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diterpenoid
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A lupane triterpenoid and other constituents of Salvia eremophila
, Article Natural Product Research ; Volume 26, Issue 21 , 2012 , Pages 2045-2049 ; 14786419 (ISSN) ; Moghaddam, F. M ; Esmaeili, M. A ; Amin, G ; Sharif University of Technology
2012
Abstract
Phytochemical investigation of the aerial parts of Salvia eremophila led to the isolation of a lupane triterpenoid, 3β, 20-dihydroxylupane-28-oic acid (1), together with eight other compounds, comprising three diterpene, two triterpene, two flavonoids and a steroidal glucoside. Their structures were elucidated by interpretation of their one-dimensional and two-dimensional NMR spectra and completed by the analysis of the HRESIMS data. Compounds 1, 2-4 and 8 were evaluated for their cytotoxicities against five human tumour cell lines. Compounds 1 and 3 hold a good potential for use in future studies due to their anti-cancer properties
A simple and efficient total synthesis of (±)-danshexinkun A, a bioactive diterpenoid from Salvia miltiorrhiza
, Article Tetrahedron Letters ; Volume 51, Issue 3 , 2010 , Pages 540-542 ; 00404039 (ISSN) ; Moridi Farimani, M ; Sharif University of Technology
Abstract
An efficient 12-step route for the synthesis of the diterpenoid quinone (±)-danshexinkun A in 23% overall yield from the corresponding highly substituted stilbene using a photocyclization strategy is described