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Organocopper-based magnetically recoverable and reusable nanocatalyst for efficient synthesis of novel 1,2,3-triazole-based sulfonamides in green medium
, Article Research on Chemical Intermediates ; Volume 44, Issue 1 , 2018 , Pages 601-612 ; 09226168 (ISSN) ; Sadighian, H ; Arabgari, M ; Mirjafary, Z ; Ayati, S. E ; Najafi, E ; Matloubi Moghaddam, F ; Sharif University of Technology
Springer Netherlands
2018
Abstract
Abstract: We report robust green synthesis of novel 1,2,3-triazole-based sulfonamides bearing different motifs such as fluorine under click conditions in presence of a copper-based magnetically recoverable and reusable heterogeneous nanocatalyst. The organocopper catalyst at 0.5 mol.% was highly recyclable (up to five times) when recovered using an external magnet without significant loss in catalytic activity. The mild reaction conditions and excellent yields (69–95 %) make this protocol an attractive method for efficient synthesis of the title compounds. The structure of product 3a was determined by Röntgen crystal structure analysis. Graphical Abstract: [Figure not available: see...