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Targeting AMPK signaling pathway by natural products for treatment of diabetes mellitus and its complications
, Article Journal of Cellular Physiology ; Volume 234, Issue 10 , 2019 , Pages 17212-17231 ; 00219541 (ISSN) ; Singh, A. K ; Haratipour, P ; Sah, A. N ; Pandey, A. K ; Naseri, R ; Juyal, V ; Farzaei, M. H ; Sharif University of Technology
Wiley-Liss Inc
2019
Abstract
Diabetes affects a large population of the world. Lifestyle, obesity, dietary habits, and genetic factors contribute to this metabolic disease. A target pathway to control diabetes is the 5′-adenosine monophosphate-activated protein kinase (AMPK) signaling pathway. AMPK is a heterotrimeric protein with α, β, and γ subunits. In several studies, AMPK activation enhanced glucose uptake into cells and inhibited intracellular glucose production. Impairment of AMPK activity is present in diabetes, according to some studies. Drugs used in the treatment of diabetes, such as metformin, are also known to act through regulation of AMPK. Thus, drugs that activate and regulate AMPK are potential...
PH-Sensitive stimulus-responsive nanocarriers for targeted delivery of therapeutic agents
, Article Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology ; Volume 8, Issue 5 , 2016 , Pages 696-716 ; 19395116 (ISSN) ; Eslami, M ; Sahandi Zangabad, P ; Mirab, F ; Farajisafiloo, N ; Shafaei, Z ; Ghosh, D ; Bozorgomid, M ; Dashkhaneh, F ; Hamblin, M. R ; Sharif University of Technology
Wiley-Blackwell
2016
Abstract
In recent years miscellaneous smart micro/nanosystems that respond to various exogenous/endogenous stimuli including temperature, magnetic/electric field, mechanical force, ultrasound/light irradiation, redox potentials, and biomolecule concentration have been developed for targeted delivery and release of encapsulated therapeutic agents such as drugs, genes, proteins, and metal ions specifically at their required site of action. Owing to physiological differences between malignant and normal cells, or between tumors and normal tissues, pH-sensitive nanosystems represent promising smart delivery vehicles for transport and delivery of anticancer agents. Furthermore, pH-sensitive systems...
Publishing in predatory open access journals: Authors' perspectives
, Article Learned Publishing ; Volume 33, Issue 2 , 2020 , Pages 89-95 ; Soltani, M ; Tamleh, H ; Teimournezhad, S ; Sharif University of Technology
Wiley-Blackwell
2020
Abstract
The proliferation of predatory or bogus journals has been recognized as a threat to academic research, and this study was conducted to discover the experiences of authors published in these journals. Eighty authors who had published in journals identified as predatory were surveyed. We asked how the authors learnt about these journals, what they thought about the reputation of the journals, their experiences of peer review and the quality of feedback provided, and whether publication was driven by PhD or job requirements. Our results showed that a third of authors discovered the journals by web searches or responding to email invitations. Over half said the reputation and name of the journal...
Plant protein-based hydrophobic fine and ultrafine carrier particles in drug delivery systems
, Article Critical Reviews in Biotechnology ; Volume 38, Issue 1 , 2018 , Pages 47-67 ; 07388551 (ISSN) ; Mirshekari, H ; Sahandi Zangabad, P ; Moosavi Basri, S. M ; Baniasadi, F ; Sharifi Aghdam, M ; Karimi, M ; Hamblin, M. R ; Sharif University of Technology
Taylor and Francis Ltd
2018
Abstract
For thousands of years, plants and their products have been used as the mainstay of medicinal therapy. In recent years, besides attempts to isolate the active ingredients of medicinal plants, other new applications of plant products, such as their use to prepare drug delivery vehicles, have been discovered. Nanobiotechnology is a branch of pharmacology that can provide new approaches for drug delivery by the preparation of biocompatible carrier nanoparticles (NPs). In this article, we review recent studies with four important plant proteins that have been used as carriers for targeted delivery of drugs and genes. Zein is a water-insoluble protein from maize; Gliadin is a 70% alcohol-soluble...
Critical review on fusion welding of magnesium alloys: metallurgical challenges and opportunities
, Article Science and Technology of Welding and Joining ; Volume 26, Issue 8 , 2021 , Pages 559-580 ; 13621718 (ISSN) ; Sharif University of Technology
Taylor and Francis Ltd
2021
Abstract
As the lightest structural alloys, magnesium alloys offer significant potential for improving the energy efficiency of various transportation systems. The lack of sufficient weldability of Mg alloys is a crucial barrier to their potential use in safety-critical applications. Porosity formation, grain structure engineering, solidification cracking, liquation, and liquation cracking are the key metallurgical challenges to obtain reliable and robust fusion welds in Mg alloys. This critical review highlights the current understating regarding controlling the metallurgical phenomena during fusion welding of Mg alloys and discusses the unresolved metallurgical challenges to shed light on the path...
