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Modeling of Genetic Mutations Associated with Protein Pathway Common in Alzheimer, Parkinson and Macular Degeneration Diseases, M.Sc. Thesis Sharif University of Technology ; Jahed, Mehran (Supervisor) ; Hossein Khalaj, Babak (Supervisor) ; Shahpasand, Kourosh (Co-Supervisor)
Abstract
Extensive studies have been performed on the genetic variations involved in common neurodegenerative diseases such as Alzheimer's, macular degeneration, and Parkinson's. In most cases, no specific gene has been identified pointing to a distinct pathogenic pathway, therefore, this study mainly aims to find common genes among aforementioned diseases according to determination of a specific pathogenic protein pathway.In this study, we reached a deep understanding of the function of nervous system and the discovery of causative agents of the diseases by applying the sources of information from genome datasets in bioinformatics analysis. The utilized database comprises the classification of...
Cataloging briefModeling of Genetic Mutations Associated with Protein Pathway Common in Alzheimer, Parkinson and Macular Degeneration Diseases, M.Sc. Thesis Sharif University of Technology ; Jahed, Mehran (Supervisor) ; Hossein Khalaj, Babak (Supervisor) ; Shahpasand, Kourosh (Co-Supervisor)
Abstract
Extensive studies have been performed on the genetic variations involved in common neurodegenerative diseases such as Alzheimer's, macular degeneration, and Parkinson's. In most cases, no specific gene has been identified pointing to a distinct pathogenic pathway, therefore, this study mainly aims to find common genes among aforementioned diseases according to determination of a specific pathogenic protein pathway.In this study, we reached a deep understanding of the function of nervous system and the discovery of causative agents of the diseases by applying the sources of information from genome datasets in bioinformatics analysis. The utilized database comprises the classification of...
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