Selective fluorometric determination of sulfadiazine based on the growth of silver nanoparticles on graphene quantum dots

Afsharipour, R ; Sharif University of Technology | 2020

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  1. Type of Document: Article
  2. DOI: 10.1007/s00604-019-4001-9
  3. Publisher: Springer , 2020
  4. Abstract:
  5. A sensitive fluorometric assay is described for the direct determination of the antibiotic sulfadiazine. Silver nanoparticles placed on graphene quantum dots (Ag NP-GQDs) were synthesized by reduction of AgNO3 with sodium borohydride in the presence of GQDs. The growth of Ag NPs on the surface of the GQDs causes quenching of the blue fluorescence of the GQDs with an emission maximum at 470 nm by surface-enhanced energy transfer. If sulfadiazine is added, it interacts with Ag NPs and fluorescence is restored. Under optimal conditions, the fluorescence increases linearly in the sulfadiazine concentration range of 0.04–22.0 μM. The detection limit is 10 nM with relative standard deviations of 2.3 and 4.2 (at 10 μM of sulfadiazine; for n = 6) for intra- and inter-day assays. [Figure not available: see fulltext.]. © 2019, Springer-Verlag GmbH Austria, part of Springer Nature
  6. Keywords:
  7. AgNPs-GQDs ; Antibiotic ; Fluorescence intensity ; Nanoprobe ; Serum analysis ; Surface-enhanced energy transfer ; Urine analysis ; Antiinfective agent ; Metal nanoparticle ; Quantum dot ; Chemistry ; Surface property ; Anti-Bacterial Agents ; Fluorometry ; Graphite ; Metal Nanoparticles ; Particle Size ; Quantum Dots ; Silver ; Sulfadiazine ; Surface Properties
  8. Source: Microchimica Acta ; Volume 187, Issue 1 , 2020
  9. URL: https://link.springer.com/article/10.1007/s00604-019-4001-9