Sharif Digital Repository

One of the main reasons of brain attack is stenosis in Carotid bifurcation. As a result, it's a major field of interest for a large group of scientists including medical doctors and engineers. In the engineering fields a large number of studies have been done on this topic based on Numerical Simulation. As blood boundary conditions in this region strictly depend on the rest of the body's vascular system, the problem is the definition of the boundary condition in this approach. In addition, because of lack of enough hardware sources simulation of the whole blood system is impossible; thus the rest of the system should be simulated based on radical methods with less details. In this project a... 

Let R be a ring with unity, M be a unitary left R-module and I(M)* be the set of all non-trivial submodules of M. The intersection graph of submodules of M, denoted by G(M), is a graph with the vertex set I(M)* and two distinct vertices N and K are adjacent if and only if N\K ̸= 0. We investigate the interplay between the module-theoretic properties of M and the graph-theoretic properties of G(M). We characterize all modules for which the intersection graph of submodules is connected. Also the diameter and the girth of G(M) are determined. We study the clique number and the chromatic number of G(M). Among other results, it is shown that if G(M) is a bipartite graph, then G(M) is a star... 

Co-culture of different cells is necessary for cancer spheroid formation in preclinical drug tests. It is possible to produce thousands of micro-droplets containing different cells, i.e. microcapsules, in a short time, using droplet microfluidics. However the homogeneity of the cell numbers in the droplets has remained as an unsolved problem.Despite the large amount of experimental efforts to reduce the number of undesirable microcapsules, no one tried to utilize the ease of computer aided simulation for investigating different parameters. In this study, we develop a novel method for capturing cell encapsulation using CFD simulations. The effect of the cell suspension inhomogeneity and... 

Conventional two-dimensional photos are images of a three-dimensional scene. In fact, since the recording medium record only the intensity of the incoming light, information about the phase of the light couldn't be recorded and this results in making 2D photos from a real 3D scene.
In this research a mechanism for getting three-dimensional images in endoscopy and laparoscopy by Digital Holography has been designed based on the criteria standards in this field.
 

Nowadays counting small particles and gathering their morphological information is widely used in many fields as medicine, engineering, etc. One of the best examples of this technology is counting and distinguishing different cells which are considered bioparticles. In this thesis a brief review of different particle counting methods is presented. Among these methods flow cytometry technology is chosen, because of its speed and accuracy. In flow cytometry method cells are conducted to the center of a transparent capillary by sheath flow technique; then laser beam is radiated to the cells. The intensity of the light scattered from the cells is used to determine cell type and count. In... 

In this manuscript, we designed and fabricated a novel integrated microfluidic Kidney Nephron-On-Chip. This chip is able to culture cell monolayers under various fluid shear stresses and divert osmotic pressure gradients while imposing four different concentrations of an injected drug on cells. The multi-layer platform consisting of two bubble-trappers to eliminate all unwanted bubbles from the system, a concentration gradient generator to generate four different concentrations of the injected drug, and a membrane-based cell culture chamber caple of providing renal cells with their in-vivo condition. Using colorimetric techniques, the bubble trapper ability was quantified at flow rates up to... 

A Lab-On-a-Chip (LOC) is a device which can integrate one or many laboratory functions on a small chip with millimeters to few square centimeters in size. LOC is a subset of MEMS devices and known as “Micro Total Analysis Systems” (µTAS) as well. LOC technology is closely related to microfluidics which primarily describes the physics, manipulation and study of minute amount of fluids.In this research we tried to simulate the performance of a microfluidic device for counting blood cells to find main factors of it for design and manufacturing. This research has two main sections, hydrodynamics of fluid inside the microchannels and finding electrical performance of designed Coulter counter for... 

Water is the most essential human need and the lack of fresh water soon is one of the biggest problems of mankind. One way to deal with the lack of fresh water is desalination of seawater. Seawater desalination is done by different thermal and membrane methods. In this research, the methods and history of freshwater supply methods and the role of chains in the progress of seawater desalination, and the measures taken in the field of seawater desalination have been investigated. Among the various methods discussed and proposed in this research, it was concluded that reverse osmosis membrane is available and has an acceptable economic efficiency compared to other methods. After choosing the... 

Fretting fatigue damage occurs in contacting components while they are subjected to fluctuating loads and relatively small movement at the same time. In this condition some micro-cracks are created in these components. These micro-cracks will be propagated and cause sudden failure which is accompanied by great human and economic loss. There are many practical applications that are subjected to fretting fatigue, such as bolted and riveted connections, bearing shafts, blade-disk attachment in gas turbines, aero-engine splined couplings, cable connections and etc. Fretting fatigue failure process can be divided into two portions of crack initiation and propagation. It is very difficult, to... 

Injection of acid into the carbonate rock dissolves the rock, and the porous medium is constantly changing. As a result, the boundaries between the acid and the porous medium, which are in fact the interface between the solid phase and the liquid phase, are constantly changing. Therefore, on the issue of acid injection into carbonate rock, we are facing dynamic boundary conditions. Also, due to the simultaneous solution of transfer and reaction phenomena, modeling acid injection into carbonate rock faces many challenges.In such problems, the ALE method, which is a combination of the best features of the Lagrangian method and the Eulerian method, offers a very precise solution and is used as... 

