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    Self-assembly of tryptophan-capped gold nanoparticles onto DNA network template

    , Article Journal of Dispersion Science and Technology ; Volume 30, Issue 2 , 2009 , Pages 254-258 ; 01932691 (ISSN) Sheikholeslami, Z ; Vosoughi, M ; Alemsadeh, I ; Sharif University of Technology
    2009
    Abstract
    In this study, a simple route to the formation of DNA-gold complex has been reported, using immobilized DNA as a template. The nanoporous gold films have been prepared by the electrostatic self assembly of gold nanoparticles capped with tryptophan. Tryptophan would improve surface properties of gold nanoparticles for strongly attaching to DNA. Fourier transform infrared spectroscopy confirmed that gold nanoparticles have been capped by tryptophan. Also measured zeta potential shows that there are positive charges on the surface of gold nanoparticles. Investigations by atomic force microscopy substantially confirm that tryptophan-capped gold nanoparticles can be bonded to DNA template... 

    Fabrication of metal nanowires based on self assembly of tryptophan-capped gold nanoparticle onto DNA network template

    , Article International Journal of Nanotechnology ; Volume 6, Issue 10-11 , 2009 , Pages 1041-1049 ; 14757435 (ISSN) Sheikholeslami, Z ; Vossoughi, M ; Alemzadeh, I ; Sharif University of Technology
    2009
    Abstract
    In this study, synthesis of conductive metal nanowires by using aligned and immobilised DNA strand on solid substrate is reported. The nanoporous gold film was prepared by electrostatic self assembly of gold nanoparticles capped with tryptophan. Tryptophan would improve surface properties of gold nanoparticles for strongly attaching to DNA. Fourier transform infrared (FTIR) spectroscopy confirmed that gold nanoparticles have been capped by tryptophan. Also measured zeta potential shows that there are positive charges on the surface of gold nanoparticles. Investigations by AFM observati on substantially confirm that tryptophan-capped gold nanoparticles can be bonded to DNA template... 

    Vibration control of AFM tip for nano-manipulation using combined sliding mode techniques

    , Article 2007 7th IEEE International Conference on Nanotechnology - IEEE-NANO 2007, Hong Kong, 2 August 2007 through 5 August 2007 ; 2007 , Pages 106-111 ; 1424406080 (ISBN); 9781424406081 (ISBN) Delnavaz, A ; Jalili, N ; Zohoor, H ; Sharif University of Technology
    2007
    Abstract
    Atomic force microscope (AFM) can be used as nanorobotics manipulation tool for nano particle positioning, pushing, indenting, cutting and etc. control the vibration behavior of AFM and make the micro-cantilever tip track specified trajectory is very crucial to appropriately manipulate particles in nano-scales. The novel combined sliding mode approach has been investigated in this paper to obtain robust nonlinear control scheme for nanomanipulation. First (classical) and second order (SOSM) sliding mode techniques have been developed and applied to nonlinear dynamical and uncertain model of AFM cantilever beam to track the desired trajectories. The simulation results show chattering in... 

    Dynamic & Vibration Analysis of AFM Probe Affected by the Non Uniform Potential Field

    , M.Sc. Thesis Sharif University of Technology Kahrobaiyan, Mohammad Hossein (Author) ; Ahmadian, Mohammad Taghi (Supervisor)
    Abstract
    Atomic force microscope (AFM) has a significant capability of imaging surface topography on an atomic scale. It is also widely used for Nanolithography in MEMS/NEMS (micro/nanoelectromechanical systems). Conventional AFMs consist of a cantilever with a sharp conical or pyramidal tip located at the free end of the cantilever that plays an important role in AFM measurements. Scanning across a surface, AFM interacts with the sample surface through its tip. Although the dynamic behavior of the AFM cantilever is complicated, the researchers have been interested in studying AFM dynamic behavior because it has a great influence on the surface imaging process. The imaging rate and contrast of... 

    Using Surface Properties of Immiscible Fluids in Capillary Tubes for Identification and Separation of Cancerous Blood Cells

    , M.Sc. Thesis Sharif University of Technology Alinejad, Amin (Author) ; Ayatollahi, Shahabodin (Supervisor) ; Vossoughi, Manochehr (Supervisor)
    Abstract
    Cancer has been known as one of the main reasons for disease-related deaths in the last decades. Early diagnosis could significantly reduce the level of fatality chances. Among the known cancer types, lung cancer is one of the most malignant ones. The common diagnosticmethods are expensive and using high-technology methods; therefore, the introduction of simple and cheap methods is very urgent to detect it. In this project, surface and interfacial tension measurement of cancerous and normal lung cells have been investigated as an easy detection technique. Among the common measurement methods, Pendant Drop and Capillary height techniques have been utilized in this research work. The obtained... 

