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diagnostic-applications
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Nonrigid registration of breast MR images using residual complexity similarity measure
, Article Iranian Conference on Machine Vision and Image Processing, MVIP, Zanjan ; Sept , 2013 , Pages 241-244 ; 21666776 (ISSN); 9781467361842 (ISBN) ; Ghaffari, A ; Fatemizadeh, E ; Sharif University of Technology
IEEE Computer Society
2013
Abstract
Elimination of motion artifact in breast MR images is a significant issue in pre-processing step before utilizing images for diagnostic applications. Breast MR Images are affected by slow varying intensity distortions as a result of contrast agent enhancement. Thus a nonrigid registration algorithm considering this effect is needed. Traditional similarity measures such as sum of squared differences and cross correlation, ignore the mentioned distortion. Therefore, efficient registration is not obtained. Residual complexity is a similarity measure that considers spatially varying intensity distortions by maximizing sparseness of the residual image. In this research, the results obtained by...
Design and fabrication of a two-phase diamond nanoparticle aided fast PCR device
, Article Analytica Chimica Acta ; Volume 1068 , 2019 , Pages 28-40 ; 00032670 (ISSN) ; Ghazimirsaeed, E ; Shamloo, A ; Sharif University of Technology
Elsevier B.V
2019
Abstract
Polymerase Chain Reaction (PCR) is an important and prevalent technique in biotechnology because of its crucial role in cloning DNA fragments and diagnostic applications. In the present study, a high-throughput two-phase PCR device is designed and fabricated which utilizes a serpentine microchannel together with a spiral structure. The former is for the droplet-generation and mixing and the latter is for the thermal cycling process. Moreover, the effect of diamond nanoparticles (diamondNP) on the performance of PCR is also investigated while using commercial PCR devices and the fabricated PCR device designed in this study. Using numerical simulation, it is shown that within the simple and...
Emerging phospholipid nanobiomaterials for biomedical applications to lab-on-a-chip, drug delivery, and cellular engineering
, Article ACS Applied Bio Materials ; 2021 ; 25766422 (ISSN) ; Rabiee, N ; Ahmadi, S ; Jahangiri, S ; Sajadi, S. M ; Akhavan, O ; Saeb, M. R ; Kwon, W ; Kim, M ; Hahn, S. K ; Sharif University of Technology
American Chemical Society
2021
Abstract
The design of advanced nanobiomaterials to improve analytical accuracy and therapeutic efficacy has become an important prerequisite for the development of innovative nanomedicines. Recently, phospholipid nanobiomaterials including 2-methacryloyloxyethyl phosphorylcholine (MPC) have attracted great attention with remarkable characteristics such as resistance to nonspecific protein adsorption and cell adhesion for various biomedical applications. Despite many recent reports, there is a lack of comprehensive review on the phospholipid nanobiomaterials from synthesis to diagnostic and therapeutic applications. Here, we review the synthesis and characterization of phospholipid nanobiomaterials...