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Chlorophyll-based wicking sensing bioplatform coupled with a smartphone-based sample-to-answer analytical device for on-site detection of picric acid
, Article Biosensors and Bioelectronics: X ; Volume 11 , 2022 ; 25901370 (ISSN) ; Abbasi Moayed, S ; Hamzei, Z ; Keshavarz, A ; Yousefi, S ; Hormozi Nezhad, M. R ; Golmohammadi, H ; Sharif University of Technology
Elsevier Ltd
2022
Abstract
The development of inexpensive, equipment-free, portable, and user/environmentally-friendly analytical devices that can be efficiently utilized for on-site detection of PA is still a great challenge. To address these unmet demands, we have developed a smartphone-based disposable sensing bioplatform through immobilization of chlorophyll in a cotton thread for fluorescent monitoring of picric acid (PA). The fluorescence quenching of chlorophyll upon increasing the PA concentration based on the inner filter effect was considered as the sensing strategy in the developed sensor. The fabricated thread-based microfluidic sensing bioplatform was further coupled with a compact, low cost, portable,...
Assessment of fiber-reinforcement and foam-filling in the directional energy absorption performance of a 3D printed accordion cellular structure
, Article Composite Structures ; Volume 297 , 2022 ; 02638223 (ISSN) ; Mahdi Ashrafian, M ; Behravesh, A. H ; Kaveh Hedayati, S ; Sharif University of Technology
Elsevier Ltd
2022
Abstract
This paper presents an evaluation of two distinct techniques to improve energy absorption capability of an accordion cellular structure with close-to-zero Poisson's ratio. For this purpose, fiber-reinforcement and foam-filling methods were employed to address the material enhancement and to obtain light and tough structures with high specific energy absorption. Employing an innovated additive manufacturing based on material extrusion process, specimens of glass fiber-reinforced PLA were produced in both in-plane directions to compare with the un-reinforced counterpart. In continue, some of the 3D printed samples were strengthened by means of polyurethane foam in their hollow structure. The...
Microfluidic-assisted fiber production: Potentials, limitations, and prospects
, Article Biomicrofluidics ; Volume 16, Issue 6 , 2022 ; 19321058 (ISSN) ; Nilghaz, A ; Saadatmand, M ; Naeimirad, M ; Demello, A. J ; Sharif University of Technology
American Institute of Physics Inc
2022
Abstract
Besides the conventional fiber production methods, microfluidics has emerged as a promising approach for the engineered spinning of fibrous materials and offers excellent potential for fiber manufacturing in a controlled and straightforward manner. This method facilitates low-speed prototype synthesis of fibers for diverse applications while providing superior control over reaction conditions, efficient use of precursor solutions, reagent mixing, and process parameters. This article reviews recent advances in microfluidic technology for the fabrication of fibrous materials with different morphologies and a variety of properties aimed at various applications. First, the basic principles, as...
Developing an Off-the-Shelf microfluidic droplet generation device for cell encapsulation
, Article Industrial and Engineering Chemistry Research ; Volume 61, Issue 30 , 2022 , Pages 10689-10699 ; 08885885 (ISSN) ; Shamloo, A ; Sharif University of Technology
American Chemical Society
2022
Abstract
Droplet microfluidics is a platform of microfluidics in which two immiscible fluids are used to generate droplets for various biomedical applications. This platform introduces several advantages in applications such as cell lysis, cell culture, co-culture, and cell encapsulation. The most important issues regarding droplet generation devices are the fabrication complexity and maintenance of these devices. In this study, a simple and easy-to-fabricate microdroplet generator is designed and fabricated to resolve these issues. Furthermore, since this device is easy to fabricate and use, it can play a key role in the fabrication of medical devices for controlling infectious diseases in poor and...
Design and characterization of an orthotropic accordion cellular honeycomb as one-dimensional morphing structures with enhanced properties
, Article Journal of Sandwich Structures and Materials ; Volume 24, Issue 3 , 2022 , Pages 1726-1745 ; 10996362 (ISSN) ; Ashrafian, M. M ; Fotouhi, M ; Sharif University of Technology
SAGE Publications Ltd
2022
Abstract
This study develops the governing equations and characterizes the mechanical properties of a new orthotropic accordion morphing honeycomb structure containing periodic arrays of U-type beams reinforced with glass fibers. Castigliano’s second theorem is modified to develop the analytical equations to predict the deformation behavior of a single orthotropic ply under a combined axial, bending, and shear loadings. Accordingly, the elastic properties of the orthotropic structure including elastic stiffness, shear stiffness, and in-plane Poisson’s ratios are calculated by the developed equations. The honeycomb structure is manufactured by 3D printing, and the samples are subjected to tensile...