An analytical review on Spark Plasma Sintering of metals and alloys: from processing window, phase transformation, and property perspective
, Article Critical Reviews in Solid State and Materials Sciences ; 2022 ; 10408436 (ISSN) ; Sovizi, S ; Azarniya, A ; Giuntini, D ; Seraji, M. E ; Hosseini, H. R. M ; Amutha, C ; Ramakrishna, S ; Mukasyan, A ; Sharif University of Technology
Taylor and Francis Ltd
2022
Abstract
ABSTRACTs: The need for fully dense material with well-engineered microstructures has led to the promising emergence of innovative sintering technologies among which the Spark Plasma Sintering (SPS) is one of the most favorite. Unlike the conventional sintering processes, SPS takes advantage of a current flow passing through the sintering die and metallic powders by which fast densification with minimal grain growth and enhanced physicomechanical properties can be obtained. Albeit there is a growing interest in the exploitation of SPS in producing sufficiently consolidated metallic parts, no analytical review has been released over the effects of SPS parameters on the densification behavior,...
Niosomal formulation for antibacterial applications
, Article Journal of Drug Targeting ; Volume 30, Issue 5 , 2022 , Pages 476-493 ; 1061186X (ISSN) ; Gharehchelou, B ; Haghighi Poodeh, S ; Jamshidifar, E ; Karimifard, S ; Farasati Far, B ; Akbarzadeh, I ; Seifalian, A ; Sharif University of Technology
Taylor and Francis Ltd
2022
Abstract
Infection is a disease that is mainly caused by different Gram-negative and Gram-positive bacteria. Treatment of infections requires a considerable amount of antibiotics, which can cause serious damage to the patient's body. Delivering the antibiotic only to the site of infection can prevent these destructive effects, such as the destruction of the normal intestinal flora. The drug delivery system through carriers will take antibiotics into a part of the body involved in the disease. Niosome nanoparticles, which have been made from non-ionic surfactants, have been emerging as ideal drug/antibiotics delivery vehicles. Recently, niosome formulations have been targeted to reduce toxicity and...
Processing and properties of nanofibrous bacterial cellulose-containing polymer composites: a review of recent advances for biomedical applications
, Article Polymer Reviews ; Volume 60, Issue 1 , 2020 , Pages 144-170 ; Mahmoodi, A ; Mahmoudi, N ; Zandi, N ; Simchi, A ; Sharif University of Technology
Taylor and Francis Inc
2020
Abstract
Bacterial cellulose (BC) is an extracellular natural polymer produced by many microorganisms and its properties could be tailored via specific fabrication methods and culture conditions. There is a growing interest in BC derived materials due to the main features of BC such as porous fibrous structure, high crystallinity, impressive physico-mechanical properties, and high water content. However, pristine BC lacks some features, limiting its practical use in varied applications. Thus, fabrication of BC composites has been attempted to overcome these constraints. This review article overviews most recent advance in the development of BC composites and their potential in biomedicine including...
Spotlight on kinetic and equilibrium adsorption of a new surfactant onto sandstone minerals: A comparative study
, Article Journal of the Taiwan Institute of Chemical Engineers ; Volume 50 , May , 2015 , Pages 12-23 ; 18761070 (ISSN) ; Ghazanfari, M. H ; Rashtchian, D ; Sharif University of Technology
Taiwan Institute of Chemical Engineers
2015
Abstract
This paper presents a state of the art review of adsorption models for a new plant-based surfactant adsorption onto sandstone minerals. The adsorption data at both kinetic and equilibrium modes were obtained from batch experiments. Four adsorption kinetic models, five two-parameter, and six three-parameter equilibrium models were used for interpretation of the obtained data. Among the two and three-parameter isotherm models applied, the Jovanovic and the Khan isotherms showed the best fit, respectively. And the pseudo-second order model presented a better fit than other kinetic models. Finally, a computer-based modeling approach was developed and used for predicting the kinetics of...
An improvement in the determination of end bearing capacity of drilled shafts in sand
, Article Journal of GeoEngineering ; Volume 14, Issue 2 , 2019 , Pages 109-119 ; 19908326 (ISSN) ; Jazebi, M ; Sharif University of Technology
Taiwan Geotechnical Society
2019
Abstract
There are many equations available in the literature using the results of CPT (cone penetration test) and SPT (standard penetration test) measurements to predict the end bearing capacity of drilled shafts in sand. However, there are few equations that use soil parameters, such as friction angle and elastic modulus, as input values. Also, these available equations usually overestimate the end bearing capacity, and at times show conflicting results with respect to the parameters they use. This paper describes a numerical procedure to overcome the above shortcomings. The results obtained in this study were compared with both experimental and numerical results available in the literature. A...
