Direct growth of metal-organic frameworks thin film arrays on glassy carbon electrode based on rapid conversion step mediated by copper clusters and hydroxide nanotubes for fabrication of a high performance non-enzymatic glucose sensing platform

Shahrokhian, S ; Sharif University of Technology | 2018

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  1. Type of Document: Article
  2. DOI: 10.1016/j.bios.2018.04.039
  3. Publisher: Elsevier Ltd , 2018
  4. Abstract:
  5. The direct growth of self-supported metal-organic frameworks (MOFs) thin film can be considered as an effective strategy for fabrication of the advanced modified electrodes in sensors and biosensor applications. However, most of the fabricated MOFs-based sensors suffer from some drawbacks such as time consuming for synthesis of MOF and electrode making, need of a binder or an additive layer, need of expensive equipment and use of hazardous solvents. Here, a novel free-standing MOFs-based modified electrode was fabricated by the rapid direct growth of MOFs on the surface of the glassy carbon electrode (GCE). In this method, direct growth of MOFs was occurred by the formation of vertically aligned arrays of Cu clusters and Cu(OH)2 nanotubes, which can act as both mediator and positioning fixing factor for the rapid formation of self-supported MOFs on GCE surface. The effect of both chemically and electrochemically formed Cu(OH)2 nanotubes on the morphological and electrochemical performance of the prepared MOFs were investigated. Due to the unique properties of the prepared MOFs thin film electrode such as uniform and vertically aligned structure, excellent stability, high electroactive surface area, and good availability to analyte and electrolyte diffusion, it was directly used as the electrode material for non-enzymatic electrocatalytic oxidation of glucose. Moreover, the potential utility of this sensing platform for the analytical determination of glucose concentration was evaluated by the amperometry technique. The results proved that the self-supported MOFs thin film on GCE is a promising electrode material for fabricating and designing non-enzymatic glucose sensors. © 2018 Elsevier B.V
  6. Keywords:
  7. Amperometry ; Direct growth, MOFs thin film ; Glassy carbon electrode ; Non-enzymatic glucose sensor ; Surface modification ; Copper compounds ; Crystalline materials ; Electrocatalysis ; Electrolytes ; Fabrication ; Film growth ; Film preparation ; Glucose sensors ; Nanotubes ; Organometallics ; Surface treatment ; Thin films ; Yarn ; Analytical determination ; Direct growth ; Electro-catalytic oxidation ; Electroactive surface areas ; Electrochemical performance ; Glassy carbon electrodes ; Non-enzymatic glucose sensors ; Glass membrane electrodes ; Copper hydroxide nanotube ; Electrolyte ; Hydroxide ; Metal organic framework ; Nanotube ; Unclassified drug ; Carbon nanotube ; Hydroxide ion ; Article ; Chemical modification ; Chemical structure ; Controlled study ; Diffusion ; Glassy carbon electrode ; Glucose assay ; Glucose oxidation ; Nanofabrication ; Non enzymatic glucose sensor ; Surface area ; Surface property ; Chemistry ; Electrochemical analysis ; Electrode ; Genetic procedures ; Isolation and purification ; Oxidation reduction reaction ; Biosensing Techniques ; Catalysis ; Copper ; Electrochemical Techniques ; Electrochemistry ; Electrodes ; Glass ; Glucose ; Hydroxides ; Metal-Organic Frameworks ; Nanotubes, Carbon ; Oxidation-Reduction
  8. Source: Biosensors and Bioelectronics ; Volume 112 , 2018 , Pages 100-107 ; 09565663 (ISSN)
  9. URL: https://www.sciencedirect.com/science/article/pii/S0956566318302999?via%3Dihub