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    A Multilayer Approach to Network Immunization Based on Digital Information

    , M.Sc. Thesis Sharif University of Technology Joneydi, Sara (Author) ; Khansari, Mohammad (Supervisor)
    Abstract
    Researching in the field of optimization of network immunizing and epidemic spreading is an active and important area. According to literature review, influential nodes are detected based on global graph metrics such as centrality measures. On the other hand, when a network infrastructure is not available and a direct or straight path between source and destination may not be accessible, one can use opportunistic networks routing protocols in Delay Tolerant Networks to recognize influential users is an appropriate approach. In this work, we use a real world three layer dataset which consists of digital data (social relations and Bluetooth contact traces) of individuals. We convert the real... 

    Study of Antibacterial Performance of Metal Oxide Nanostructures and their Effect on Bacterial Growth Kinetics

    , M.Sc. Thesis Sharif University of Technology Afkhami, Fatemeh Sadat (Author) ; Naseri, Naimeh (Supervisor) ; Zaker Moshfegh, Alireza (Co-Supervisor)
    Abstract
    Fighting contagious microbial diseases is considered a serious health issue, which has attracted much attention in worldwide. Thus, development of new materials based on nanostructures as a new generation of antibiotics to address this challenge has been of interest to researchers in recent years. Nanostructures based on metallic oxide semiconductors such as oxides with light absorption, production of electron-hole pairs in needle like structures cause tearing bacterial membrane and eventually destroy the bacterium. To this end, we designed experiments to study mechanism and physics governing the process of bacterial degradation to determine the best conditions for inhibiting bacteria... 

    A Systems Dynamics Approach to Simulate Epidemic Spread of Covid-19

    , M.Sc. Thesis Sharif University of Technology Sepehri, Sepehr (Author) ; Roosta Azad, Reza (Supervisor)
    Abstract
    The outbreak of a type of corona virus in 2019, plunged the world into a huge panic. Businesses entered into an unprecedented recession and economic growth was severely reduced. Millions of people have been infected and unfortunately countless numbers have also lost their lives. This which quickly crossed the borders of countries, proved how much a not-so-deadly infectious disease can affect human life. Another point that was revealed was the importance of epidemiology knowledge. Since the beginning of the outbreak of this disease, scientists in this field have tried to predict the state of the disease in the coming days by presenting models. Many countries formed special working groups to... 

    Identifying the Effect of Gasoline Consumption on Pollutant Emissions with the help of The Covid-19 Outbreak Exogenous Shock

    , M.Sc. Thesis Sharif University of Technology Abouzarpoor, Hassan (Author) ; Rahmati, Mohammad Hossein (Supervisor)
    Abstract
    Gasoline consumption resulting from vehicular traffic is one of the most significant factors influencing the emission levels of pollutants. Since the sold gasoline at fuel stations does not necessarily translate into vehicular traffic, tracing the final consumer becomes challenging. hence, estimating the impact of gasoline consumption on air pollution is accompanied by biased results. Moreover, the COVID-19 outbreak, acting as an exogenous shock, has provided an opportunity to use data such as COVID-19 and intercity travel as instrumental variables, gasoline consumption, and emission levels, between 2018 and 2020, show unbiased estimates of the effect of gasoline consumption on air... 

    Nonlinear robust adaptive sliding mode control of influenza epidemic in the presence of uncertainty

    , Article Journal of Process Control ; Volume 56 , 2017 , Pages 48-57 ; 09591524 (ISSN) Sharifi, M ; Moradi, H ; Sharif University of Technology
    Elsevier Ltd  2017
    Abstract
    In this paper, a nonlinear robust adaptive sliding mode control strategy is presented for the influenza epidemics in the presence of model uncertainties. The nonlinear epidemiological model of influenza with five state variables (the numbers of susceptible, exposed, infected, asymptomatic and recovered individuals) and two control inputs (vaccination and antiviral treatment) is considered. The objective of the proposed controller is decreasing the number of susceptible and infected humans to zero by tracking the desired scenarios. As a result of this decreasing, the number of exposed and asymptomatic individuals is also decreased and converged to the zero. Accordingly, it is shown that the... 

