Sharif Digital Repository

Recent success of Deep Learning models, resulted in their evergrowing application in many fields. However these models usually require huge datasets, which can sometimes be hard to collect. One of the challenges related to medical data, is the Batch Effect; Medical data is usually gathered through multiple experiments. Each experiment might have a slightly different conditions than the other, resulting a shift in the data related to that batch. Batch effects can have more severe impact during testing time, as the shift in the data distribution could be bigger. Many methods have been proposed to reduce or remove the effect of external conditions on data distribution.Deep Learning models have... 

Paper and cardboard waste pulping consume large volumes of water, so the discharge of this effluent without proper treatment can have far-reaching environmental consequences. The color and variable COD concentration of wastewater in this industry make treating this wastewater complicated. Therefore, this study aims to reduce the COD of the wastewater treatment plant of a pulp and paper mill under different laboratory conditions to achieve environmental standards in Iran.In this study, coagulation-flocculation and the Fenton process on the wastewater entering the treatment plant were investigated first. It was found that coagulation and flocculation by 750-1250 ppm of alum coagulant and ten... 

The existing thesis investigates the removal efficiency of ammonia from wastewater using natural zeolite, and the effects of various parameters on the removal efficiency. The importance of this research is due of the fact that ammonia is among the primary contaminants of wastewater. The common method of removing ammonia is biological processes that have a number of drawbacks. The ion exchange method could be a suitable alternative to the former method. Ammonia removal from wastewater was investigated through both batch and continuous experiments. In these experiments the initial ammonia concentration in the wastewater was chosen to be 1000 mg/L, 100 mg/L. The optimum ammonia removal was... 

Due to the undeniable importance and applicability of both "batch processing" and "parallel machines" in service and industry, this survey strives to solve a real-world problem in which some identical parallel machine, capable of processing jobs in batches, are available. In batch processing the process of jobs starts and ends simultaneously. In real world the processing time of the batch is a function of some characteristics of the jobs in the batch. in this survey, for simplicity (as calculating the mentioned function is so difficult), we assume that the processing time of a batch equals the sum of the processing time of the jobs in the batch. we also have assumed that the capacity of a... 

Increasing in insider threats of the organization, made it necessary to use a security solution to investigate anomalies within the organization. Diagnosis of insider anomalies is based on examining the behavior of any entity, whether employees or systems of the organization. Entities are classified into different categories based on reported events. The high consumption of resources, the creation or elimination of entities, and the variability of their behavior over time are among the major challenges in diagnosing insider anomalies. In this research, while defining the process of diagnosing insider anomalies, a possible solution is presented considering the above challenges. In the... 

Obtaining polymers with desired properties is very important from industrial point of view. Weight average molecular weight and polydispersity are two important polymer properties. It is also important to obtain a high monomer conversion. In this thesis production of polyvinyl acetate is considered. Under special conditions, the vinyl acetate reactor dynamics become oscillatory which makes the reactor control difficult. For obtaining polymer with desired properties, an objective function which includes weight average molecular weight, polydispersity and monomer conversion has been defined. Then by minimizing this objective function the optimal temperature trajectory is obtained. In this... 

Hydroxyurea is an anticancer drug that is commonly used to treat chronic myeloid leukemia (white blood cell cancer in bone marrow), polycythemia vera (red blood cell cancer), sickle cell anemia, solid tumors, and in particular leukemia. In this research, in addition to analyzing all available methods for synthesis of hydroxyurea, the most economical method for synthesis of hydroxyurea which is Hantzsch method was chosen; then we synthesized hydroxyurea crystals using a precipitation or crystallization process. To do so, two hydroxylamine hydrochloride and potassium cyanate reactants have been used in the semi batch reactor. Since the reaction efficiency and purity of the synthesized... 

consumption of which (especially azo dyes) have been increasing nowadays, causing the increase of textile wastewaters. Usually, these wastewaters contain an immense number of dyes, and if these dyes release in the environment especially in waters, they cause some problems, such as the change of watercolor as well as taste, and affect creatures' lives severely. Moreover, If the dyes are left untreated in aquatic ecosystems, they can remain in the environment for a very long time, resulting in harmful and irreversible effects. Azo dyes are classified as mono, di-, three, azo dyes due to their bonds. Because dyes are increasingly used, nowadays, different methods are developed for the treatment... 

Cyclic distillation can bring new life in old distillation columns, by using a periodic operation mode that leads to significant benefits, such as increased column throughput, lower energy requirements and much higher separation performance. The design method for this type of column are reviewed. Among two design approaches, the Lagrangian one is selected, where equations are formulated as delay differential equations, moving from bottom to top of the column to determine feed tray location and total tray numbers. No rigorous design method is selected in order to calculate the column parameters.In this thesis, by defining an economic index that encompasses capital investment, operating costs... 

In recent years, utilization of hybrid attached and suspended growth system for modification of conventional activated sludge systems has attracted a lot of attentions. Nowadays, with development of urban areas and also introducing new emerging contaminants and as a result an increase in the influent loading of wastewater treatment facilities, the importance of upgrading and retrofitting available facilities have been highlighted. Conversion of Sequencing Batch Reactors to Sequencing Batch Biofilm Reactors is a viable solution for overcoming these problems. Eventhough several researches have been conducted on removal of different contaminants through these systems, the information about the... 