Effects of plate contouring quality on the biomechanical performance of high tibial osteotomy fixation: A parametric finite element study
, Article Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine ; Volume 236, Issue 3 , 2022 , Pages 356-366 ; 09544119 (ISSN) ; Farahmand, F ; Sharif University of Technology
SAGE Publications Ltd
2022
Abstract
Locking plates have threaded holes, in which threaded-head screws are affixed. Hence, they do not need to be in intimate contact with underlying bone to provide fixation. There are, however, reports that a large distance between the plate and the bone might cause clinical complications such as delayed union or nonunion, screw pull out, and screw and plate breakage. Considering the diversity in the capabilities and costs of different plate customization techniques, the purpose of this study was to investigate the effect of the plate contouring quality on the biomechanical performance of high tibial osteotomy (HTO) fixation. A finite element model of proximal tibia was developed in Abaqus,...
Effect of laser additive manufacturing parameters on hardness and geometry of Inconel 625 parts manufactured by direct laser metal deposition
, Article Optik ; Volume 249 , 2022 ; 00304026 (ISSN) ; Akbari, J ; Moradi, M ; Malekshahi Beiranvand, Z ; Sharif University of Technology
Elsevier GmbH
2022
Abstract
This research investigates the effect of process parameters on the geometry and properties of In625 parts, manufactured by the direct laser metal deposition (DLMD) process. For this purpose, eight parts, consisting of 5 layers on top of each other, were manufactured, and the effect of laser power, laser focal plane position, and scanning speed on the height, width, and surface smoothness of each of them was investigated using design of experiment (DOE). The experimental results showed that the height of the parts manufactured by 800 W/mm and 200 W/mm of energy density is 3.69 mm and 6.12 mm, respectively. The thickness of the parts manufactured by 80 W/mm and 200 W/mm of energy density is...
Effect of building direction on high strain-rate compressive behavior of heat-treated LPBF-maraging steels using Split Hopkinson pressure bar apparatus
, Article Materials Science and Engineering A ; Volume 835 , 2022 ; 09215093 (ISSN) ; Pirgazi, H ; Sanjari, M ; Seraj, P ; Odeshi, A ; Kestens, L. A. I ; Mohammadi, M ; Sharif University of Technology
Elsevier Ltd
2022
Abstract
Rod-shaped samples of maraging steel were additively fabricated in vertical and horizontal directions using laser powder bed fusion technique. The samples were first aged at 490 °C for 6 h and then subjected to dynamic compressive tests using Split Hopkinson Pressure Bar apparatus. The dynamic compression tests were conducted on vertical samples at strain rates of 190, 460, 810, 1100, 1300 s−1. However, the high strain rate tests were performed at strain rates of 120, 615, 745, 890, 2200 s−1 on horizontal samples. After applying the compressive impact loads on the samples, it was found that although horizontally built samples exhibit higher dynamic strength, vertically built samples show...
Colloidal particle reaction and aggregation control in the Electrohydrodynamic 3D printing technology
, Article International Journal of Mechanical Sciences ; Volume 195 , 2021 ; 00207403 (ISSN) ; Movahhedy, M. R ; Khodaygan, S ; Sharif University of Technology
Elsevier Ltd
2021
Abstract
The electrohydrodynamic (EHD) 3D printing technology is an Additive Manufacturing (AM) method that can be used in the manufacture of submicron-size structures. In this process, which is based on the formation of Taylor jet from a metallic ink, the investigation of particles reaction and aggregate formation in ink during printing is of great importance. In this paper, a new Finite Element model based on particle tracing in fluids is presented that couples the different physics that govern an EHD phenomenon. Vortex flow caused by boundary shear stress was observed in the ink jet; which was more like the Marangoni phenomenon in a stationary drop. By experimentally validating the presented model...
An autonomous framework for interpretation of 3D objects geometric data using 2D images for application in additive manufacturing
, Article PeerJ Computer Science ; Volume 7 , 2021 , Pages 1-32 ; 23765992 (ISSN) ; Houshmand, M ; Valilai, O. F ; Sharif University of Technology
PeerJ Inc
2021
Abstract
Additive manufacturing, artificial intelligence and cloud manufacturing are three pillars of the emerging digitized industrial revolution, considered in industry 4.0. The literature shows that in industry 4.0, intelligent cloud based additive manufacturing plays a crucial role. Considering this, few studies have accomplished an integration of the intelligent additive manufacturing and the service oriented manufacturing paradigms. This is due to the lack of prerequisite frameworks to enable this integration. These frameworks should create an autonomous platform for cloud based service composition for additive manufacturing based on customer demands. One of the most important requirements of...
