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biomedical-engineering
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Total 159 records
Zygomatic bone registration based on a modified student's mixture model method
, Article 26th National and 4th International Iranian Conference on Biomedical Engineering, ICBME 2019, 27 November 2019 through 28 November 2019 ; 2019 , Pages 88-92 ; 9781728156637 (ISBN) ; Mobaraki, M ; Ahmadian, A ; Bayat, M ; Bahrami, N ; Sharif University of Technology
Institute of Electrical and Electronics Engineers Inc
2019
Abstract
Point Set Registration (PSR) of anatomic parts is used in different fields such as Patient Specific Implant (PSI) design in Computer Assisted Surgery (CAS) procedure. We designed a modified rigid PSR method based on student's-t mixture model. The proposed method is compared with Coherent Point Drift (CPD) registration method. Higher convergence speed and the lower error value are the advantages of the suggested algorithm in compare with CPD. In our method, the number of iterations decreases by about 69%, and the final error improvement was about 7% in comparison with CPD. The robustness of the proposed algorithm makes it beneficial to be used in the procedure of designing PSI in both...
Validation of the Saadat NIBP module according to the ANSI/AAMI-SP10 protocol
, Article 2013 20th Iranian Conference on Biomedical Engineering, ICBME 2013 ; Deembec , 2013 , Pages 199-202 ; Mashayekhi, G ; Behzadfar, N ; Yaghoobzadeh, A ; Babaee, T ; Sharif University of Technology
IEEE Computer Society
2013
Abstract
This study is conducted with the aim of validating the Saadat non-invasive blood pressure (NIBP) module accuracy and reliability against direct intra arterial pressure measurement (IBP) according to the ANSI/AAMI SP10-2002 guidelines. Measurement and comparison procedure were done in a static population of 19 adult patients with brachial catheterized arterial line with total measurements of 195 under supervision of a highly experienced cardiovascular anesthesiologist in accordance with the ANSI/AAMI SP10-2002 regulation. Data analysis was performed based on the protocol criteria. In order to represent relationships between the test device and the reference method, Bland-Altman graphical...
Urine concentrating mechanism modelling in rat kidney inner medulla
, Article 2016 23rd Iranian Conference on Biomedical Engineering and 2016 1st International Iranian Conference on Biomedical Engineering, ICBME 2016, 23 November 2016 through 25 November 2016 ; 2017 , Pages 111-116 ; 9781509034529 (ISBN) ; Saidi, M. S ; Banazadeh, M. H ; Sharif University of Technology
Abstract
Physicians use charts that are prepared by experiments on animals or humans to prescribe drug dosage for patients. This method requires some precious amount of time by the Ministry of Health to approve new drugs to be used in healthcare centers. Three-dimensional modeling of the inner medulla by considering the known physiological features help us to predict the distribution of a drug or any minerals in the kidney. In this study we present modeling of the important species distribution including Na+ and urea in the rat inner medulla that influence the urine concentrating mechanism. We use a C++ code to develop the inner medulla geometry based on physiological data to better capture the...
Ultrasound dosimetery using microbubbles
, Article IFMBE Proceedings, 20 June 2011 through 23 June 2011 ; Volume 35 IFMBE , June , 2011 , Pages 359-362 ; 16800737 (ISSN) ; 9783642217289 (ISBN) ; Zahedi, E ; Tavakkoli, J ; Sharif University of Technology
2011
Abstract
In this paper, a new technique based on nonlinear resonance of microbubbles is investigated in order to estimate the amplitude of an ultrasound wave pressure field. First, the existing theoretical model is reviewed. Then, an experimental setup consisting of a bubble generator and transmitting/receiving ultrasound transducers operating in the 1 MHz frequency range is described. The effect of background noise is also taken into account. Results show that the second harmonic oscillations are detectable, paving the way to develop a quantitative method for in vivo calibration of ultrasound waves
Two channel abdominal PPG instrumentation
, Article IFMBE Proceedings ; Volume 21 IFMBE, Issue 1 , 2008 , Pages 691-693 ; 16800737 (ISSN); 9783540691389 (ISBN) ; Mohd Ali, M. A ; Zahedi, E ; Sharif University of Technology
Springer Verlag
2008
Abstract
In this paper, a two channel abdominal PPG instrumentation is developed. The proposed instrument consists of IR-LED and its driver, photo-detector and data acquisition card. The modulation frequency generation, demodulation and digital signal processing is done completely in the digital domain using LabView. The results show that the developed instrument is able to acquire signal from the abdomen even at 4 cm source to detector separation. This instrument is intended for future application in trans-abdominal fetal heart rate detection. © 2008 Springer-Verlag
Three dimensional modeling of axonal microtubules
, Article 2014 21st Iranian Conference on Biomedical Engineering, ICBME 2014, 26 November 2014 through 28 November 2014 ; November , 2014 , Pages 298-302 ; 9781479974177 (ISBN) ; Shamloo, A ; Sharif University of Technology
Institute of Electrical and Electronics Engineers Inc
2014
Abstract
Axon is a filament in neuronal system and axonal microtubules are bundles in axons. In axons, microtubules are coated with microtubule-associated protein tau, a natively unfolded profuse filamentous protein in the central nervous system. These proteins are responsible for the cross-linked structure of the axonal microtubule bundles. Through complimentary dimerization with other tau proteins, bridges are formed to nearby microtubules to create bundles. The transverse reinforcement of microtubules by cross-linking to the cytoskeleton has been shown to enhance their ability to bear compressive loads. Though microtubules are conventionally regarded as bearing compressive loads, in certain...
