Sharif Digital Repository

In this study, antibacterial activity, biocompatibility, and corrosion resistance of 316 LVM implants were improved using the development of HAp/GO/Ag nanocomposite coatings by the dip-coating method. The XRD and FTIR results confirmed the synthesis of HAp/GO/Ag nanocomposites. HAp/Ag nanoparticles (68 nm) bound to epoxy, hydroxyl, and carboxyl functional groups on GO sheets (size of GO sheets varies from 255 to 1480 nm) by electrostatic interaction. FESEM images showed that HAp/GO/Ag coatings had higher density and fewer micro-cracks than pure HAp coatings. In addition, HAp/GO/Ag coatings showed optimized nano-hardness (4.5 GPa) and elasticity modulus (123 GPa). The results of... 

In this study, optimized preparation, quality control, cell assessments and biostribution of 188Re-HYNIC-PSMA in normal rats and tumor bearing mice are studied. Optimized conditions for radiolabeling were evaluated and radiochemical purity (> 99%) was investigated using ITLC and HPLC methods. 188Re-HYNIC-PSMA was stable both in PBS (4 °C) and in human serum (37 °C) even after 48 h. The results showed the complex was cleared from the blood very fast via urinary track. This new radiolabeled compound has a high potential to be considered as an agent for the treatment of patients with PSMA expressing tumors however more biological studies are still needed. © 2022, Akadémiai Kiadó, Budapest,... 

The failure of mechanical components is a common phenomenon in satellites. This failure can happen in the satellite attitude control system, which causes that the control system of the satellite becomes underactuated. There have been many attempts to control the orientation of underactuated satellites. However, in most studies, the inertia matrix of the satellite is assumed to be diagonal with respect to the body coordinate system, and no limitations on the amount of torque applied by the reaction wheels have been considered. In this paper, at first, it is attempted to control the satellite using the motion planning method. The satellite control inputs are assumed to be cubic spline with... 

This study aims to investigate the nonlinear dynamic characteristics of annular cylinders coupled with a fluid medium to identify the effective parameters on stability margins at different rotation speeds. To achieve this, stability and nonlinear vibrations of rotating cylindrical shells containing incompressible annular fluid are considered. The fluid medium is bounded by a rigid external cylinder. Sanders–Koiter kinematic assumptions are utilized to determine the geometrically nonlinear structural equations of motion. These equations are then used to investigate finite amplitude vibrations of various fluid-loaded shells at different states. A penalty approach is introduced by using... 

A modified unscented Kalman filter is presented to estimate the quaternion parameters as well as the angular velocities of a rigid gyro-less satellite under faulty sensor conditions. The task is carried out using the Sun sensor and magnetometers as attitude sensors with bounded noise and unknown fault(s). Following the presentation of the satellite attitude dynamics and filtering formulations, a new fault detection and isolation algorithm is proposed. The latter is based on a modified unscented Kalman filter structure for improved fault detection, sensor isolation, and attitude control (AC). A Backtracking Search Algorithm (BSA) is also used to design and optimize the PID controller gains,... 

In this paper, the drivetrain identification problem of a horizontal axis gear-driven wind turbine has been considered. The identification problem leads to a precise model of the drivetrain of the wind turbines which plays a key role in the production and transmission of electrical energy. This process consists of two stages: First, offline identification which needs the input–output data from the drivetrain system. These data are obtained from the FAST code. FAST (Fatigue, Aerodynamics, Structures, and Turbulence) is a valid aeroelastic code in the simulation aeroelastic field of offshore and onshore wind turbines. In region 2 (wind velocity is between the cut-in and rated velocities), the... 

Magnesium and its alloys have gained significant popularity due to their light weight and their potential for use as bioresorbable materials. However, their application is limited in practice due to their relatively poor corrosion resistance. Several methods are available for improving the corrosion resistance of Mg alloys for bio-applications such as using different coatings, alloying, and modifying the microstructural parameters such as the grain size and the crystallographic texture. This review provides a comprehensive summary of the effects of crystallographic texture and twinning, as one of the most important deformation mechanisms of Mg and Mg alloys, on the corrosion behavior.... 

Natural disasters threaten the sustainability of electric power supply. This fact highlights the importance of enhancing technological resourcefulness to handle the upcoming events. Once a natural disaster occurs, the most urgent undertaking is to rapidly pinpoint and assess component damages and dispatch the repair crews towards the most critical impaired elements. Practical efforts confirm that utilising a drone, which is an unmanned aerial vehicle, can notably reduce the duration of post-disaster distribution system damage assessment (DA) and increase the resilience of power systems. This study presents an optimisation model to determine the optimal number and type of drones required for... 

Multispeed resolvers are used in the applications that need higher accuracy. However, they suffer from losing absolute position information. To overcome this challenge and improve the reliability of detecting position, the use of multiturn resolvers is recommended. The conventional configuration of multiturn resolver is using two individual resolvers on one shaft and into a common frame. Using such configuration needs special care on setting the distance between two resolvers. In this article, a new structure based on a dual side configuration is proposed. The performance of the double-sided resolver is analyzed and optimized using an analytical model based on a magnetic equivalent circuit.... 