An improvement in the determination of end bearing capacity of drilled shafts in sand
, Article Journal of GeoEngineering ; Volume 14, Issue 2 , 2019 , Pages 109-119 ; 19908326 (ISSN) ; Jazebi, M ; Sharif University of Technology
Taiwan Geotechnical Society
2019
Abstract
There are many equations available in the literature using the results of CPT (cone penetration test) and SPT (standard penetration test) measurements to predict the end bearing capacity of drilled shafts in sand. However, there are few equations that use soil parameters, such as friction angle and elastic modulus, as input values. Also, these available equations usually overestimate the end bearing capacity, and at times show conflicting results with respect to the parameters they use. This paper describes a numerical procedure to overcome the above shortcomings. The results obtained in this study were compared with both experimental and numerical results available in the literature. A...
Inorganic nanomaterials for chemo/photothermal therapy: a promising horizon on effective cancer treatment
, Article Biophysical Reviews ; Volume 11, Issue 3 , 2019 , Pages 335-352 ; 18672450 (ISSN) ; Zamani, M ; Golizadeh, M ; Bavi, O ; Sharif University of Technology
Springer Verlag
2019
Abstract
During the last few decades, nanotechnology has established many essential applications in the biomedical field and in particular for cancer therapy. Not only can nanodelivery systems address the shortcomings of conventional chemotherapy such as limited stability, non-specific biodistribution and targeting, poor water solubility, low therapeutic indices, and severe toxic side effects, but some of them can also provide simultaneous combination of therapies and diagnostics. Among the various therapies, the combination of chemo- and photothermal therapy (CT-PTT) has demonstrated synergistic therapeutic efficacies with minimal side effects in several preclinical studies. In this regard,...
Finite element simulation of ultrasonic-assisted machining: a review
, Article International Journal of Advanced Manufacturing Technology ; Volume 116, Issue 9-10 , 2021 , Pages 2777-2796 ; 02683768 (ISSN) ; Akbari, J ; Sharif University of Technology
Springer Science and Business Media Deutschland GmbH
2021
Abstract
Ultrasonic-assisted machining is an advanced method which could improve the process of machining. Besides, simulation modeling process is a method to help the researchers analyze different aspects of the process with more details in a shorter time. Simulation of ultrasonic-assisted machining is also a field of research that is of interest to researchers working in the field of machining processes. In recent years, a variety of papers have been published where cutting forces, chip formation, tool wear and temperature, and microstructure changes were simulated. That being the case, a review paper is required to represent the advances implemented by researchers in the simulation of...
Laboratory detection methods for the human coronaviruses
, Article European Journal of Clinical Microbiology and Infectious Diseases ; Volume 40, Issue 2 , 2021 , Pages 225-246 ; 09349723 (ISSN) ; Dowlatshahi, S ; Abdekhodaie, M. J ; Sharif University of Technology
Springer Science and Business Media Deutschland GmbH
2021
Abstract
Coronaviruses are a group of envelop viruses which lead to diseases in birds and mammals as well as human. Seven coronaviruses have been discovered in humans that can cause mild to lethal respiratory tract infections. HCoV-229E, HCoV-OC43, HCoV-NL63, and HCoV-HKU1 are the low-risk members of this family and the reason for some common colds. Besides, SARS-CoV, MERS-CoV, and newly identified SARS-CoV-2, which is also known as 2019-nCoV, are the more dangerous viruses. Due to the rapid spread of this novel coronavirus and its related disease, COVID-19, a reliable, simple, fast, and low-cost detection method is necessary for patient diagnosis and tracking worldwide. Human coronaviruses detection...
Unraveling cancer metastatic cascade using microfluidics-based technologies
, Article Biophysical Reviews ; Volume 14, Issue 2 , 2022 , Pages 517-543 ; 18672450 (ISSN) ; Kermanshah, L ; Abouali, H ; Hashemi, H. M ; Yari, A ; Khorasheh, F ; Alemzadeh, I ; Vossoughi, M ; Sharif University of Technology
Springer Science and Business Media Deutschland GmbH
2022
Abstract
Cancer has long been a leading cause of death. The primary tumor, however, is not the main cause of death in more than 90% of cases. It is the complex process of metastasis that makes cancer deadly. The invasion metastasis cascade is the multi-step biological process of cancer cell dissemination to distant organ sites and adaptation to the new microenvironment site. Unraveling the metastasis process can provide great insight into cancer death prevention or even treatment. Microfluidics is a promising platform, that provides a wide range of applications in metastasis-related investigations. Cell culture microfluidic technologies for in vitro modeling of cancer tissues with fluid flow and the...