Production and characterization of Ti6Al4V/CaP nanocomposite powder for powder-based additive manufacturing systems
, Article Powder Technology ; Volume 386 , 2021 , Pages 319-334 ; 00325910 (ISSN) ; Ekrami, A ; Badrossamay, M ; Sharif University of Technology
Elsevier B.V
2021
Abstract
Ti64/CaP nanocomposite powder was fabricated and characterized for use in powder-bed 3D printing. The microstructure and phase composition, morphology, particle size distribution, sphericity, flow behavior and dispersion of the as-fabricated particles on the building plate of the 3D printer were investigated. The results confirmed a uniform distribution of nanostructured calcium phosphate particles on the surface of primary Ti64 ones. Calcium phosphate appears as an octa-calcium phosphate phase. The morphology of the particles was shown as spherical, and their sphericity was better than the as-received Ti64 particles. The particle size distribution of nanocomposite powder indicated a smaller...
Microengineered poly(HEMA) hydrogels for wearable contact lens biosensing
, Article Lab on a Chip ; Volume 20, Issue 22 , 2020 , Pages 4205-4214 ; Zhang, S ; Cui, Q ; Ni, J ; Wang, X ; Cheng, X ; Alem, H ; Tebon, P ; Xu, C ; Guo, C ; Nasiri, R ; Moreddu, R ; Yetisen, A. K ; Ahadian, S ; Ashammakhi, N ; Emaminejad, S ; Jucaud, V ; Dokmeci, M.R ; Khademhosseini, A ; Sharif University of Technology
Royal Society of Chemistry
2020
Abstract
Microchannels in hydrogels play an essential role in enabling a smart contact lens. However, microchannels have rarely been created in commercial hydrogel contact lenses due to their sensitivity to conventional microfabrication techniques. Here, we report the fabrication of microchannels in poly(2-hydroxyethyl methacrylate) (poly(HEMA)) hydrogels that are used in commercial contact lenses with a three-dimensional (3D) printed mold. We investigated the corresponding capillary flow behaviors in these microchannels. We observed different capillary flow regimes in these microchannels, depending on their hydration level. In particular, we found that a peristaltic pressure could reinstate flow in...
Evaluation of a polymer-steel laminated sheet composite structure produced by friction stir additive manufacturing (FSAM) technology
, Article Polymer Testing ; Volume 90 , 2020 ; Khodabakhshi, F ; Simchi, A ; Sharif University of Technology
Elsevier Ltd
2020
Abstract
Laminated polymer-steel composites are promising layered materials for practical applications in the automotive industry considering their superior crush resistance capacity in terms of enhanced damping potential. In this research, the sheet lamination (SL) route of friction stir additive manufacturing (FTAM) technology was implemented for the production of a poly-methyl-methacrylate (PMMA) polymer matrix composite structure as reinforced by textile stainless steel layers, and feeding of PMMA granulates inside the stirred region. Layers bonding and the soundness of composite formation during fabrication of the laminated structure were studied. Possible chemical interactions between the steel...
3D Bioprinting of oxygenated cell-laden gelatin methacryloyl constructs
, Article Advanced Healthcare Materials ; Volume 9, Issue 15 , 2020 ; Darabi, M. A ; Nasiri, R ; Sangabathuni, S ; Ertas, Y. N ; Alem, H ; Hosseini, V ; Shamloo, A ; Nasr, A. S ; Ahadian, S ; Dokmeci, M. R ; Khademhosseini, A ; Ashammakhi, N ; Sharif University of Technology
Wiley-VCH Verlag
2020
Abstract
Cell survival during the early stages of transplantation and before new blood vessels formation is a major challenge in translational applications of 3D bioprinted tissues. Supplementing oxygen (O2) to transplanted cells via an O2 generating source such as calcium peroxide (CPO) is an attractive approach to ensure cell viability. Calcium peroxide also produces calcium hydroxide that reduces the viscosity of bioinks, which is a limiting factor for bioprinting. Therefore, adapting this solution into 3D bioprinting is of significant importance. In this study, a gelatin methacryloyl (GelMA) bioink that is optimized in terms of pH and viscosity is developed. The improved rheological properties...
Ferrofluid droplet formation from a nozzle using alternating magnetic field with different magnetic coil positions
, Article Journal of Magnetism and Magnetic Materials ; Volume 498 , 2020 ; Bijarchi, M. A ; Shafii, M. B ; Sharif University of Technology
Elsevier B.V
2020
Abstract
Ferrofluid has been used in many fields, such as microfluidics, droplet formation, and heat transfer, due to its potential to be attracted in the presence of a magnetic field. Droplet formation, itself, has many applications such as emulsions, 3D micro-printers, MEMS, and electro-sprays. In this study, the mechanism of ferrofluid droplet formation from the nozzle in the presence of an alternating magnetic field was investigated. The magnetic coil was fixed at different angles with respect to gravity and the effect of the alternating magnetic field and the angle of the magnetic coil axis with respect to gravity on the produced droplet volume, satellite droplet, and droplet formation frequency...