Thickness as an important parameter in designing vascular grafts
, Article 2014 21st Iranian Conference on Biomedical Engineering, ICBME 2014 ; Nov , 2014 , p. 40-43 ; Shamloo, A ; Samani, S. A ; Dodel, M ; Sharif University of Technology
Abstract
The main goal of this study is to investigate the role of vascular graft thickness in wall stress gradient in anastomosis region. Atherosclerosis is a common heart disease causes high mortality rates every year. The gold standard treatment of atherosclerosis is replacing with autologous vein extracted from patient's body. Since proper autologous vein is limited, researchers have made efforts to achieve compliance engineered blood vessels. Mechanical stress has great effect on both smooth muscle cells and endothelial cells and it is considered as a stimulus in plaque formation. In this study, we evaluate the role of thickness in wall stress of anastomosis region. For this purpose, two...
Thickness as an important parameter in designing vascular grafts
, Article 2014 21st Iranian Conference on Biomedical Engineering, ICBME 2014, 26 November 2014 through 28 November 2014 ; November , 2014 , Pages 40-43 ; 9781479974177 (ISBN) ; Shamloo, A ; Samani, S. A ; Dodel, M ; Sharif University of Technology
Institute of Electrical and Electronics Engineers Inc
2014
Abstract
The main goal of this study is to investigate the role of vascular graft thickness in wall stress gradient in anastomosis region. Atherosclerosis is a common heart disease causes high mortality rates every year. The gold standard treatment of atherosclerosis is replacing with autologous vein extracted from patient's body. Since proper autologous vein is limited, researchers have made efforts to achieve compliance engineered blood vessels. Mechanical stress has great effect on both smooth muscle cells and endothelial cells and it is considered as a stimulus in plaque formation. In this study, we evaluate the role of thickness in wall stress of anastomosis region. For this purpose, two...
The effects of trochlear groove geometry on patellofemoral joint stability - A computer model study
, Article Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine ; Volume 222, Issue 1 , 2008 , Pages 75-88 ; 09544119 (ISSN) ; Farahmand, F ; Meghdari, A ; Sharif University of Technology
2008
Abstract
The effect of the variation in the femoral groove geometry on patellofemoral joint stability was studied using a two dimensional transverse plane model with deformable articular surfaces. The femoral and patellar bony structures were modelled as rigid bodies with their profiles expressed by splines. The articular cartilage was discretized into compression springs, distributed along the femoral and patellar profiles, based on the rigid-body spring model. The medial and lateral retinacula were modelled as linear tensile springs, and the quadriceps muscles and patellar tendon as strings with known tension. The anatomical data were obtained from the transverse plane magnetic resonance images of...
The effects of thymus plant extracts on single breast cancer cell morphology in the microfluidic channel
, Article 2018 IEEE EMBS Conference on Biomedical Engineering and Sciences, IECBES 2018, 3 December 2018 through 6 December 2018 ; 2019 , Pages 647-651 ; 9781538624715 (ISBN) ; Mansor, M. A ; Alsadat Rad, M ; Soo-Beng Khoo, A ; Ahmad, M ; Marzuki, M ; Physiological Measurement; Sarawak Convention Bureau ; Sharif University of Technology
Institute of Electrical and Electronics Engineers Inc
2019
Abstract
Microfluidics based systems could be useful for drug discovery as they allow for miniaturization and could potentially be run as multiple parallel cell based assays. Such miniaturization allows assays at single cell level and reduces the amount of test material needed, which, in the case of natural product extracts, simplifies the preparation. Thyme species extracts have been reported to show some promising anti-cancer effects. In the present work, we used a microfluidics based system to study the effects of Thymus kotschyanusm Boiss plant extract on two human breast cancer cells lines which are MDA-MB-231 and MCF-7. For better understanding a single cancer cell death mechanism and a flow...