    A dynamic incentive mechanism for security in networks of interdependent agents

    , Article 7th EAI International Conference on Game Theory for Networks, GameNets 2017, 9 May 2017 through 9 May 2017 ; Volume 212 , 2017 , Pages 86-96 ; 18678211 (ISSN); 9783319675398 (ISBN) Farhadi, F ; Tavafoghi, H ; Teneketzis, D ; Golestani, J ; Sharif University of Technology
    Springer Verlag  2017
    Abstract
    We study a dynamic mechanism design problem for a network of interdependent strategic agents with coupled dynamics. In contrast to the existing results for static settings, we present a dynamic mechanism that is incentive compatible, individually rational, budget balanced, and social welfare maximizing. We utilize the correlation among agents’ states over time, and determine a set of inference signals for all agents that enable us to design a set of incentive payments that internalize the effect of each agent on the overall network dynamic status, and thus, align each agent’s objective with the social objective. © 2017, ICST Institute for Computer Sciences, Social Informatics and... 

    Performance evaluation of epidemic content retrieval in DTNs with restricted mobility

    , Article IEEE Transactions on Network and Service Management ; Volume 16, Issue 2 , 2019 , Pages 701-714 ; 19324537 (ISSN) Rashidi, L ; Entezari Maleki, R ; Chatzopoulos, D ; Hui, P ; Trivedi, K. S ; Movaghar, A ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2019
    Abstract
    In some applicable scenarios, such as community patrolling, mobile nodes are restricted to move only in their own communities. Exploiting the meetings of the nodes within the same community and the nodes within the neighboring communities, a delay tolerant network (DTN) can provide communication between any two nodes. In this paper, two analytical models based on stochastic reward nets (SRNs) are proposed to evaluate the performance of the epidemic content retrieval in such multi-community DTNs. Performance measures computed by the proposed models are the average retrieval delay and the average number of transmissions. The monolithic SRN model proposed in the first step is not scalable, in... 

    Centrality-based epidemic control in complex social networks

    , Article Social Network Analysis and Mining ; Volume 10, Issue 1 , 2020 Doostmohammadian, M ; Rabiee, H. R ; Khan, U. A ; Sharif University of Technology
    Springer  2020
    Abstract
    Recent progress in the areas of network science and control has shown a significant promise in understanding and analyzing epidemic processes. A well-known model to study epidemics processes used by both control and epidemiological research communities is the susceptible–infected–susceptible (SIS) dynamics to model the spread of disease/viruses over contact networks of infected and susceptible individuals. The SIS model has two metastable equilibria: one is called the endemic equilibrium and the other is known as the disease-free or healthy-state equilibrium. Control theory provides the tools to design control actions (allocating curing or vaccination resources) in order to achieve and... 

    Modeling epidemic routing: capturing frequently visited locations while preserving scalability

    , Article IEEE Transactions on Vehicular Technology ; Volume 70, Issue 3 , 2021 , Pages 2713-2727 ; 00189545 (ISSN) Rashidi, L ; Dalili Yazdi, A ; Entezari Maleki, R ; Sousa, L ; Movaghar, A ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2021
    Abstract
    This paper investigates the performance of epidemic routing in mobile social networks considering several communities which are frequently visited by nodes. To this end, a monolithic Stochastic Reward Net (SRN) is proposed to evaluate the delivery delay and the average number of transmissions under epidemic routing by considering skewed location visiting preferences. This model is not scalable enough, in terms of the number of nodes and frequently visited locations. In order to achieve higher scalability, the folding technique is applied to the monolithic model, and an approximate folded SRN is proposed to evaluate performance of epidemic routing. Discrete-event simulation is used to... 

    A review on computer-aided chemogenomics and drug repositioning for rational COVID-19 drug discovery

    , Article Chemical Biology and Drug Design ; Volume 100, Issue 5 , 2022 , Pages 699-721 ; 17470277 (ISSN) Maghsoudi, S ; Taghavi Shahraki, B ; Rameh, F ; Nazarabi, M ; Fatahi, Y ; Akhavan, O ; Rabiee, M ; Mostafavi, E ; Lima, E. C ; Saeb, M. R ; Rabiee, N ; Sharif University of Technology
    John Wiley and Sons Inc  2022
    Abstract
    Application of materials capable of energy harvesting to increase the efficiency and environmental adaptability is sometimes reflected in the ability of discovery of some traces in an environment―either experimentally or computationally―to enlarge practical application window. The emergence of computational methods, particularly computer-aided drug discovery (CADD), provides ample opportunities for the rapid discovery and development of unprecedented drugs. The expensive and time-consuming process of traditional drug discovery is no longer feasible, for nowadays the identification of potential drug candidates is much easier for therapeutic targets through elaborate in silico approaches,... 

