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    Efficient one-pot four-component synthesis and X-ray crystallographic structure of 2-pyridone derivatives

    , Article Journal of Heterocyclic Chemistry ; Volume 50, Issue 6 , 2013 , Pages 1272-1280 ; 0022152X (ISSN) Balalaie, S ; Hashemi, M. M ; Khezri, S. H ; Rominger, F ; Ghabraie, E ; Oeser, T ; Sharif University of Technology
    2013
    Abstract
    A series of 3-cyano-2-pyridone derivatives were synthesized by one-pot four-component condensation reaction involving a benzaldehyde derivative, alkyl cyanoacetate, acyclic or cyclic ketones, and ammonium acetate in reflux condition. The X-ray structure of the products 5a and 5d confirm symmetric dimers via hydrogen bonding interactions between individual pyridine molecules showing, in addition, also π-π stacking interactions  
Total 81 records