Atherosclerosis, due to the penetration of low-density lipoprotein particles (LDL) into the arterial wall, is one of the most common and death-leading diseases in today's world. Due to its importance, extensive research has been conducted on the factors that affect this disease. In this thesis, a numerical study of the effects of Wall Shear Stress (WSS), non-Newtonian behavior of blood, different hematocrit values, and blood pressure on LDL permeation through the artery wall layers are investigated in a 4-layer wall model of a coronary bifurcation. To obtain the velocity and concentration fields in the domain, momentum, Brinkman, and mass transport equations are solved in the lumen and wall...