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    Cost-effective 3D H-filter fabricated by xurographic method

    , Article Microfluidics and Nanofluidics ; Volume 26, Issue 9 , 2022 ; 16134982 (ISSN) Bahari, A ; Mirzaei, A ; Taghipoor, M ; Sharif University of Technology
    Springer Science and Business Media Deutschland GmbH  2022
    Abstract
    In this paper, the conventional 2D H-filter is modified to 3D multi-layer structures fabricated by low-cost xurography. The extraction efficiency was studied experimentally for different 3D structures and then compared with conventional 2D H-filter. Numerical simulations were performed to model the diffusion flow in the proposed H-filters, showing a good agreement with the experimental observations. Results show that 3D H-filters have higher extraction efficiency at the same Reynolds number. Moreover, these structures could benefit low-cost and commercial applications due to their higher efficiency at smaller sizes. © 2022, The Author(s), under exclusive licence to Springer-Verlag GmbH... 

    Toward epileptic brain region detection based on magnetic nanoparticle patterning

    , Article Sensors (Switzerland) ; Volume 15, Issue 9 , September , 2015 , Pages 24409-24427 ; 14248220 (ISSN) Pedram, M. Z ; Shamloo, A ; Alasty, A ; Ghafar Zadeh, E ; Sharif University of Technology
    MDPI AG  2015
    Abstract
    Resection of the epilepsy foci is the best treatment for more than 15% of epileptic patients or 50% of patients who are refractory to all forms of medical treatment. Accurate mapping of the locations of epileptic neuronal networks can result in the complete resection of epileptic foci. Even though currently electroencephalography is the best technique for mapping the epileptic focus, it cannot define the boundary of epilepsy that accurately. Herein we put forward a new accurate brain mapping technique using superparamagnetic nanoparticles (SPMNs). The main hypothesis in this new approach is the creation of super-paramagnetic aggregates in the epileptic foci due to high electrical and... 

    Design and Fabrication of Brain Spinal Cord Electrodes for Rehabilitation of Rats with Spinal Cord Injuries

    , M.Sc. Thesis Sharif University of Technology Mashayekhi, Fatemeh (Author) ; Fardmanesh, Mehdi (Supervisor) ; Shanehsazzadeh, Faezeh (Co-Supervisor)
    Abstract
    The use of microelectrode arrays in neural networks has offered a wonderful opportunity for evaluating numerous properties and interactions with excitable tissues such as the brain and spinal cord in the laboratory. In neural network applications, microelectrode arrays can be utilized to analyze nerve impulses or interact with neurons. They are either used to record neural data or to stimulate spinal cord nerves. Previous research has revealed that stimulating the spinal epidural region can help restore after spinal cord injuries (SCIs), which is the key to using them in the rehabilitation of living beings, including humans. According to the international campaign for the treatment of SCI... 

    Fabrication of DEP-inertial Microfluidic Device for Focusing and Separation of Particles/Cells

    , M.Sc. Thesis Sharif University of Technology Rezaei, Mohammad Reza (Author) ; Mohammadi, Ali Asghar (Supervisor)
    Abstract
    Separation of particles and cells is one of the most important and practical methods in fields such as biomedicine, medicine and industry. In microfluidics There are various methods for particles and cells separation According to the source of them, they can be categorised as active and passive techniques. Active techniques rely on an external force field. The most important advantage of this method is controlling the force on the particles during the experiment. However, the flow speed is always limited because particles must be exposed to the outer force field for sufficient duration to achieve effective functionality. passive techniques depend entirely on the channel geometry or intrinsic... 

    Separation and Microfluidic Analysis of one Cancer Biomarker (Exosome) by Means of Microfluidic Chip Microfluidc Analysis Exosome Toward Liquid Biopsy for Cancer Tumor Cell

    , M.Sc. Thesis Sharif University of Technology Madani, Mohammad (Author) ; Saidi, Mohammad Said (Supervisor) ; Firouzabadi, Bahar (Co-Supervisor)
    Abstract
    The recent breakthroughs in the lab-on-a-chip technology will not be directly used as clinical devices unless the specific applications are carefully tested and certified. As there is a growing trend towards microfluidic devices for biomedical research, an active microfluidic device was developed. Common microfabrication methods were used to develop a microchip to separate and concentrate exosome and particular cell based on the dielectrophoresis phenomenon. Unique capabilities of the dielectrophoresis phenomenon make it a powerful tool for micro particle manipulation in micro scale. In this research, geometry for the mentioned purpose is designed and optimized. Three-dimensional... 

    Design and Fabrication of a Microfluidic Chip for Live and Dead Cell Separation

    , M.Sc. Thesis Sharif University of Technology Tajik, Parham (Author) ; Firouzbakhsh, Keykhosrow (Supervisor) ; Saeedi, Mohammad Saeed (Supervisor)
    Abstract
    The recent breakthroughs in the lab-on-a-chip technology will not be directly used as clinical devices unless the specific applications are carefully tested and certified. As there is a growing trend towards microfluidic devices for biomedical research, an active microfluidic device was developed. Common microfabrication methods were used to develop a microchip to separate and concentrate live and dead cells based on the dielectrophoresis phenomenon. Unique capabilities of the dielectrophoresis phenomenon make it a powerful tool for micro particle manipulation in micro scale. In this research, geometry for the mentioned purpose is designed and optimized. Three-dimensional microelectrodes are... 

    Fabrication of a novel six DOF thermal nanopositioner by using bulk micromachining process

    , Article IEEE International Conference on Mechatronics, ICM 2011 - Proceedings ; 2011 , pp. 702-707 ; ISBN: 9781612849836 Ghaemi, R ; Pourzand, H ; Alasty, A ; Akrami, S .M. R ; Sharif University of Technology
    Abstract
    In this paper, a novel microfabrication process of a six DOF thermal compliant nanopositioner is presented. The microfabrication process was based on bulk micromachining process. By using this process some important operational restrictions which are usually created by surface micromachining were removed. Moreover, this novel process does not need SOI wafers and needs only ordinary wafers. Therefore, it makes microfabrication process cheaper than surface micromachining processes where SOI wafer should be used. This method is completely appropriate for microactuators which have 120 degree misalignment. Finally, a primary test by using interferometer method was used to test connection of... 

    Fabrication of a novel six DOF thermal nanopositioner by using bulk micromachining process

    , Article 2011 IEEE International Conference on Mechatronics, ICM 2011 - Proceedings, 13 April 2011 through 15 April 2011 ; April , 2011 , Pages 702-707 ; 9781612849836 (ISBN) Ghaemi, R ; Pourzand, H ; Alasty, A ; Akrami, S. M. R ; Sharif University of Technology
    Abstract
    In this paper, a novel microfabrication process of a six DOF thermal compliant nanopositioner is presented. The microfabrication process was based on bulk micromachining process. By using this process some important operational restrictions which are usually created by surface micromachining were removed. Moreover, this novel process does not need SOI wafers and needs only ordinary wafers. Therefore, it makes microfabrication process cheaper than surface micromachining processes where SOI wafer should be used. This method is completely appropriate for microactuators which have 120 degree misalignment. Finally, a primary test by using interferometer method was used to test connection of...