015
  4. Abstract:
  5. Consideration is given to shear-rate-dependent rheology effects on mass transport in a heterogeneous microreactor of rectangular cross section, utilizing both numerical and analytical approaches. The carrier liquid obeys the power-law viscosity model and is actuated primarily by an electrokinetic pumping mechanism. It is discovered that, considering the shear-thinning biofluids to be Newtonian fluids gives rise to an overestimation of the saturation time. The degree of overestimation is higher in the presence of large Damkohler numbers and electric double layer thicknesses. It is also increased by the application of a favorable pressure gradient, whereas the opposite is true when an opposed pressure gradient is applied. In addition, a channel of square cross section corresponds to the maximum fluid rheology effects. Finally, the numerical results indicate the existence of a concentration wave when using long channels. This is confirmed by analytical solutions, providing a closed form solution for wave propagation speed
  6. Keywords:
  7. Mass transport ; Surface reaction ; Elasticity ; Electroosmosis ; Mass transfer ; Microfluidics ; Newtonian liquids ; Pressure gradient ; Shear deformation ; Shear flow ; Shear thinning ; Surface reactions ; Wave propagation ; Closed form solutions ; Electric double layer thickness ; Electrokinetic pumping ; Electroosmotic flow ; Favorable pressure gradients ; Non-Newtonian fluids ; Rectangular cross-sections ; Square cross section ; Transport properties
  8. Source: AIChE Journal ; Volume 61, Issue 6 , 2015 , Pages 1912-1924 ; 00011541 (ISSN)
  9. URL: http://onlinelibrary.wiley.com/doi/10.1002/aic.14781/abstract