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The effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on the cognitive and motor functions in rodents: A systematic review and meta-analysis
, Article Neuroscience and Biobehavioral Reviews ; Volume 140 , 2022 ; 01497634 (ISSN) ; Abbaszadeh, M ; Ghazizadeh, A ; Sharif University of Technology
Elsevier Ltd
2022
Abstract
Memory and motor deficits are commonly identified in Parkinson's disease (PD). 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is transformed to MPP+ via monoamine oxidase B (MAOB), which causes oxidative stress and destroys dopaminergic (DA) neurons in substantia nigra pars compacta (SNc) and is widely used to create animal models of PD. However, to-date, a comprehensive analysis of the MPTP effects on various aspects of PD does not exist. Here, we provide a systematic review and meta-analysis on the MPTP effects on memory and motor functions by analyzing 51 studies on more than one thousand animals mainly including rats and mice. The results showed that in addition to motor functions...
Apathy exacerbates postural control impairments in stroke survivors: The potential effects of cognitive dual-task for improving postural control
, Article Neuropsychologia ; Volume 174 , 2022 ; 00283932 (ISSN) ; Mehdizadeh, H ; Azad, A ; Cheraghifard, M ; Jamali, S ; Davoudi, M ; Shokouhyan, S. M ; Taghizadeh, G ; Sharif University of Technology
Elsevier Ltd
2022
Abstract
Apathy is a stressor and debilitating common condition for both stroke survivors and their caregivers. However, its effects on the postural control of these patients have not yet been investigated. Improved postural stability through withdrawing attention from postural control by concurrent cognitive task (i.e. dual-task condition) has been reported previously, but the effect of apathy, as a confounding factor, remains unknown. This study aimed to examine the effects of apathy and dual-task condition on postural control of chronic stroke survivors from biomechanical and neurophysiological perspectives. Twenty non-apathetic stroke survivors, 20 apathetic stroke survivors, and 20 sex-, age-,...
Validation of the driver's angry thoughts questionnaire (DATQ) in a sample of professional drivers in iran
, Article IATSS Research ; Volume 46, Issue 3 , 2022 , Pages 370-379 ; 03861112 (ISSN) ; Nassiri, H ; Sullman, M. J. M ; Sharif University of Technology
Elsevier B.V
2022
Abstract
Aggressive driving has emerged as one of the most studied behaviors in the traffic safety field, due to its association with the odds of motor vehicle crashes and especially fatal crashes. Previous research has investigated the situations which provoke anger while driving, as well as the emotional (anger) and behavioral (aggression) aspects of aggressive driving. However, surprisingly the cognitive aspects of aggressive driving have largely been neglected. This study investigated the psychometric properties of the short-forms of the Driver's Angry Thoughts Questionnaire (DATQ) and the Driving Anger Expression Inventory (DAX) in a sample of professional drivers. Furthermore, the study aimed...
Promoting the adoption of residential water conservation behaviors as a preventive policy to sustainable urban water management
, Article Journal of Environmental Management ; Volume 313 , 2022 ; 03014797 (ISSN) ; Tabesh, M ; Yazdanpanah, M ; Zobeidi, T ; Raoof, M. A ; Sharif University of Technology
Academic Press
2022
Abstract
As concerning with water insecurity driven by water scarcity threatens the lives and livelihoods of humanity worldwide, urban water demand management is focused on promoting residential water conservation behaviors (WCBs) as a critical policy response to water scarcity. However, urban water conservation initiatives cannot be successful unless households involve in residential WCBs voluntarily by adopting water curtailment and/or water-efficiency actions. Thus, understanding motivations and mechanisms underlying accepting these two types of WCBs and interpreting their distinctions are primary policy considerations to make sustainable water consumption behaviors. Hence, the purpose of this...
