Sharif Digital Repository

Irregular hemodynamics affects the progression of various vascular diseases, such atherosclerosis or aneurysms. Despite the extensive hemodynamics studies on animal models, the inter-species differences between humans and animals hamper the translation of such findings. Recent advances in vascular tissue engineering and the suitability ofin vitromodels for interim analysis have increased the use ofin vitrohuman vascular tissue models. Although the effect of flow on endothelial cell (EC) pathophysiology and EC-flow interactions have been vastly studied in two-dimensional systems, they cannot be used to understand the effect of other micro- and macro-environmental parameters associated with... 

Chondroitinase ABC I (cABC I) has received notable attention in treatment of spinal cord injuries and its application as therapeutics has been limited due to low thermal stability at physiological temperature. In this study, cABC I enzyme was immobilized on the dextran-coated Fe3O4 nanoparticles through physical adsorption to improve the thermal stability. The nanoparticles were characterized using XRD, SEM, VSM, and FTIR analyses. Response surface methodology and central composite design were employed to assess factors affecting the activity of immobilized cABC I. Experimental results showed that pH 6.3, temperature 24 °C, enzyme/support mass ratio 1.27, and incubation time 5.7 h were the... 

Energy piles have been used around the world to harvest geothermal energy to heat and cool residential and commercial buildings. In order to design energy geo-structures, thermo-mechanical response of the geothermal pile must be carefully understood. In this paper, a small scale physical model is designed and a series of heating thermal cycles with various vertical mechanical loads are performed. The instrumented pile is installed inside a dry sand bed. Changes in pile head displacement, shaft strains and pile and sand temperatures are monitored using an LVDT, strain gauges and thermocouples, respectively. Prolonged heating cycles, which would continue until boundary temperature changes,... 

Residual stresses are inherent in parts manufactured using the wire + arc additive manufacturing (WAAM) technique, resulting in unpredictable mechanical response and structural integrity (Colegrove et al.: J Mater Process Technol 213:1782-1791, 2013). An effective post-processing technique, which enhances the mechanical properties of WAAM parts, is rolling. This study investigates the vertical and pinch rolling effects on residual stress distribution in WAAM components. Initially, a WAAM model was created using a thermo-mechanical finite element modelling approach and validated against the experimental results. Subsequent to the validation of the model, the effect of the main parameters... 

This study investigates the effect of Thermal cycles on the mechanical properties of GFRP pultruded profiles with different geometries. Bending specimens consisted of I-shaped and U-channel profiles that were tested in three-point bending along their both principal weak and strong axes, whereas box profiles and laminates were used in compression and tension tests, respectively. Each specimen was exposed to a range of thermal cycles, between −20 °C and 20 °C. The failure modes of the profiles were closely investigated at both major and minor scales. Results were analyzed using ANOVA to determine the influence of each factor and a model was developed to predict the strength retention of... 

A set of complementary experiments are used for the first time to elucidate the interrelation between the mechanical properties, the strain field, and the free volume evolution during non-homogenous compression of aglassy polymer. Two sets of quenched and annealed polystyrene samples, having different free volume histories, are notched and exposed to compression. The variation of both the strain field and the free volume are measured on a microscopic scale via digital image correlation in case of strain and Doppler broadening spectroscopy of positron annihilation line in case of free volume measurements. Eventually, the interplay between the local evolution of free-volume, the local strain... 

In this paper, employing a thermomechanical small strain constitutive model for shape memory polymers (SMP), a beam element made of SMPs is presented based on the kinematic assumptions of Timoshenko beam theory. Considering the low stiffness of SMPs, the necessity for developing a Timoshenko beam element becomes more prominent. This is due to the fact that relatively thicker beams are required in the design procedure of smart structures. Furthermore, in the design and optimization process of these structures which involves a large number of simulations, we cannot rely only on the time consuming 3D finite element analyses. In order to properly validate the developed formulations, the numeric... 

Purpose: Hexagonal honeycombs with meso-metric cell size show excellent load bearing and energy absorption potential, which make them attractive in many applications. However, owing to their bend-dominated structure, honeycombs are susceptible to deformation localization. The purpose of this study is to provide insight about shear band propagation in struts of 3D-printed honeycombs and its relation to the achieved macroscopic mechanical behavior. Design/methodology/approach: Hexagonal honeycombs and unit cell models are 3D-printed by fused deposition modeling (FDM). The samples are exposed to compression loading and digital image correlation technique and finite element analyses are... 

Designing meta-materials and cellular solids with biomimetic structures has received increasing attention in the past few years partially due to advances in additive manufacturing techniques that have enabled the fabrication of advanced materials with arbitrarily complex microarchitectures and novel functionalities. To impact on this trend, it is essential to develop our understanding about the role of microstructure on mechanical responses of these structures. Although a large literature exists on the general subject, the role of microstructure on the post-yield instability is not yet adequately documented. This research introduces a numerical approach to study the post-yield instability in... 

An integrated model based on finite-element method has been proposed to examine the mechanical and thermal responses of strips and work-rolls in tandem and reverse cold rolling operations. The model has been developed such that the influence of various process parameters, such as lubrication, rolling speed, frictional state and back-up rolls, can be examined. Thermal behaviors of the rolled material and the work-rolls have been analyzed using stream-line upwind Petrov-Galerkin approach, in order to make the model applicable to high-speed rolling processes, as well. The results have been compared to the actual on-line measurements and shown to be of acceptable accuracy. Such modeling approach... 