The effects of postural difficulty conditions on variability of joint kinematic patterns during sit to stand task in normals and patients with non-specific chronic low back pain
, Article 2011 1st Middle East Conference on Biomedical Engineering, MECBME 2011, 21 February 2011 through 24 February 2011, Sharjah ; 2011 , Pages 300-303 ; 9781424470006 (ISBN) ; Negahban, H ; Yazdi, M. J. S ; Salehi, R ; Mehravar, M ; Parnianpour, M ; Sharif University of Technology
2011
Abstract
Sit to stand (STS) is one of the most important activities of daily living that is shown to be affected in low back pain (LBP) patients. It requires a fundamental coordination action among all segments (DOFs) of the body in order to control important performance variables such as body's center of mass (CM) within base of support (BOS). In this study, possible differences in joint coordination and variability patterns between chronic LBP and healthy control subjects were investigated during STS task. Eleven adults with nonspecific chronic LBP and 12 healthy controls were recruited in the study. The participants performed the task in 3 exerimental conditions including: rigid surface, open eyes...
The dynamic analysis of a novel dental implant with a viscoelastic internal damping layer
, Article 2010 17th Iranian Conference of Biomedical Engineering, ICBME 2010 - Proceedings, 3 November 2010 through 4 November 2010 ; November , 2010 ; 9781424474844 (ISBN) ; Firoozbakhsh, K ; Ghanati, G ; Isfahan University of Medical Sciences; Iranian Society of Biomedical Engineering; Medical Image and Signal Processing Research Center (MISP) ; Sharif University of Technology
2010
Abstract
Conventional tooth implants lacks the damping prosperities of the periodontal ligaments (PDL) compound. It may therefore, disrupts the natural function of implant and leads to excessive stress and strain in jaw bone. Our new proposed implant has the viscoelastic properties needed to overcome such difficulties. A three dimensional finite element model of modified implant was developed and was subjected to dynamic loading condition. Our results so far indicate that the use of a class of material exhibiting viscoelastic behaviour as a damping layer can reduce the peak stress and displacement deduced from cyclic and impact loads. The stress distribution becomes more uniform in the alveolar crest...
The dilemma of BME research projects in developing countries: a case study
, Article Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference ; Volume 2011 , 2011 , Pages 3631-3635 ; 1557170X (ISSN) ; Attar, H. M ; Sharif University of Technology
2011
Abstract
Researchers are faced with huge challenges when undertaking BME research projects in developing countries. Various administrative, technical, economic and even cultural barriers have to be overcome whereas the quality and quantity of the output has to be comparable with the developed world in order to make results publishable. This paper uses a real project context to highlight the major problems and the necessity of a holistic approach which would take into consideration all stakeholders interests. It is only by tackling problems such as relationship between academia-industry and administration efficiency at their root that significant progress can be achieved
System identification for characterization of the frequency response of an 'open-source' biomedical circuit
, Article IECBES 2014, Conference Proceedings - 2014 IEEE Conference on Biomedical Engineering and Sciences: "Miri, Where Engineering in Medicine and Biology and Humanity Meet", 8 December 2014 through 10 December 2014 ; 2015 , Pages 225-229 ; 9781479940844 (ISBN) ; Mohd Ali, M. A. B ; Sharif University of Technology
Abstract
In this paper, system identification techniques are applied to accurately characterize the frequency behavior of a commercially available but with unknown characteristics of a photoplethysmography (under the commercial name of Pulse Sensor). Although claimed to be open-source, the electronic schematic of this device does not allow for a full characterization of it. Therefore a second order auto-regressive with exogenous input model has been employed to find the frequency response of this system. An optical excitation circuit was developed to send a pseudo-random signal to the Pulse Sensor. Results show that the model is able to reproduce the output with a fitness of 89.7 %. The obtained...