Corrigendum: Immersive media-based tourism emerging challenge of VR addiction among generation Z (Front. Public Health, (2022), 10, 833658, 10.3389/fpubh.2022.833658)
, Article Frontiers in Public Health ; Volume 10 , 2022 ; 22962565 (ISSN) ; Zhou, R ; Gholizadeh, A ; Asmi, F ; Sharif University of Technology
Frontiers Media S.A
2022
Abstract
In the published article, there was an error regarding the affiliations for Saba Saneinia. As well as having affiliation 1, she should also have Key Laboratory of Immersive Media Technology (Anhui Xinhua Media Co, Ltd.), Ministry of Culture and Tourism, Hefei, China. In the published article, there was an error regarding the affiliations for Rongting Zhou. As well as having affiliations 2, he should also have Key Laboratory of Immersive Media Technology (Anhui Xinhua Media Co, Ltd.), Ministry of Culture and Tourism, Hefei, China. In the published article, there was an error regarding the affiliations for Fahad Asmi. As well as having affiliations 2, he should also have Key Laboratory of...
Symmetric and asymmetric bimanual coordination and freezing of gait in Parkinsonian patients in drug phases
, Article Annals of the New York Academy of Sciences ; Volume 1511, Issue 1 , 2022 , Pages 244-261 ; 00778923 (ISSN) ; Azad, A ; Akbarfahimi, M ; Behzadipour, S ; Taghizadeh, G ; Sharif University of Technology
John Wiley and Sons Inc
2022
Abstract
Freezing of gait (FOG) is a debilitating symptom in patients with Parkinson's disease (PD), which may be associated with motor control impairments in tasks other than gait. This study aimed to examine whether symmetric and asymmetric bimanual coordination is impaired in PD with FOG (PD +FOG) patients and whether dual-task and drug phases may affect bimanual coordination in these patients. Twenty PD +FOG patients, 20 PD patients without FOG (PD –FOG) performed symmetric and asymmetric functional bimanual tasks (reach to and pick up a box and open a drawer to press a pushbutton inside it, respectively) under single-task and dual-task conditions. PD patients were evaluated during on- and...
Behavior of olfactory-related frontal lobe oscillations in Alzheimer's disease and MCI: A pilot study
, Article International Journal of Psychophysiology ; Volume 175 , 2022 , Pages 43-53 ; 01678760 (ISSN) ; Aghajan, H ; Vahabi, Z ; Afzal, A ; Sedghizadeh, M. J ; Sharif University of Technology
Elsevier B.V
2022
Abstract
Slow-gamma (35-45 Hz) phase synchronization and the coupling between slow-gamma and low-frequency theta oscillations (4–8 Hz) are closely related to memory retrieval and cognitive functions. In this pilot study, we assess the Phase Amplitude Coupling (PAC) between theta and slow-gamma oscillatory bands and the quality of synchronization in slow-gamma oscillations using Phase Locking Value (PLV) on EEG data from healthy individuals and patients diagnosed with amnestic Mild Cognitive Impairment (aMCI) and Alzheimer's Disease (AD) during an oddball olfactory task. Our study indicates noticeable differences between the PLV and PAC values corresponding to olfactory stimulation in the three groups...
Immersive media-based tourism emerging challenge of VR addiction among generation Z
, Article Frontiers in Public Health ; Volume 10 , 2022 ; 22962565 (ISSN) ; Zhou, R ; Gholizadeh, A ; Asmi, F ; Sharif University of Technology
Frontiers Media S.A
2022
Abstract
The virtual reality (VR) applications in entertainment and tourism industry have become growingly intense among generation Z. Interestingly, some pilot research on tourism studied concluded the positive impact of its flow experience on adoption of VR tourism, which is also driving the risk of immersive addictive. In the context of tourism and information and communication technology (ICT)-based innovation, there is a lack of immersive addictive behavior (IAB)-related literature. In addition, during the currently ongoing pandemic crisis, VR technology has gained particular importance in the tourism industry among generation Z. The present venture underlines the mechanism of IAB, investigates...
