Electrochemical study of Azathioprine at thin carbon nanoparticle composite film electrode

Shahrokhian, S ; Sharif University of Technology | 2009

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  1. Type of Document: Article
  2. DOI: 10.1016/j.elecom.2009.05.025
  3. Publisher: 2009
  4. Abstract:
  5. Thin carbon nanoparticle/Nafion film (CNP/N), as a novel electrode material, is formed on the surface of the glassy carbon electrode in a simple solvent evaporation process. The electrochemical behavior of Azathioprine (Aza) at the CNP/N-modified electrode is investigated in detail by the means of cyclic voltammetry. During the electrochemical reduction of Aza, an irreversible cathodic peak is appeared. Cyclic voltammetric studies indicated that the reduction process has an irreversible and adsorption-like behavior. The observed reduction peak is attributed to a four-electron process referring to the reduction of nitro group to the corresponding hydroxylamine. The prepared electrode showed an excellent catalytic activity toward the electro-reduction of Aza leading to a significant improvement in sensitivity as compared to the bare glassy carbon electrode where the electrochemical activity for this compound is very weak. © 2009 Elsevier B.V. All rights reserved
  6. Keywords:
  7. Azathioprine ; Carbon nanoparticle ; Modified electrode ; Nafion ; Voltammetry ; Carbon nano particles ; Catalytic activity ; Cathodic peak ; Electro reduction ; Electrochemical activities ; Electrochemical behaviors ; Electrochemical reductions ; Electrochemical studies ; Electrode material ; Four-electron process ; Glassy carbon electrodes ; Modified electrodes ; Nitro group ; Reduction peak ; Reduction process ; Solvent evaporation ; Voltammetric studies ; Adsorption ; Amines ; Composite films ; Electrodes ; Electrolytic reduction ; Glass membrane electrodes ; Nanoparticles ; Cyclic voltammetry
  8. Source: Electrochemistry Communications ; Volume 11, Issue 7 , 2009 , Pages 1425-1428 ; 13882481 (ISSN)
  9. URL: https://www.sciencedirect.com/science/article/pii/S1388248109002343