    Feasibility Study of Deposition by SUT-PF

    , M.Sc. Thesis Sharif University of Technology Safarzadehamiri, Ali (Author) ; Vosoughi, Naser (Supervisor)
    Abstract
    Sharif University of Technology Plasma Focus (SUT-PF) is a Mather Type DPF device which has a 39 μF capacitor bank with 14 KV charging ability at its ultimate limit corresponding to 7 KJ stored energy. In the first step of this experiment, a test has been done at three distances 5, 7, 10 cm from anode tip with the different number of shots 20, 30, and 40 at 0 constant angles.In the following, a test is done at 5 and 10 degrees with 40 shots, and PF chamber has been filled up with nitrogen gas. Various tests have carried out for survey of this experiment, the result of which are as follow:The X-ray diffraction (XRD) analysis are used in order to reveal if the Nickel or Nickel nitride have... 

    Simulation of a Simple Model of Endothelial Cell Using Dissipative Particle Dynamics Method

    , M.Sc. Thesis Sharif University of Technology Kiyoumarsi Oskouei, Amir (Author) ; Saeedi, Mohammad Saeed (Supervisor) ; Firoozabadi, Bahar (Co-Advisor)
    Abstract
    Endothelium is the interior layer of an artery made up of tremendous number of endothelial cells which are located side by side. Finding the effective parameters that cause the cells to obtain mechanical strength in different morphologies is a major effort in cell engineering studies. In this work a numerical model for endothelial cells is developed. This model has included cell's plasma membrane (the outer membrane of the cell), nucleus and cytoskeleton main components including intermediate and actin filaments as well as microtubules. The model has been validated by simulating the adhesion of the cells to a flat substrate and also atomic force microscopy (AFM) experiments. The two most... 

    Design and Fabrication of Tip for a Nanolithography System

    , M.Sc. Thesis Sharif University of Technology Tayefeh Younesi, Ali (Author) ; Rashidian, Bijan (Supervisor)
    Abstract
    Various applications of nanostructures in electronics, optoelectronics, MEMS, photonics and plasmonic make their fabrication an interesting research topic recently. Progress in nanotechnology depends on the capability to fabricate, position and interconnect nanometer-scale structures. The development of fabrication devices with nanoscales is mainly dependent on the existence of a suitable nanolithography approach. Patterning materials with nanoscale features aimed at improving integration and device performance faced several challenges. The limitation of conventional lithography systems including resolution related issues, operational costs and lack of flexibility to pattern organic and... 

    Manipulation of biomolecules: A molecular dynamics study

    , Article Current Applied Physics ; Volume 14, Issue 9 , September , 2014 , Pages 1216-1227 ; ISSN: 15671739 Mahdjour Firouzi, M. A ; Nejat Pishkenari, H ; Mahboobi, S. H ; Meghdari, A ; Sharif University of Technology
    Abstract
    With the rapid progression of bionanorobotics, manipulation of nano-scale biosamples is becoming increasingly attractive for different biological purposes. Nevertheless, the interaction between a robotic probe and a biological sample is poorly understood and the conditions for appropriate handling is not well-known. Here, we use the molecular dynamics (MD) simulation method to investigate the manipulation process when a nanoprobe tries to move a biosample on a substrate. For this purpose, we have used Ubiquitin (UBQ) as the biomolecule, a single-walled carbon nanotube (SWCNT) as the manipulation probe, and a double-layered graphene sheets as the substrate. A series of simulations were... 

    Electronic structure and morphological study of BaTiO 3 film grown by pulsed-laser deposition

    , Article Materials Letters ; Volume 72 , April , 2012 , Pages 107-109 ; 0167577X (ISSN) Ahadi, K ; Mahdavi, S. M ; Nemati, A ; Tabesh, M ; Ranjbar, M ; Sharif University of Technology
    Abstract
    The morphological characteristics and electronic structure of the BaTiO 3 films grown by pulsed-laser deposition technique have been investigated. AFM and FE-SEM images reveal columnar growth characteristic of these films. Utilizing spectrophotometer, optical band gap of the films were reckoned to be about 3.76 eV. Both dα/dE and PL vs. E plots reveal numerous luminance states in the gap. Despite the presence of many luminance faults in the gap, cations manage to preserve their electronic states  

    Resonant frequency and sensitivity of an AFM microcantilever modeled by the non-local theory

    , Article ASME 2011 International Mechanical Engineering Congress and Exposition, IMECE 2011, 11 November 2011 through 17 November 2011 ; Volume 11 , November , 2011 , Pages 239-245 ; 9780791854976 (ISBN) Khosravani, E ; Kahrobaiyan, M. H ; Ahmadian, M. T ; Sharif University of Technology
    Abstract
    In this paper, utilizing the non-local theory, the resonant frequency and sensitivity of an AFM microcantilever are investigated. To that end, the governing equation of motion and corresponding boundary conditions are obtained using the variational approach. Afterwards, the resonant frequency and sensitivity of the AFM microcantilever are derived analytically and depicted in some figures versus the contact stiffness of the sampling surface. The results of the current model are compared to those of the classical theory. The comparison shows that the difference between the results of the non-local theory and those of the classical theory is significant when the non-local parameter is high but... 

