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    Ruthenium/Ruthenium oxide hybrid nanoparticles anchored on hollow spherical Copper-Cobalt Nitride/Nitrogen doped carbon nanostructures to promote alkaline water splitting: Boosting catalytic performance via synergy between morphology engineering, electron transfer tuning and electronic behavior modulation

    , Article Journal of Colloid and Interface Science ; Volume 626 , 2022 , Pages 1070-1084 ; 00219797 (ISSN) Rezaee, S ; Shahrokhian, S ; Sharif University of Technology
    Academic Press Inc  2022
    Abstract
    Exploring bi-functional electrocatalysts with excellent activity, good durability, and cost-effectiveness for electrochemical hydrogen and oxygen evolution reactions (HER and OER) in the same electrolyte is a critical step towards a sustainable hydrogen economy. Three main features such as high density of active sites, improved charge transfer, and optimized electronic configuration have positive effects on the electrocatalyst activity. In this context, understanding structure–composition–property relationships and catalyst activity is very important and highly desirable. Herein, for the first time, we present the design and fabrication of novel MOF-derived ultra-small Ru/RuO2 nanoparticles... 

    Bioinspired nanofiber scaffold for differentiating bone marrow-derived neural stem cells to oligodendrocyte-like cells: Design, fabrication, and characterization

    , Article International Journal of Nanomedicine ; Volume 15 , 2020 , Pages 3903-3920 Boroojeni, F. R ; Mashayekhan, S ; Abbaszadeh, H. A ; Ansarizadeh, M ; Khoramgah, M. S ; Rahimi Movaghar, V ; Sharif University of Technology
    Dove Medical Press Ltd  2020
    Abstract
    Background: Researchers are trying to study the mechanism of neural stem cells (NSCs) differentiation to oligodendrocyte-like cells (OLCs) as well as to enhance the selective differentiation of NSCs to oligodendrocytes. However, the limitation in nerve tissue acces-sibility to isolate the NSCs as well as their differentiation toward oligodendrocytes is still challenging. Purpose: In the present study, a hybrid polycaprolactone (PCL)-gelatin nanofiber scaffold mimicking the native extracellular matrix and axon morphology to direct the differentiation of bone marrow-derived NSCs to OLCs was introduced. Materials and Methods: In order to achieve a sustained release of T3, this factor was... 

    Graphene-based nanomaterials in fighting the most challenging viruses and immunogenic disorders

    , Article ACS Biomaterials Science and Engineering ; Volume 8, Issue 1 , 2022 , Pages 54-81 ; 23739878 (ISSN) Ebrahimi, M ; Asadi, M ; Akhavan, O ; Sharif University of Technology
    American Chemical Society  2022
    Abstract
    Viral diseases have long been among the biggest challenges for healthcare systems around the world. The recent Coronavirus Disease 2019 (COVID-19) pandemic is an example of how complicated the situation can get if we are not prepared to combat a viral outbreak in time, which brings up the need for quick and affordable biosensing platforms and vast knowledge of potential antiviral effects and drug/gene delivery opportunities. The same challenges have also existed for nonviral immunogenic disorders. Nanomedicine is considered a novel candidate for effectively overcoming these worldwide challenges. Among the versatile nanomaterials commonly used in biomedical applications, graphene has recently...