Utilizing social virtual reality robot (V2R) for music education to children with high-functioning autism
, Article Education and Information Technologies ; Volume 27, Issue 1 , 2022 , Pages 819-843 ; 13602357 (ISSN) ; Taheri, A ; Mokhtari, M ; Shariati, A ; Heidari, R ; Meghdari, A ; Alemi, M ; Sharif University of Technology
Springer
2022
Abstract
Virtual Reality (VR) technology is a growing technology that has been used in various fields of psychology, education, and therapy. One group of potential users of VR are children with autism who need education and have poor social interactions; this technology could help them improve their social skills through real-world simulation. In this study, we evaluated the feasibility of conducting virtual music education programs with automatic assessment system for children with autism at treatment/research centers without the need to purchase a robot, resulting in the possibility of offering schedules on a larger scale and at a lower cost. Intervention sessions were conducted for five children...
Identifying brain functional connectivity alterations during different stages of Alzheimer’s disease
, Article International Journal of Neuroscience ; Volume 132, Issue 10 , 2022 , Pages 1005-1013 ; 00207454 (ISSN) ; Fatemizadeh, E ; Motie Nasrabadi, A ; Sharif University of Technology
Taylor and Francis Ltd
2022
Abstract
Purpose: Alzheimer's disease (AD) starts years before its signs and symptoms including the dementia become apparent. Diagnosis of the AD in the early stages is important to reduce the speed of brain decline. Aim of the study: Identifying the alterations in the functional connectivity of the brain during the disease stages is among the main important issues in this regard. Therefore, in this study, the changes in the functional connectivity during the AD stages were analyzed. Materials and methods: By employing the functional magnetic resonance imaging (fMRI) data and graph theory, weighted undirected graphs of the whole-brain and default mode network (DMN) network were investigated...
Aggressive driving: Do driving overconfidence and aggressive thoughts behind the wheel, drive professionals off the road?
, Article Transportation Research Part F: Traffic Psychology and Behaviour ; Volume 79 , 2021 , Pages 170-184 ; 13698478 (ISSN) ; Nassiri, H ; Sharif University of Technology
Elsevier Ltd
2021
Abstract
Aggressive driving has emerged as one of the most studied behaviors in the traffic psychology context due to its association with odds of motor vehicle crashes (MVCs) and especially fatal ones. Nevertheless, behavioral (aggression) and affective (anger) aspects of aggressive driving have been deeply studied; its cognitive part hasn't gained much attention; However, its role in understanding the process of aggression and designing interventions couldn't be neglected. This research investigated the contribution of overconfidence (as the driver's cognitive bias), aggressive thoughts, driver's aggression, and risk perception in driver's performance and the number of self-reported active...
Anxiety and cognitive load affect upper limb motor control in Parkinson's disease during medication phases
, Article Annals of the New York Academy of Sciences ; Volume 1494, Issue 1 , 2021 , Pages 44-58 ; 00778923 (ISSN) ; Mehdizadeh, H ; Azad, A ; Mehdizadeh, M ; Reyhanian, E ; Saberi, Z. S ; Meimandi, M ; Soltanzadeh, A ; Roohi Azizi, M ; Vasaghi Gharamaleki, B ; Parnianpour, M ; Khalaf, K ; Taghizadeh, G ; Sharif University of Technology
John Wiley and Sons Inc
2021
Abstract
Anxiety is among the most debilitating nonmotor symptoms of Parkinson's disease (PD). This study aimed to determine how PD patients with low and high levels of anxiety (LA-PD and HA-PD, respectively) compare with age- and sex-matched controls at the level of motor control of reach-to-grasp movements during single- and dual-task conditions with varying complexity. Reach-to-grasp movement kinematics were assessed in 20 LA-PD, 20 HA-PD, and 20 sex- and age-matched healthy controls under single- as well as easy and difficult dual-task conditions. Assessment of PD patients was performed during both the on- and off-drug phases. The results obtained during dual-task conditions reveal deficits in...
