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Lithium perchlorate mediated three-component preparation of α-aminonitriles under solvent-free conditions

Azizi, N ; Sharif University of Technology | 2004

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  1. Type of Document: Article
  2. DOI: 10.1081/SCC-120030307
  3. Publisher: 2004
  4. Abstract:
  5. A three-component reaction between aliphatic or aromatic aldehyde, an amine and trimethylsilyl cyanide mediated by solid LiClO4, gave amino nitriles in good to excellent yields. The reaction proceeded smoothly under solvent-free conditions without any side products
  6. Keywords:
  7. α-Aminonitriles ; Lithium perchlorate ; Solvent-free conditions ; Three-component condensation
  8. Source: Synthetic Communications ; Volume 34, Issue 7 , 2004 , Pages 1207-1214 ; 00397911 (ISSN)
  9. URL: https://www.tandfonline.com/doi/abs/10.1081/SCC-120030307