Deep eutectic solvents: Cutting-edge applications in cross-coupling reactions

Hooshmand, S. E ; Sharif University of Technology | 2020

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  1. Type of Document: Article
  2. DOI: 10.1039/d0gc01494j
  3. Publisher: Royal Society of Chemistry , 2020
  4. Abstract:
  5. Deep eutectic solvents (DESs), surmised as "the organic reaction medium of the century", have reverberated a new symphony throughout the present green millennium. A brief historical account of the DES systems and their physicochemical properties as task-specific and designer solvents for cross-coupling reactions are appraised including the hole theory that explains the underlying mechanistic pathway for this emerging neoteric medium. The insights into cross-coupling reactions and their applications are included, highlighting the significant achievements pertaining to the dual role of DESs as a solvent and catalyst. In addition, popular "name-reactions"for the carbon-carbon and carbon-heteroatom bond formations related to the nature of DESs and the core optimum conditions are included. The review also encompasses the novel approaches to privileged catalytic systems and identify the voids left in cross-coupling reactions where DES systems have not made inroads yet. Finally, the challenges of utilizing the neoteric derivatives of DES for these reactions are expounded. © 2020 The Royal Society of Chemistry
  6. Keywords:
  7. Carbon ; Eutectics ; Physicochemical properties ; Solvents ; Carbon-heteroatom bonds ; Catalytic system ; Cross coupling reactions ; Deep eutectic solvents ; Historical account ; Mechanistic pathways ; Optimum conditions ; Organic reaction ; Chemical reactions
  8. Source: Green Chemistry ; Volume 22, Issue 12 , 2020 , Pages 3668-3692
  9. URL: https://pubs.rsc.org/en/content/articlelanding/2020/gc/d0gc01494j#!divAbstract