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The Impedimetric Human Papiloma Virous DNA Biosensor Fabrication Based on Gold Nanotubes, Ph.D. Dissertation Sharif University of Technology ; Ghorbani, Mohammad (Supervisor) ; Sasanpour, Pezhman (Supervisor)
Abstract
An impedimetric human papilloma virus (HPV) DNA biosensor based on gold nanotubes (AuNTs) in label free detection was materialized. The AuNTs decorated nanoporous polycarbonate (AuNTs-PC) template as biosensor electrode was fabricated by electrodeposition method. The single strand DNA (ss-DNA) probe was covalently immobilized onto the AuNTs-PC electrode. The hybridization of target sequences with the ss-DNA probe was observed by the electrochemical impedance spectroscopy (EIS). The biosensor showed high selectivity and could differentiate between the complementary, mismatch and non-complementary DNA sequences. The EIS measurements were matched to Randle's equivalent circuit. The...
Cataloging briefThe Impedimetric Human Papiloma Virous DNA Biosensor Fabrication Based on Gold Nanotubes, Ph.D. Dissertation Sharif University of Technology ; Ghorbani, Mohammad (Supervisor) ; Sasanpour, Pezhman (Supervisor)
Abstract
An impedimetric human papilloma virus (HPV) DNA biosensor based on gold nanotubes (AuNTs) in label free detection was materialized. The AuNTs decorated nanoporous polycarbonate (AuNTs-PC) template as biosensor electrode was fabricated by electrodeposition method. The single strand DNA (ss-DNA) probe was covalently immobilized onto the AuNTs-PC electrode. The hybridization of target sequences with the ss-DNA probe was observed by the electrochemical impedance spectroscopy (EIS). The biosensor showed high selectivity and could differentiate between the complementary, mismatch and non-complementary DNA sequences. The EIS measurements were matched to Randle's equivalent circuit. The...
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