Evaluating a new verbal working memory-balance program: a double-blind, randomized controlled trial study on Iranian children with dyslexia
, Article BMC Neuroscience ; Volume 22, Issue 1 , 2021 ; 14712202 (ISSN) ; Behzadipour, S ; Pourghayoomi, E ; Joghataei, M. T ; Shirazi, E ; Fawcett, A. J ; Sharif University of Technology
BioMed Central Ltd
2021
Abstract
Background: It is important to improve verbal Working Memory (WM) in reading disability, as it is a key factor in learning. There are commercial verbal WM training programs, which have some short-term effects only on the verbal WM capacity, not reading. However, because of some weaknesses in current verbal WM training programs, researchers suggested designing and developing newly structured programs that particularly target educational functions such as reading skills. In the current double-blind randomized clinical trial study, we designed a new Verbal Working Memory-Balance (VWM-B) program which was carried out using a portable robotic device. The short-term effects of the VWM-B program,...
Allergic rhinitis impairs working memory in association with drop of hippocampal – Prefrontal coupling
, Article Brain Research ; Volume 1758 , 2021 ; 00068993 (ISSN) ; Ghazvineh, S ; Nazari, M ; Dehdar, K ; Garousi, M ; Zare, M ; Tabasi, F ; Jamaati, H ; Salimi, A ; Barkley, V ; Mirnajafi Zadeh, J ; Raoufy, M. R ; Sharif University of Technology
Elsevier B.V
2021
Abstract
Allergic rhinitis (AR) is a chronic inflammatory disease frequently associated with a deficit in learning and memory. Working memory is an important system for decision making and guidance, which depends on interactions between the ventral hippocampus (vHipp) and the prelimbic prefrontal cortex (plPFC). It is still unclear whether AR influences the activity and coupling of these brain areas, which consequently may impair working memory. The current study aimed to examine alterations of the vHipp-plPFC circuit in a rat model of AR. Our results show decreased working memory performance in AR animals, accompanied by a reduction of theta and gamma oscillations in plPFC. Also, AR reduces...
A close look at the imitation performance of children with autism and typically developing children using a robotic system
, Article International Journal of Social Robotics ; Volume 13, Issue 5 , 2021 , Pages 1125-1147 ; 18754791 (ISSN) ; Meghdari, A ; Mahoor, M. H ; Sharif University of Technology
Springer Science and Business Media B.V
2021
Abstract
Deficit in imitation skills is one of the core symptoms of children with Autism Spectrum Disorder (ASD). In this study, we have tried to look closer at the body gesture imitation performance of 20 participants with autism, i.e. ASD group, and 20 typically developing subjects, i.e. TD group, in a set of robot-child and human-child gross imitation tasks. The results of manual scoring by two specialists indicated that while the TD group showed a significantly better imitation performance than the ASD group during the tasks, both ASD and TD groups performed better in the human-child mode than the robot-child mode in our experimental setup. Next, to introduce an automated imitation assessment...
Impacts of using a social robot to teach music to children with low-functioning autism
, Article Paladyn ; Volume 12, Issue 1 , 2021 , Pages 256-275 ; 20814836 (ISSN) ; Shariati, A ; Heidari, R ; Shahab, M ; Alemi, M ; Meghdari, A ; Sharif University of Technology
De Gruyter Open Ltd
2021
Abstract
This article endeavors to present the impact of conducting robot-assisted music-based intervention sessions for children with low-functioning (LF) autism. To this end, a drum/xylophone playing robot is used to teach basic concepts of how to play the instruments to four participants with LF autism during nine educational sessions. The main findings of this study are compared to similar studies conducted with children with high-functioning autism. Our main findings indicated that the stereotyped behaviors of all the subjects decreased during the course of the program with an approximate large Cohen’s d effect size. Moreover, the children showed some improvement in imitation, joint attention,...