    Tip and sample flexibility effects on tapping mode (amplitude modulation) AFM measurements

    , Article Micro and Nano Letters ; Volume 6, Issue 12 , December , 2011 , Pages 1023-1028 ; 17500443 (ISSN) Pishkenari, H. N ; Meghdari, A ; Sharif University of Technology
    2011
    Abstract
    This Letter is devoted to the investigation of the tip, substrate and particle flexibility effects on the elastic deformation, the maximum repulsive force and the topography images in tapping mode (amplitude modulation) atomic force microscopy (TM-AFM). Several quantitative comparisons among the different models are presented and the effects of the elastic deformations on TM-AFM measurement are investigated  

    Simulation of imaging in tapping-mode atomic-force microscopy: A comparison amongst a variety of approaches

    , Article Journal of Physics D: Applied Physics ; Volume 44, Issue 7 , February , 2011 ; 00223727 (ISSN) Pishkenari, H. N ; Mahboobi, S. H ; Meghdari, A ; Sharif University of Technology
    2011
    Abstract
    Models capable of accurate simulation of microcantilever dynamics coupled with complex tip-sample interactions are essential for interpretation and prediction of the imaging results in amplitude modulation or tapping-mode atomic-force microscopy (AM-AFM or TM-AFM). In this paper, four approaches based on combinations of lumped and finite element methods for modelling of cantilever dynamics, and van derWaals and molecular dynamics for modelling of tip-sample interactions, are used to simulate the precise imaging by AM-AFM. Based on the simulated imaging and force determination, the efficiency of different modelling schemes is evaluated. This comparison is performed considering their... 

    Study of Biomolecules Imaging Using Molecular Dynamics Simulations

    , Article Nano ; Volume 10, Issue 7 , October , 2015 ; 17932920 (ISSN) Kheirodin, M ; Nejat Pishkenari, H ; Moosavi, A ; Meghdari, A ; Sharif University of Technology
    World Scientific Publishing Co. Pte Ltd  2015
    Abstract
    The process of imaging a biomolecule by atomic force microscope (AFM) is modeled using molecular dynamics (MD) simulations. Since the large normal force exerted by the tip on the biosample in contact and tapping modes may damage the sample structure and produce irreversible deformation, the noncontact mode of AFM (NC-AFM) is employed as the operating mode. The biosample is scanned using a carbon nanotube (CNT) as the AFM probe. CNTs because of their small diameter, high aspect ratio and high mechanical resistance attract many attentions for imaging purposes. The tip-sample interaction is simulated by the MD method. The protein, which has been considered as the biomolecule, is ubiquitin and a... 

    Torsional sensitivity and resonant frequency of an AFM with parallel sidewall probes

    , Article Proceedings of the ASME Design Engineering Technical Conference, 15 August 2010 through 18 August 2010, Montreal, QC ; Volume 5 , 2010 , Pages 987-996 ; 9780791844137 (ISBN) Ahmadian, M. T ; Kahrobaiyan, M. H ; Haghighi, P ; Yousefi, A ; Sharif University of Technology
    2010
    Abstract
    The resonant frequencies and torsional sensitivities of an atomic force microscope (AFM) assembled cantilever probe which comprises a horizontal cantilever, two vertical extensions and two tips located at their free ends are studied. This probe makes the AFM capable of measuring, for instance, the outer/inner diameter, roundness and roughness of microstructures like micro-holes and micro nozzles which leads to a time-saving swift scanning process. In this work, the effects of the sample surface contact stiffness and the geometrical parameters such as the ratio of the vertical extension length to the horizontal cantilever length and the distance of the first vertical extension from the... 