A novel viewpoint to the green city concept based on vegetation area changes and contributions to healthy days: a case study of Mashhad, Iran
, Article Environmental Science and Pollution Research ; Volume 29, Issue 1 , 2022 , Pages 702-710 ; 09441344 (ISSN) ; Makian, M ; Gheibi, M ; Fathollahi Fard, A. M ; Sharif University of Technology
Springer Science and Business Media Deutschland GmbH
2022
Abstract
One of the significant challenges in urbanization is the air pollution. This highlights the need of the green city concept with reconsideration of houses, factories, and traffic in a green viewpoint. The literature review confirms that this reconsideration for green space has a positive effect on the air quality of large cities and to reduce the air pollution. The purpose of this study is to evaluate the annual vegetation changes in the green space of Mashhad, Iran as a very populated city in the middle east to study the air pollution. To investigate the relationship between the air pollution and vegetation, the Landsat 8 satellite images for summer seasons of 2013–2019 were used to extract...
Gold-based hybrid nanostructures: more than just a pretty face for combinational cancer therapy
, Article Biophysical Reviews ; Volume 14, Issue 1 , 2022 , Pages 317-326 ; 18672450 (ISSN) ; Bavi, O ; Zamani, M ; Sharif University of Technology
Springer Science and Business Media Deutschland GmbH
2022
Abstract
The early diagnosis together with an efficient therapy of cancer is essential to treat cancer patients and to enhance their quality of life. The use of nanostructures, as a newer technology, has demonstrated proven benefits as efficient cancer theranostic agents in numerous recent studies. Having a tunable surface plasmon resonance, gold nanostructures have been the subject of many recent studies as excellent imaging and photothermal therapy agents. However, the potential cytotoxicity and weak stability of gold nanostructures necessitate further modifications using biocompatible materials for biological applications. Based on the composition of the final structure, these gold-based hybrid...
The role of the gut microbiota and nutrition on spatial learning and spatial memory: a mini review based on animal studies
, Article Molecular Biology Reports ; Volume 49, Issue 2 , 2022 , Pages 1551-1563 ; 03014851 (ISSN) ; Noori, S. M. R ; Samarbafzadeh, E ; Noori, S. M. A ; Sharif University of Technology
Springer Science and Business Media B.V
2022
Abstract
The gut-brain axis is believed to constitute a bidirectional communication mechanism that affects both mental and digestive processes. Recently, the role of the gut microbiota in cognitive performance has been the focus of much research. In this paper, we discuss the effects of gut microbiota and nutrition on spatial memory and learning. Studies have shown the influence of diet on cognitive capabilities such as spatial learning and memory. It has been reported that a high-fat diet can alter gut microbiota which subsequently leads to changes in spatial learning and memory. Some microorganisms in the gut that can significantly affect spatial learning and memory are Akkermansia muciniphila,...
Effect of vibration on postural control and gait of elderly subjects: a systematic review
, Article Aging Clinical and Experimental Research ; Volume 30, Issue 7 , 2018 , Pages 713-726 ; 15940667 (ISSN) ; Arazpour, M ; Bahramizadeh, M ; Farahmand, F ; Fadayevatan, R ; Sharif University of Technology
Springer International Publishing
2018
Abstract
Background and aim: Gait and balance disorders are common in the elderly populations, and their prevalence increases with age. This systematic review was performed to summarize the current evidence for subthreshold vibration interventions on postural control and gait in elderly. Method: A review of intervention studies including the following words in the title/abstract: insole, foot and ankle appliances, vibration, noise and elderly related to balance and gait. Databases searched included PubMed, ISI Web of Knowledge, Ovid, Scopus, and Google Scholar. Fifteen articles were selected for final evaluation. The procedure was followed using the preferred reporting items for systematic reviews...
Recent advances in the design and applications of amyloid-β peptide aggregation inhibitors for Alzheimer’s disease therapy
, Article Biophysical Reviews ; Volume 11, Issue 6 , 2019 , Pages 901-925 ; 18672450 (ISSN) ; Khazaei, S ; Behnammanesh, H ; Shamloo, A ; Erfani, M ; Beiki, D ; Bavi, O ; Sharif University of Technology
Springer
2019
Abstract
Alzheimer’s disease (AD) is an irreversible neurological disorder that progresses gradually and can cause severe cognitive and behavioral impairments. This disease is currently considered a social and economic incurable issue due to its complicated and multifactorial characteristics. Despite decades of extensive research, we still lack definitive AD diagnostic and effective therapeutic tools. Consequently, one of the most challenging subjects in modern medicine is the need for the development of new strategies for the treatment of AD. A large body of evidence indicates that amyloid-β (Aβ) peptide fibrillation plays a key role in the onset and progression of AD. Recent studies have reported...