In the contemporary sustainable urban set up, one of the critical issues adversely affecting the quality of life in urban areas and inflicting immense costs on cities is traffic congestion. Traffic congestion is an outgrowth of increased traffic flow in certain locations of large cities. Recently, urban decision-makers and transportation planners resort to one-way traffic system as an effective traffic management strategy, which has a profound effect on reducing traffic congestion and improving traffic flow, leading to urban sustainability. In the present paper, the authors endeavored to develop a novel methodological framework based on optimization techniques in order to mitigate traffic... 

In this study, spinel CuCo2O4 (CCO) with a hierarchical hollow sphere morphology was encapsulated in V2O5-decorated ultra-wrinkled graphitic carbon-nitride (VO-UCN) for the first time via a facile glycerol-assisted solvothermal method in the interest of developing a novel high-efficiency double Z-type nano-photocatalyst (denoted as VO-UCN@CCO). The remarkable physicochemical features of the as-prepared nano-photocatalysts were verified using diverse characterization techniques including TGA, XRD, FT-IR, FE-SEM, TEM, BET, UV–vis DRS, PL, EIS, and transient photocurrent techniques. Herein, VO-UCN@CCO nanocomposite was employed for the photodisintegration of levofloxacin (LVOF) antibiotic under... 

Targeted drug delivery systems using nanocarriers offer a versatile platform for breast cancer treatment; however, a robust, CD44-targeted niosomal formulation has not been developed and deeply studied (both in vitro and in vivo) yet. Here, an optimized system of epirubicin (Epi)-loaded niosomal nanoparticles (Nio) coated with hyaluronic acid (HA) has been engineered for targeting breast cancer cells. The nanoformulation was first optimized (based on size, polydispersity index, and entrapment efficiency); then, we characterized the morphology, stability, and release behavior of the nanoparticles. Epirubicin release from the HA-coated system (Epi-Nio-HA) showed a 21% (acidic buffer) and 20%... 

Renewable energy (RE) as a new player in the generation sector of power systems imposes new challenges to the system operators. The intermittent nature of REs for systems where are autonomous calls for new operational and planning strategies to reach more efficient power management. An autonomous hybrid green power system (HGPS) should be able to meet the load while keeping the cost of the HGPS as low as possible. Many studies have presented different un-optimal and optimal operational strategies, a few of which were optimally sized. In this regard, this paper develops a new thorough framework for designing and optimizing an autonomous HGPS. To reach this goal, the proposed model (a)... 

Higher than a standard level, the humidity provides a suitable environment for the pathogenic microorganisms to grow and increases energy consumption for cooling, increasing greenhouse gas emissions. Desiccant air-conditioning (DAC) is an effective method to reduce humidity and energy simultaneously. Conventional desiccants are not suitable for use as a desiccant in building air conditioners, mainly because of high regeneration temperature and other issues such as limited equilibrium capacity and hydrothermal and cyclic instability. Metal-organic frameworks (MOFs) are a novel class of porous crystalline materials without the disadvantages of traditional desiccants. They benefit from a huge... 

Body posture measurement approaches, required in biomechanical models to assess risk of musculoskeletal injuries, are usually costly and/or impractical for use in real workplaces. Therefore, we recently developed three artificial neural networks (ANNs), based on measured posture data on several individuals, to predict whole body 3D posture (coordinates of 15 markers located on body's main joints), segmental orientations (Euler angles of 14 body segments), and lumbosacral (L5-S1) moments during static manual material handling (MMH) activities (ANNPosture, ANNAngle, and ANNMoment, respectively). These ANNs require worker's body height, body weight (only for ANNMoment), hand-load 3D position,... 

This letter presents a unified framework for the design of prescribed-time controllers under time-varying input and state constraints for normal-form unknown nonlinear systems with uncertain input gain. The proposed approach is based on a time-domain mapping method by which any infinite-time system can be corresponded to a prescribed-time system and vice versa. It is shown that the design of a constrained nonasymptotic prescribed-time controller can be reduced to the asymptotic control design for an associated constrained infinite-time system. Faà di Bruno's formula and Bell polynomials are used for a constructive representation of the associated infinite-time system. The presented results... 

Herein, an efficient and sustainable one-pot, four-component access to rhodanine-oxindole derivatives is achieved by a reaction between primary amines, carbon disulfide, ethyl chloroacetate, and cyano-substituted alkenyl oxindoles. The reaction was conducted without any harsh conditions as well as exhausting workup in polyethylene glycol (PEG) as a green solvent at room temperature and delivered rhodanine-oxindole products in high yield. This publication is the first easy protocol to be reported for the rapid construction of new rhodanine-oxindole derivatives at room temperature without harsh conditions and via multicomponent reaction. © 2021 Taylor & Francis Group, LLC  

Breast cancer is one of the most prevalent causes of cancer mortality in women. In order to increase patient prognosis and survival rates, new technologies are urgently required to deliver therapeutics in a more effective and efficient manner. Niosome nanoparticles have been recently employed as therapeutic platforms capable of loading and carrying drugs within their core for both mono and combination therapy. Here, niosome-based nanoscale carriers were investigated as a targeted delivery system for breast cancer therapy. The platform developed consists of niosomes loaded with letrozole and cyclophosphamide (NLC) and surface-functionalized with a folic-acidtargeting moiety (NLCPFA). Drug...