Exploring cognitive activation writing strategies among iranian english language teachers
, Article Language Related Research ; Volume 12, Issue 5 , 2021 , Pages 433-462 ; 23223081 (ISSN) ; Hassanzadeh, M ; Masoudi, M ; Sharif University of Technology
Tarbiat Modares University
2021
Abstract
In order to engage students in higher-level thinking, cognitive activation (CA) strategies have been advanced and utilized in mathematics. CA develops when learners are challenged, confronted with conflicts, asked to think and explain clearly on their learning, and realize connections between new and previous content. Extending the theme to English language teaching (ELT), this study investigated Iranian English language teachers‟ knowledge and practice of cognitive activation writing strategies (CAWS). In so doing, a model was proposed based on a questionnaire that was developed and validated in the present study. Through this scale, knowledge and practice of CAWS by 213 English as a...
Exploring cognitive activation writing strategies among iranian english language teachers
, Article Language Related Research ; Volume 12, Issue 5 , 2021 , Pages 433-462 ; 23223081 (ISSN) ; Hassanzadeh, M ; Masoudi, M ; Sharif University of Technology
Tarbiat Modares University
2021
Abstract
In order to engage students in higher-level thinking, cognitive activation (CA) strategies have been advanced and utilized in mathematics. CA develops when learners are challenged, confronted with conflicts, asked to think and explain clearly on their learning, and realize connections between new and previous content. Extending the theme to English language teaching (ELT), this study investigated Iranian English language teachers‟ knowledge and practice of cognitive activation writing strategies (CAWS). In so doing, a model was proposed based on a questionnaire that was developed and validated in the present study. Through this scale, knowledge and practice of CAWS by 213 English as a...
Overexpression of protein kinase Mζ in the hippocampus mitigates alzheimer's disease-related cognitive deficit in rats
, Article Brain Research Bulletin ; Volume 166 , 2021 , Pages 64-72 ; 03619230 (ISSN) ; Roosta Azad, R ; Motamedi, F ; Mirzapour Delavar, H ; Ghasemi, S ; Aliakbari, S ; Pourbadie, H. G ; Sharif University of Technology
Elsevier Inc
2021
Abstract
Accumulation of amyloid beta (Aβ) soluble forms in the cerebral parenchyma is the mainstream concept underlying memory deficit in the early phase of Alzheimer's disease (AD). PKMζ plays a critical role in the maintenance of long-term memory. Yet, the role of this brain-specific enzyme has not been addressed in AD. We examined the impact of hippocampal PKMζ overexpression on AD-related memory impairment in rats. Oligomeric form of Aβ (oAβ) or vehicle was bilaterally microinjected into the dorsal hippocampus of male Wistar rats under stereotaxic surgery. One week later, 2 μl of lentiviral vector (108 T.U. / ml.) encoding PKMζ genome was microinjected into the dorsal hippocampus. Seven days...
A Fast Soft Decision Algorithm for Cooperative Spectrum Sensing
, Article IEEE Transactions on Circuits and Systems II: Express Briefs ; Volume 68, Issue 1 , 2021 , Pages 241-245 ; 15497747 (ISSN) ; Fakharzadeh, M ; Sharif University of Technology
Institute of Electrical and Electronics Engineers Inc
2021
Abstract
Hidden Primary User problem caused by fading and shadowing severely affects the detection rate of the cognitive radio systems with a single spectrum sensor. Cooperative Spectrum Sensing has been introduced to tackle this problem by using the spatial diversity of spectrum sensors. It is shown that the use of soft decision algorithms in fusion center has a better performance than hard decision algorithms. The problem of soft decision based on sensor measurements perfectly matches the Machine Learning paradigm. In this brief, a novel fast soft decision algorithm is proposed based on Machine Learning theory for wideband Cooperative Spectrum Sensing, which finds a decision boundary to classify...