Prevalence of hepatitis e infection in the general population of Iran: a systematic review and meta-analysis

Hadifar, S ; Sharif University of Technology

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  1. Type of Document: Article
  2. DOI: 10.2217/fvl-2016-0112
  3. Abstract:
  4. Aim: Hepatitis E is a form of acute viral hepatitis, which is caused by hepatitis E virus (HEV). The study objective was to evaluate the prevalence of HEV to provide an overall relative frequency in Iran. Methods: In this study, databases such as PubMed and Scopus were searched using the following keywords according to MeSH, "Hepatitis E virus", "Epidemiology", "Enzyme-linked immunosorbent assay (ELISA)" and "Iran". Then studies which had reported prevalence of HEV were selected. Results: We selected 36 researches out of 9246 for our study. From all the samples, the pooled estimated prevalence of HEV positive was 9.7%. It should be noted that HEV infection's relative frequency varied from 1.1% in Tehran to 46.1% in Ahvaz. Conclusion: HEV is common in Iran, although comparing to some neighboring countries, its prevalence is lower. © 2017 Future Medicine Ltd
  5. Keywords:
  6. ELISA ; Epidemiology ; Hepatitis E ; Hepatitis E virus ; Human ; Immunoadsorption ; Meta analysis ; Nonhuman ; Population ; Prevalence ; Priority journal ; Review ; Rotavirus ; Sensitivity analysis ; Seroprevalence ; Systematic review
  7. Source: Future Virology ; Volume 12, Issue 4 , 2017 , Pages 227-236 ; 17460794 (ISSN)
  8. URL: https://www.futuremedicine.com/doi/10.2217/fvl-2016-0112