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- Type of Document: M.Sc. Thesis
- Language: Farsi
- Document No: 50723 (06)
- University: Sharif University of Technology
- Department: Chemical and Petroleum Engineering
- Advisor(s): Mohammadi, Ali Asghar
- Abstract:
- The main goals of this research are design, simulation, and fabrication of a microfluidic system working based on dielectrophoresis. This research divided into two different parts, the first of which is the simulation of a microfluidic system, and second of which is an attempt for fabrication of microfluidic system. For the fabrication of the microfluidic system, different methods were used. In the simulation part, the enrichment of different particles was investigated, and the effects of different parameters on the enrichment were assessed. It was observed that as flow rate increases, the enrichment amount diminishes. Furthermore, as the microfluidic depth decreases, the enrichment amount usually increases. Nonetheless, in some cases, as the depth decreases, the enrichment amount decreases as well. In these cases, the effect of drag force enhancement overcomes the effect of increasing the dielectrophoresis force. Finally, the microfluidic system was optimized with the use of Design expert software. The optimization results show that for the enrichment of polystyrene particles, the appropriate depth, voltage, and flow rate are 355 micrometers, 28 voltages, and 20 microlitres per minute respectively, and for the enrichment of yeasts, appropriate depth, voltage, and flow rate are 100 micrometers, 47.99 voltages, and 24.43 microlitres per minute respectively
- Keywords:
- Simulation ; Experiments Design ; Optimization ; Dielectrophoresis Technique ; Microfluidic System
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