    An investigation on the torsional sensitivity and resonant frequency of an AFM with sidewall and top-surface probes

    , Article ASME 2010 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference, IDETC/CIE2010, Montreal, QC, 15 August 2010 through 18 August 2010 ; Volume 4 , 2010 , Pages 589-599 ; 9780791844120 (ISBN) Kahrobaiyan, M. H ; Ahmadian, M. T ; Haghighi, P ; Haghighi, A ; Sharif University of Technology
    2010
    Abstract
    The resonant frequencies and torsional sensitivities of an atomic force microscope (AFM) with assembled cantilever probe (ACP) are studied. This ACP comprises a horizontal cantilever, a vertical extension and two tips located at the free ends of the cantilever and the extension which makes the AFM capable of simultaneous topography at top-surface and sidewalls of microstructures especially microgears which consequently leads to a time-saving swift scanning process. In this work, the effects of the sample surface contact stiffness and the geometrical parameters such as the ratio of the vertical extension length to the horizontal cantilever length and the distance of the vertical extension... 

    An investigation on the flexural sensitivity and resonant frequency of an AFM with sidewall and top-surface probes

    , Article ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE), 12 November 2010 through 18 November 2010, Vancouver, BC ; Volume 10 , 2010 , Pages 419-427 ; 9780791844472 (ISBN) Kahrobaiyan, M. H ; Ahmadian, M. T ; Haghighi, P ; Haghighi, A ; Sharif University of Technology
    2010
    Abstract
    The resonant frequencies and flexural sensitivities of an atomic force microscope (AFM) assembled cantilever probe which comprises a horizontal cantilever, a vertical extension and two tips located at the free ends of the cantilever and the extension are studied. This probe makes the AFM capable of simultaneous topography at top-surface and sidewalls of microstructures especially microgears which leads to a time-saving swift scanning process. In this work, the effects of the sample surface contact stiffness and the geometrical parameters such as the ratio of the vertical extension length to the horizontal cantilever length and the distance of the vertical extension from clamped end of the... 

    Torsional sensitivity of the first four modes of an AFM cantilever with a sidewall probe using analytical method

    , Article Proceedings of the ASME International Design Engineering Technical Conferences and Computers and Information in Engineering Conference 2009, DETC2009, 30 August 2009 through 2 September 2009, San Diego, CA ; Volume 6 , August-September , 2010 , Pages 617-622 ; 9780791849033 (ISBN) Kahrobaiyan, M. H ; Rahaeifard, M ; Ahmadian, M. T ; Sharif University of Technology
    2010
    Abstract
    In this study, using analytical method, the torsional resonant frequency and torsional sensitivity of the first four modes of an AFM cantilever with sidewall probe including a horizontal cantilever and a vertical extension is analyzed and a closed form for torsional sensitivity of the probe is derived. In addition, the effect of relative parameters such as ratio of vertical extension length to horizontal cantilever length is investigated. According to this study, the results show that as contact stiffness increases, the resonant frequencies of all vibration modes increases until they reach constant values at very high values of contact stiffness. It is also can be found that low-order modes... 

    Analytical and experimental frequency response analysis of microcantilevers subject to tip-sample interaction

    , Article Proceedings of the ASME International Design Engineering Technical Conferences and Computers and Information in Engineering Conference 2009, DETC2009, 30 August 2009 through 2 September 2009 ; Volume 6 , September , 2010 , Pages 575-581 ; 9780791849033 (ISBN) Delnavaz, A ; Mahmoodi, S. N ; Jalili, N ; Zohoor, H ; Sharif University of Technology
    Abstract
    Improvement of microcantilever-based sensors and actuators chiefly depends on how comprehensively they are modeled and precisely formulated. Atomic Force Microscopy (AFM) is the most widespread application of microcantilever beam as a sensor, which is usually influenced by the tip-sample interaction force. For this, vibration of AFM microcantilever probe is analyzed in this paper, along with analytical, numerical and experimental investigation of the influence of the sample interaction force on the microcantilever vibration. Nonlinear integro-partial equation of microcantilever vibration subject to the tip-sample interaction is then derived and numerically simulated. Moreover, multiple time... 

    Torsional sensitivity of the first four modes of an AFM cantilever with a sidewall probe using analytical method

    , Article Proceedings of the ASME International Design Engineering Technical Conferences and Computers and Information in Engineering Conference 2009, DETC2009 ; Volume 6 , 2009 , Pages 617-622 ; 9780791849033 (ISBN) Kahrobaiyan, M. H ; Rahaeifard, M ; Ahmadian, M. T ; Sharif University of Technology
    Abstract
    In this study, using analytical method, the torsional resonant frequency and torsional sensitivity of the first four modes of an AFM cantilever with sidewall probe including a horizontal cantilever and a vertical extension is analyzed and a closed form for torsional sensitivity of the probe is derived. In addition, the effect of relative parameters such as ratio of vertical extension length to horizontal cantilever length is investigated. According to this study, the results show that as contact stiffness increases, the resonant frequencies of all vibration modes increases until they reach constant values at very high values of contact stiffness. It is also can be found that low-order modes...