Additive manufacturing (AM), also known as Rapid prototyping or D printing, is a new technology for the manufacturing of the physical parts through an additive manner. In the AM process, the orientation pattern of the part is one of the most important factors that significantly affects the product properties such as the build time, the surface roughness, the mechanical strength, the wrinkling, and the amount of support material. The build time and the surface roughness are the more imperative criteria than others that can be considered to find the optimum orientation of parts. In this research, Two method is used to optimize part build orientation (PBO). In the first method a new combined... 

In this project an optimized and robust orientation estimation method using IMU and magnetic sensors is presented. Magnetic distortion effects in orientation estimation is also one of the main purposes. Proposed sensor fusion algorithm is based on a complementary filter which provides a quaternion estimation as the algebraic solution of a system from inertial/magnetic observations. To develop the basic sensor fusion algorithm some procedures including a simple calculation to deal better with non-gravitational accelerations, decrease the effect of magnetometer in the presence of distortions and online gyroscope bias estimation is added. Also, a method for classification the different types of... 

In this dissertation we aim to survey the concepts and results concerning Total Domination Set. Consider graph G = (V;E). Let S be a subset of V . S is Total Domination Set in G if every vertex in V is adjacent to at least one vertex in S.Furthermore, we call S a k-Total Domination Set if every vertex in V is adjacent to at least k vertices in S. The size of the smallest Total Domination and k-Total Domination Set in a graph G is respectively called the Total Domination and k-Total Domination Number of G.Now, if there is a sequence of subsets of V like S = V0; V1; V2; : : : ; Vl = V so that for each i, every vertex in Vi is connected to at least k vertices in Vi1, S is a Dynamical k-Total... 

Renal diseases and consequently kidney failure is one of the important death factors around the world in recent years. It causes hundreds of thousands die every year and is in progress. Researchers believe that increasing chemical and nonchemical materials density in the blood which is the air pollution, use of tobacco and other parameters cause renal cells misfunction in urine filtration and regulation of blood pressure. The goal of this work is design and fabrication of a microfluidic device which provides different cell types to be cultured and imposed pressure. To do this, a high throughput microfluidic device is needed to mimic kidney biologically. Having such a device helps to analyze... 

Endothelium is the interior layer of an artery made up of tremendous number of endothelial cells which are located side by side. Finding the effective parameters that cause the cells to obtain mechanical strength in different morphologies is a major effort in cell engineering studies. In this work a numerical model for endothelial cells is developed. This model has included cell's plasma membrane (the outer membrane of the cell), nucleus and cytoskeleton main components including intermediate and actin filaments as well as microtubules. The model has been validated by simulating the adhesion of the cells to a flat substrate and also atomic force microscopy (AFM) experiments. The two most... 

The main responsibility of a primary cement job is to provide hydraulic isolation between various zones. Cement-sheath evaluation is concerned with the question of whether zonal isolation exists. Cement Evaluation Logs are used to evaluate the quality of cement sheath behind the casing or liner after cement job. these logs are a part of well integrity logs. Cement Evaluation Log results are complex and can be misunderstood, and it can lead to bad decisions that could have severe consequences. Cement evaluation logs must therefore be interpreted by experienced professionals. To help these interpreters, we propose a system for automatically interpreting cement evaluation logs, which they can... 

In this thesis, we intended to examine the noise of typical Marine Propeller. Regarding the noise source, which are due to the energy transfer to the fluid and variation of fluid force, propeller noise has been investigated in two cases. In the first case, in constant depth, the distance of hydrophone with the propeller varies. In the second case, the distance remains constant and the depth of both propeller and hydrophone has been changed, in four positions. Due to the limitation of the test tank, a pool of (5m*5m*5m), the experiments has been carried out according to the Naval Underwater Systems Center. In the second part of this research, the numerical modeling of the propeller acoustic... 

Active Learning Method (ALM) is a soft computing methodology which has been used for modeling and control. Unlike the good results of ALM’s ability, there is not any analytic expression to prove its power, because ALM’s main operators don’t satisfy fuzzy S-norm & T-norm properties. This problem considered from three viewpoints: Mathematics, Geometry and fuzzy sets. In this paper, we try to introduce two new operators based on morphology to satisfy three conditions: at first, they must be fuzzy S-norm and T-norm to confirm the committal of fuzzy set theory. Secondly, they must satisfy Demorgans law, because they are complement of each other. And finally, they resemble the main operators of... 

Tension leg platforms (TLP) are vertically moored with reserved buoyancy used for drilling and production in deep waters. Pre-tensioned tendons controls the heave, pitch and roll motions due to marine currents and waves efficiently. Seastar platforms are new generation of tension leg platforms that are similar to spar platforms that has the advantages of TLP besides spar simultaneously. This platform is usually considered as an alternative for large and cost consuming platforms. Seastar has a cylindrical surface piercing hull that creates the required buoyancy along with three submerged additional bodies. Pre-tensioned cables are attached to platform through these three submerged bodies. The... 

In this project, Fe3O4 magnetic nanoparticles were prepared by co-precipitation method. For protecting them against oxidation and also avoiding from direct contact between core and additional materials that probably makes unwanted reactions, the surface of nanoparticles were coated by SiO2 layer. Being easy to modify and having the control of interactions between nanoparticles are the advantages of coating nanoparticles with silica. The obtained Fe3O4@SiO2 core-shell nanoparticles were covered by two types of polymer (PPG and PEG). The basis of the composite was characterized by VSM, TGA, SEM, XRD, and FT-IR analytical methods.
The antibacterial activities of Copper, Silver and Gold...