The leaching of rare earth elements (REEs) including cerium, lanthanum and neodymium from apatite concentrate obtained from iron ore wastes by nitric acid was studied. The effects of nitric acid concentration, solid to liquid ratio and leaching time on the recoveries of Ce, La and Nd were investigated using response surface methodology. The results showed that the acid concentration and solid to liquid ratio have significant effect on the leaching recoveries while the time has a little effect. The maximum REE leaching recoveries of 66.1%, 56.8% and 51.7% for Ce, La and Nd, respectively were achieved at the optimum leaching condition with 18% nitric acid concentration, 0.06 solid to liquid... 

Crashworthiness, energy absorption capacity, and safety are important factors in the design of lightweight vehicles made of fiber-reinforced polymer composite (FRP) components. The relatively recent emergence of the nanotechnology industry has presented a novel means to augment the mechanical properties of various materials. As a result, recent attempts have contemplated the use of nanoparticles to further improve the resiliency of resins, especially when resins are used for mating FRP components. Therefore, a comprehensive understanding of the response of nanoreinforced polymer composites, subjected to various rates of loading, is of paramount importance for developing reliable structures.... 

An investigation was performed on the static strain aging behavior of warm-rolled low carbon steel during a nearly 1-year aging period, from the view point concerning with influence of changing the deformation speed and cooling media. Mechanical response of the examined material during aging period was evaluated through variations occurred in strength and hardness of the warm-deformed steel. It was shown that changing the rolling speed as well as cooling rate, may result in the occurrence of different metallurgical phenomena, consequently altering the aging kinetics of the material. It was also found that by increasing rolling speed, an increase in the value of hardness and UTS takes place,... 

Thermo-mechanical responses, developed microstructure, and mechanical properties in friction stir welding (FSW) of artificially aged AA2017 plates were investigated. A finite element analysis was first employed to evaluate hot deformation behavior of the alloy during welding. Also, hardness, yield strength, and microstructure of the welded alloy were examined using the results of the model and experimental testing. It was found that strain and temperature fields during welding are asymmetrically distributed and the maximum temperature locates in advancing side. Furthermore, considerable grain refinement is observed in the stir zone where recrystallized grains in the range of 3 to 8 m are... 

Due to environmental concerns traditional eutectic tin-lead solder is gradually being replaced in electronic assemblies by "lead-free" solders. During this transition, nanoparticle technology is also being investigated to see whether improvements in joint reliability for high temperature applications can be made. Nanoparticles can be used to harden the solder via Zener pinning of the grain boundaries and reduce fatigue failure. This paper explores the effects of adding Silica nanoparticles to SnAgCu solder, and how the mechanical properties induced in the solder vary with temperature. It is found that above 100°C the mechanical response and microstructure of the normal and nanoparticle... 

Rapid prototyping is a promising technique for producing tissue engineering scaffolds due to its capacity to generate predetermined forms and structures featuring distinct pore architectures. The objective of this study is to investigate the influences of different pore geometries and their orientation with respect to the compressive loading direction on mechanical responses of scaffolds. Plastic models of scaffolds with cubic and hexagonal unit cells were fabricated by three-dimensional (3-D) printing. An in situ imaging technique was utilized to study the progressive compressive deformation of the scaffold models. In both cubic and hexagonal geometries, organized buckling patterns relevant... 

In this paper, a novel multi-scale approach is developed for modeling of the surface effect in crystalline nano-structures. The technique is based on the Cauchy-Born hypothesis in which the strain energy density of the equivalent continua is calculated by means of inter-atomic potentials. The notion of introducing the surface effect in the finite element method is based on the intrinsic function of quadratures, called as an indicator of material behavior. The information of quadratures is derived by interpolating the data from probable representative atoms in their proximity. The technique is implemented by the definition of reference boundary CB elements, which enable to capture not only... 

In this paper, dynamic ageing characteristics associated with the application of equal channel angular pressing (ECAP) to Al6061 alloy at elevated temperatures was investigated. Followed by ECAP, Vickers microhardness measurement on the cross-sectional planes and microstructural observations were undertaken using transmission electron microscopy. The combination of the ECAP process with dynamic ageing at both 100°C and 150°C resulted in a significant increase in hardness. The grain size was measured as ∼160. nm after four passes. A comparison with the published data on the same alloy processed by ECAP at room temperature and statically aged, suggests several advantages in incorporating... 

True stress vs. true strain responses of Cu-6 wt.% Al and Cu-12 wt.% Mn alloys are presented. While Cu-6 wt.% Al alloy shows the typical mechanical response of low stacking fault energy alloys, the Cu-12 wt.% Mn alloy behaved similarly to medium to high stacking fault energy alloys. These findings clearly show that while short-range ordering triggers slip planarity, it has a minor effect on total dynamic recovery of these copper alloys  

In this paper, considering the problems of common finite element (FE) codes that consider simple constitutive equations, a developed FE code that considers a new constitutive model is used to simulate the behavior of copper sheets under severe plastic deformation (SPD). The new proposed constitutive model, that considers dislocation densities in cell interiors and cell walls of material as true internal state variables, can investigate all stages of flow stress evolution of material during large plastic deformations and also can explain the effects of strain rate magnitude on the mechanical response of material, during room temperature SPD. The proposed FE analysis is used to investigate the...