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    Design and Simulation of a Spiral Based Microfluidic Device for Separation of Circulating Tumor Cells Using Tunable Nature of Viscoelastic Fluid

    , M.Sc. Thesis Sharif University of Technology Nouri, Mohammad Moein (Author) ; Saeedi, Mohammad Saeed (Supervisor)
    Abstract
    Nowadays, cancer, which has been mentioned as the disease of the century, is the second leading cause of death throughout the world, and its incidence is constantly increasing. Isolation of circulating tumor cells is one of the most critical steps in diagnosing and controlling cancer progression. Due to the rarity of cancer cells compared to other cells in the blood sample, the isolation process requires optimal and high-precision devices. With the advent of inertial microfluidics, the ability to control the particles movement, the processing of blood samples as quickly and accurately as possible, and the viability of cells with a high percentage, introduced microfluidic systems as a...