Fed-batch fermentation is a valuable and cost-effective method for bio-based production of various products such as ethanol, which has various applications in various industries.In recent years, bioethanol production has been given special attention in many countries. For this reason, the mathematical modeling of production of these products is very important for their optimal and cost-effective production. Given the transient and dynamic nature of fermentation and its specific complexity, mathematical modeling of fed-batch bioreactors is difficult and complicated. In this research, an unstructured model was used to predict the production of ethanol from blackstrap sugar cane molasses based... 

Providing security for digital information in a communication channel is a challenge in the recent years. This is due to the strength of high-speed processing resources that can threaten the security and correctness of communicating information. Using steganography method, the secret information can be hidden in an innocent media that does not attract the attention of third parties. This research discusses about steganography in images. The main goal of this research is presenting a universal steganography scheme with high steganography capacity. Using this scheme the steganographer can embed every large secret data in images securely. The reasons for selecting the subject of “Improving... 

Recently, The Earth has become warm rapidly over the past few years. This global warming is not only caused by natural phenomena, and further increased by humans and the amount of greenhouse gases in the atmosphere. Around 40 to 50 percent of energy consumption is related to information technology and communications. However, the rapid growth of electricity consumption in data centers, in addition to increased costs, data center challenges faced serious environmental pollution and more greenhouse gases. Use of renewable energy and reducing electricity costs in data centers are the important subjects for researchers around the world. Many researchers provide solutions to reduce environmental... 

The classical economic batch quantity (EBQ) model assumes that all produced items have a perfect quality. But in real-life production systems, generation of defective items is inevitable. A portion of these defective items is considered to be scrap , while the other is assumed to be reworkable and reworking them can reduce costs and increase productivity. In this thesis we have studied the economic batch quantity for a single stage production system with rework and scrapping . We want to satisfy the customer demand and minimize total costs of the system like set up costs , production costs , rework costs , holding costs , shortage costs and scrapping costs . In the first chapter of this... 

In this study, a semi-structured model for the growth and production of lactase in an aerated bioreactor by Kluyveromyces marxianus, growing on cheese whey, was developed. Three modes of culture, consisting of batch, fed-batch and a controlled-release system were investigated. Modeling was based on three metabolic pathways, representing the growth of Kluyveromyces marxianus. Lactose and oxygen consumption, cell growth, and also lactase and ethanol production rates were determined in the model. Induction was considered as the governing mechanism for enzyme production. The model showed good agreement with the experimental data in batch and fed-batch cultures. Controlled-release system is a... 

Almost all of the animal slaughter is done in slaughterhouses. Environment concerns about slaughterhouse industries have been increased as increase in their production. In this study, a DAF+SBR system was used for treatment of industrial slaughterhouse wastewater and efficiency of this system was evaluated.In DAF, we used anionic polymer and PAC as coagulant. We reached best composition in 2 ppm of AP and 200 ppm of PAC. After that DAF system run in different pressures to estimate the best operational pressure & A/S. Best operational pressure and A/S is 4 bar and 0.038. After pretreatment, biological treatment by using SBR reactor was carried out. The results of the SBR reactor showed that... 

In recent years, the demands come to data centers have increased significantly, so huge amount of energy consumption, cost of this usage and environmental effects of data centers have become serious issues. Accordingly using solar energy to provide some portion of a data center’s energy usage can reduce environmental effects efficiently. Also smarter use of this energy could decrease overall cost of energy in data center. The demands that come to a data center are categorized to critical and non-critical workloads. Running of Non-critical workload (batch job) can be moved to another time according to its deadline. This work suggests a solution that schedules batch jobs considering solar... 

This research attempts to develop the optimal solution for an inventory problem consisting of a single machine which produces items some of which may be defective. We assume that no shortages are allowed and all defective items are to be reworked. Setup cost for rework and waiting time of defectives are considered. This research consists of two different parts. In the first part we consider two different policies where in the first policy in each cycle after the regular production the machine is setup for the rework of defectives of the same cycle. In the second policy several cycles constitute a period. All the defectives produced in the period are reworked in the last cycle of that period.... 

Despite many advantages of granular sludge in anaerobic reactors (e.g. UASB), over the past few years research attention had turned towards developing aerobic granular sludge. Although much research is carried out on the formation of aerobic granules, less work is reported on how to enhance granules characteristics such as increasing in granule size, concentration, durability and stability. The aims of this study are to investigate the effects of cationic polymer on granule formation and the way to improve granule characteristics. For this purpose two SBR reactors (0.15 m diameter and 1.8 m height, R1 and R2) were used by feeding synthetic wastewater (diluted molasses, COD ranging from 1400... 

Single-cell RNA-sequencing has opened opportunities to unlock the cell transcriptome at cellular-level resolution and investigate cell population structures and cell-type-specific gene expression patterns. Previously, we were only able to perform bulk RNA sequencing regardless of the cell type composition of cell populations. Now, with the advancements in sequencing technologies, it is possible to extract cell-level and cell-type-specific sequences, related to each type of cell separately and in a scalable and high-throughput manner. For such large studies, logistical constraints inevitably dictate that data be generated separately i.e., at different times and with different operators....