Revealing electrical stresses acting on the surface of protoplast cells under electric field

Dastani, K ; Sharif University of Technology | 2019

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  1. Type of Document: Article
  2. DOI: 10.1016/j.euromechflu.2019.02.010
  3. Publisher: Elsevier Ltd , 2019
  4. Abstract:
  5. When cells exposed to an electric field, localized changes in the distribution of the electric field will be induced and these changes in turn lead to electrical stresses on cell surface. The electrical stresses play a key role in the cell membrane structural changes which leads to important phenomena like hydrophilic pores formation on the cell membrane resulting in the cell permeability. In this work, protoplast cell interaction with direct current (DC) electric field is investigated. The electrical stresses acted on the cell membrane in the presence of electric field are investigated numerically by a modified finite difference method, fast Immersed Interface Method (IIM). Exact solution of dielectrophoresis (DEP) force applied on a cell under a non-uniform electric field is obtained to verify numerical solution obtained by the fast IIM. The numerical results reveal that both mismatched permittivity between cell and insulating suspension fluid and the applied voltage are essential for generating and tuning the total stresses exerted on cell surface. This paper can help to analytically study the electroporation phenomenon which its exact mechanism is still unclear. © 2019 Elsevier Masson SAS
  6. Keywords:
  7. BioMEMS ; Dielectrophoresis ; Immersed interface method (IIM) ; Microfluidics ; Cell membranes ; Cytology ; Electric fields ; Electrophoresis ; Electroporation ; Finite difference method ; Plants (botany) ; Suspensions (fluids) ; Cell permeability ; Electrical stress ; Hydrophilic pores ; Immersed interface method ; Modified finite difference methods ; Nonuniform electric field ; Numerical results ; Numerical solution ; Cell engineering
  8. Source: European Journal of Mechanics, B/Fluids ; Volume 76 , 2019 , Pages 292-302 ; 09977546 (ISSN)
  9. URL: https://www.sciencedirect.com/science/article/abs/pii/S0997754618305120