SVD analysis of dynamic properties for fatigue loaded intervertebral disc
, Article 2011 1st Middle East Conference on Biomedical Engineering, MECBME 2011, 21 February 2011 through 24 February 2011, Sharjah ; 2011 , Pages 32-36 ; 9781424470006 (ISBN) ; Malik, A. S ; Wang, J. L ; Parnianpour, M ; Sharif University of Technology
2011
Abstract
This paper uses singular value decomposition (SVD) for studying the dynamic properties of fatigue-loaded intervertebral disc. Previously, this problem had been addressed using mathematical models of using mass, spring and damper or based on poroelastic theory. This paper utilizes the signal processing approach and attempts to describe SVD based feature that can be an indicator for change in behavioral performance of the intervertebral disc warning the occurrence of temporary or permanent change in the structure or abnormality in behavior. The results are encouraging; however, further validation is required with more data
Superparamagnetic nanoparticles for epilepsy detection
, Article World Congress on Medical Physics and Biomedical Engineering, 2015, 7 June 2015 through 12 June 2015 ; Volume 51 , June , 2015 , Pages 1237-1240 ; 16800737 (ISSN) ; 9783319193878 (ISBN) ; Shamloo, A ; Alasty, A ; Ghafar Zadeh, E ; Jaffray D. A ; Sharif University of Technology
Springer Verlag
2015
Abstract
Epilepsy is the most common neurological disorder that is known with uncontrolled seizure. Around 30% of patients with epilepsy resist to all forms of medical treatments and therefore, the removal of epileptic brain tissue is the only solution to get these patients free from chronical seizures. The precise detection of an epileptic zone is key to its treatment. In this paper, we propose a method of epilepsy detection using brain magnetic field. The possibility of superparamagnetic nanoparticle (SPMN) as sensors for the detection of the epileptic area inside the brain is investigated. The aggregation of nanoparticles in the weak magnetic field of epileptic brain is modeled using potential...
Steered molecular dynamic simulation approaches for computing the blood brain barrier (BBB) diffusion coefficient
, Article IFMBE Proceedings ; Volume 51 , 2015 , Pages 1699-1703 ; 16800737 (ISSN) ; 9783319193878 (ISBN) ; Shamloo, A ; Alasti, A ; Zadeh, E. G ; Jaffray D. A ; Sharif University of Technology
Springer Verlag
2015
Abstract
In the recent years a great attention of research deals with different physical and biological aspects of the BBB structure, a robust shield that separates the blood and brain, a recent research held by the authors of this paper has focused on figuring out computing the diffusion coefficient of endothelial cell membrane. In this study, the major efforts have been concentrated on calculating a standardized measure for the amount of permeability and diffusion of this barrier. As a result, this work is dedicated to molecular dynamics (MD) simulation of calculating the interaction force between nano-particle and BBB membrane. data is recorded by using steered molecular dynamics simulation and...
State of the art review on design and manufacture of hybrid biomedical materials: Hip and knee prostheses
, Article Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine ; Volume 231, Issue 9 , 2017 , Pages 785-813 ; 09544119 (ISSN) ; Farahmand, F ; Sharif University of Technology
Abstract
The trend in biomaterials development has now headed for tailoring the properties and making hybrid materials to achieve the optimal performance metrics in a product. Modern manufacturing processes along with advanced computational techniques enable systematical fabrication of new biomaterials by design strategy. Functionally graded materials as a recent group of hybrid materials have found numerous applications in biomedical area, particularly for making orthopedic prostheses. This article, therefore, seeks to address the following research questions: (RQ1) What is the desired structure of orthopedic hybrid materials? (RQ2) What is the contribution of the literature in the development of...
Speckle noise reduction of ultrasound images using M-band wavelet transform and wiener filter in a homomorphic framework
, Article 1st International Conference on BioMedical Engineering and Informatics, BMEI 2008, Sanya, Hainan, 27 May 2008 through 30 May 2008 ; Volume 2 , 2008 , Pages 510-515 ; 9780769531182 (ISBN) ; Shamsollahi, M. B ; Sharif University of Technology
2008
Abstract
In this paper we make use of M-band discrete wavelet transform (MDWT) and Wiener filter for speckle noise suppression of ultrasound images. Assuming multiplicative model for speckle noise, by applying logarithmic transform to noisy observation we convert multiplicative noise to additive one. Then, speckle noise can be reduced by taking the M-band wavelet transform of log-transformed observation and employing an adaptive thresholding technique. In order to improve the performance of this denosing approach, we propose a preprocessing stage which exploits Wiener filtering. Through this stage logtransformed observation is separated into two images and then each of these two images is denoised...
Sparse representation-based super-resolution for diffusion weighted images
, Article 21st Iranian Conference on Biomedical Engineering, ICBME ; 26-28 November , 2014 , pp. 12-16 ; ISBN: 9781479974177 ; Fatemizadeh, E ; Soltanian-Zadeh, H ; Sharif University of Technology
Abstract
Diffusion weighted imaging (DWI) is a non-invasive method for investigating the brain white matter structure. It can be used to evaluate fiber bundles in the brain. However, clinical acquisitions are often low resolution. This paper proposes a method for improving the resolution using sparse representation. In this method a non-diffusion weighted image (bO) is utilized to learn the patches and then diffusion weighted images are reconstructed based on the trained dictionary. Our method is compared with bilinear, nearest neighbor and bicubic interpolation methods. The proposed method shows improvement in terms of Peak Signal-to-Noise Ratio (PSNR) and Structural SIMilarity (SSIM)