    Effects of Temporal Correlations on Co-infection

    , M.Sc. Thesis Sharif University of Technology Sajjadi, Ebrahim (Author) ; Ejtehadi, Mohammad Reza (Supervisor) ; Ghanbarnejad, Fakhteh (Co-Supervisor)
    Abstract
    SIS and SIR are common models for describing and predicting the epidemics of the contagious diseases. But these models fail to predict patterns of spreading dynamics in the case of co-infective diseases, i.e. getting infected by one disease, alters the chance of getting infected by the other one. Coinfection has been studied in the mean field approximation and on complex networks with different topologies. Another study shows temporal correlations of the underlying transmission network, play role on co-infection dynamics.In this research we investigate the effects of various temporal correlation on epidemic order parameters of independent infection and co-infection.For this purpose, we... 

    Scheduling and Allocation of Pandemic Vaccine Distribution Among Healthcare Centers and High-risk Groups

    , M.Sc. Thesis Sharif University of Technology Fathi, Mohammad Reza (Author) ; Eshghi, Kourosh (Supervisor)
    Abstract
    This study offers a framework to manage mass vaccination programs in response to an outbreak in a city. Compared to previous studies, we consider more operational challenges in the vaccination process; for example, transshipment between vaccinations units and availability of second doses. Our objective function is based on the risk of unvaccinated individuals. Therefore, the model aims at favoring those places in the city where the risk of unvaccinated people is high. Using different kinds of vaccines is another factor that our mathematical model includes. Vaccines are categorized into single-dose and double-dose classes. In this regard, the balanced access to different vaccine types is of... 

    Critical-Item Supply-Chain Using Agent-Based Modelling

    , M.Sc. Thesis Sharif University of Technology Malaek, Mohammad Matin (Author) ; Haji, Alireza (Supervisor)
    Abstract
    One of the crucial matters in the area of Supply Chain Management is the ability of a supply chain to act and react under different circumstances. A helpful tool to understand the supply chain is simulation modeling. With the help of simulation modeling, we can provide the opportunity for the agents in a model to perform based on the defined environment.In the current research, a complete literature review is performed on the topics of supply chain planning and various distribution models and algorithms. With the focus on the vaccine as a critical item, we propose a model to distribute vaccines based on the degree of agents, and we realize that vaccine distribution, while facing huge demand... 

    Green chemistry and coronavirus

    , Article Sustainable Chemistry and Pharmacy ; Volume 21 , 2021 ; 23525541 (ISSN) Ahmadi, S ; Rabiee, N ; Fatahi, Y ; Hooshmand, S. E ; Bagherzadeh, M ; Rabiee, M ; Jajarmi, V ; Dinarvand, R ; Habibzadeh, S ; Saeb, M. R ; Varma, R. S ; Shokouhimehr, M ; Hamblin, M. R ; Sharif University of Technology
    Elsevier B.V  2021
    Abstract
    The novel coronavirus pandemic has rapidly spread around the world since December 2019. Various techniques have been applied in identification of SARS-CoV-2 or COVID-19 infection including computed tomography imaging, whole genome sequencing, and molecular methods such as reverse transcription polymerase chain reaction (RT-PCR). This review article discusses the diagnostic methods currently being deployed for the SARS-CoV-2 identification including optical biosensors and point-of-care diagnostics that are on the horizon. These innovative technologies may provide a more accurate, sensitive and rapid diagnosis of SARS-CoV-2 to manage the present novel coronavirus outbreak, and could be... 

    Green chemistry and coronavirus

    , Article Sustainable Chemistry and Pharmacy ; Volume 21 , 2021 ; 23525541 (ISSN) Ahmadi, S ; Rabiee, N ; Fatahi, Y ; Hooshmand, S. E ; Bagherzadeh, M ; Rabiee, M ; Jajarmi, V ; Dinarvand, R ; Habibzadeh, S ; Saeb, M. R ; Varma, R.S ; Shokouhimehr, M ; Hamblin, M. R ; Sharif University of Technology
    Elsevier B.V  2021
    Abstract
    The novel coronavirus pandemic has rapidly spread around the world since December 2019. Various techniques have been applied in identification of SARS-CoV-2 or COVID-19 infection including computed tomography imaging, whole genome sequencing, and molecular methods such as reverse transcription polymerase chain reaction (RT-PCR). This review article discusses the diagnostic methods currently being deployed for the SARS-CoV-2 identification including optical biosensors and point-of-care diagnostics that are on the horizon. These innovative technologies may provide a more accurate, sensitive and rapid diagnosis of SARS-CoV-2 to manage the present novel coronavirus outbreak, and could be...