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A portable culture chamber for studying the effects of hydrostatic pressure on cellular monolayers
, Article Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science ; 2018 ; 09544062 (ISSN) ; Saidi, M ; Mosadegh, B ; Firoozabadi, B ; Sharif University of Technology
SAGE Publications Ltd
2018
Abstract
Hydrostatic pressure is one of the most fundamental and common mechanical stimuli in the body, playing a critical role in the homeostasis of all organ systems. Kidney function is affected by high blood pressure, namely hypertension, by the increased pressure acting on the glomerular capillary walls. This general effect of hypertension is diagnosed as a chronic disease, but underlying mechanistic causes are still not well understood. This paper reports a portable and adaptive device for studying the effects of hydrostatic pressure on a monolayer of cells. The fabricated device fits within a conventional incubation system and microscope. The effects of various pressures and durations were...
A portable culture chamber for studying the effects of hydrostatic pressure on cellular monolayers
, Article Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science ; Volume 233, Issue 3 , 2019 , Pages 807-816 ; 09544062 (ISSN) ; Saidi, M. S ; Mosadegh, B ; Firoozabadi, B ; Sharif University of Technology
SAGE Publications Ltd
2019
Abstract
Hydrostatic pressure is one of the most fundamental and common mechanical stimuli in the body, playing a critical role in the homeostasis of all organ systems. Kidney function is affected by high blood pressure, namely hypertension, by the increased pressure acting on the glomerular capillary walls. This general effect of hypertension is diagnosed as a chronic disease, but underlying mechanistic causes are still not well understood. This paper reports a portable and adaptive device for studying the effects of hydrostatic pressure on a monolayer of cells. The fabricated device fits within a conventional incubation system and microscope. The effects of various pressures and durations were...