Hybrid anisotropic pentamode mechanical metamaterial produced by additive manufacturing technique
, Article Applied Physics Letters ; Volume 117, Issue 6 , 2020 ; Movahhedy, M. R ; Shishkovsky, I ; Hedayati, R ; Sharif University of Technology
American Institute of Physics Inc
2020
Abstract
Pentamode metamaterials are a type of extremal designer metamaterials, which are able to demonstrate extremely high rigidity in one direction and extremely high compliance in other directions. Pentamodes can, therefore, be considered as building blocks of exotic materials with any arbitrarily selected thermodynamically admissible elasticity tensor. The pentamode lattices can then be envisioned to be combined to construct intermediate extremal materials, such as quadramodes, trimodes, and bimodes. In this study, we constructed several primary types of anisotropic pentamode lattices (with midpoint positioning of 10%, 15%, 20%, 25%, 30%, 35%, and 42% of the main unit cell diagonal) and then...
A 3D-printed hybrid nasal cartilage with functional electronic olfaction
, Article Advanced Science ; Volume 7, Issue 5 , 2020 ; Kiaee, K ; Vela Jarquin, D ; De la Garza Hernández, R. L ; Wang, T ; Joshi, S ; Rezaei, Z ; de Melo, B. A. G ; Ge, D ; Mannoor, M. S ; Shin, S. R ; Sharif University of Technology
John Wiley and Sons Inc
2020
Abstract
Advances in biomanufacturing techniques have opened the doors to recapitulate human sensory organs such as the nose and ear in vitro with adequate levels of functionality. Such advancements have enabled simultaneous targeting of two challenges in engineered sensory organs, especially the nose: i) mechanically robust reconstruction of the nasal cartilage with high precision and ii) replication of the nose functionality: odor perception. Hybrid nasal organs can be equipped with remarkable capabilities such as augmented olfactory perception. Herein, a proof-of-concept for an odor-perceptive nose-like hybrid, which is composed of a mechanically robust cartilage-like construct and a biocompatible...
Flexible flow line scheduling considering machine eligibility in a digital dental laboratory
, Article International Journal of Production Research ; Volume 58, Issue 21 , 2020 , Pages 6513-6531 ; Fatahi Valilai, O ; Houshmand, M ; Sharif University of Technology
Taylor and Francis Ltd
2020
Abstract
Introduction of digital solutions has made dentistry more efficient and effective in response to patients’ demands. Moreover, digital solution helps participants to manage daily workflow simpler than traditional practices. Scanners, CAD/CAM software, CNC machines and 3D printers are components of digital solutions in current dentistry. Responding to patients as quickly as possible is essential in medical fields and dentistry has similar situations. On the other hand, demands in dentistry are highly customized that it makes managing orders more difficult because each order needs special design and production. Thus, this paper assesses orders in digital dentistry and develops a mathematical...
Numerical and analytical simulation of multilayer cellular scaffolds
, Article Journal of the Brazilian Society of Mechanical Sciences and Engineering ; Volume 42, Issue 5 , 2 May , 2020 ; Rahmati, S ; Nikkhoo, M ; Haghpanahi, M ; Akbari, J ; Sharif University of Technology
Springer
2020
Abstract
Due to the advent and maturity of the additive manufacturing technology, it is possible now to construct complex microstructures with unprecedented accuracy. In addition, to the influence of network unit cell types and porosities in recent years, researchers have studied the number of scaffold layers fabricated by additive manufacturing on mechanical properties. The objective of this paper is to assess the numerical and analytical simulations of the multilayer scaffolds. For this purpose, 54 different regular scaffolds with a unit cell composed of multilayer scaffolds were simulated under compressive loading and compared with the analytical relationships based on the Euler–Bernoulli and...
Pore structure evolution during sintering of HDPE particles
, Article Polymer ; Volume 183 , 2019 ; 00323861 (ISSN) ; Pircheraghi, G ; Foudazi, R ; Sharif University of Technology
Elsevier Ltd
2019
Abstract
Sintering is a processing technique in which loose particles consolidate at elevated temperatures to form porous monoliths. Sintering is also a critical stage in recent additive manufacturing method like selective laser sintering. In this study, using an affordable alternative to X-ray tomography technique, we analyze the pore structure evolution in sintered parts made of nascent high-density polyethylene (HDPE) particles in terms of pore surface genus and pore surface curvature. Also, we investigate the underlying microstructural development and macroscopic properties of sintered parts. It is observed that pore structure and macroscopic permeability are strongly influenced by the...