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    Biomechanical Analysis of the Effects of L4-L5 Fusion Surgery on Adjacent Segments Using Musculoskeletal and Finite Element Modeling

    , Ph.D. Dissertation Sharif University of Technology Ebrahimkhani, Mahdi (Author) ; Arjmand, Navid (Supervisor) ; Shirazi Adl, Aboulfazl (Co-Supervisor)
    Abstract
    Background: Degeneration of intervertebral joints due to kinetical alterations after fusion surgery is a prevalent back disorder. While in-vivo studies are limited to medical imaging techniques, in-vitro and in-silico (passive FE modeling) investigations lack the crucial role of muscle forces. Available musculoskeletal modeling studies, not only suffer oversimplification of intervertebral joints, but have some shortcomings in incorporation of the contributing factors (that may alter postoperative kinetics). On the other hand, one of the main shortcomings in the available musculoskeletal models is their inability to account for dynamic effects and modeling transient events. Purpose: 1-... 

    A Comprehensive Approach for the Validation of Lumbar Spine Finite Element Models Investigating Post-Fusion Adjacent Segment Effects

    , M.Sc. Thesis Sharif University of Technology Azadi, Amir Hossein (Author) ; Arjomand, Navid (Supervisor)
    Abstract
    Spinal fusion surgery is usually followed by accelerated degenerative changes in the unfused segments above and below the treated segment(s), i.e., adjacent segment disease (ASD). While a number of risk factors for ASD have been suggested, its exact pathogenesis remains to be identified. Finite element (FE) models are indispensable tools to investigate mechanical effects of fusion surgeries on post-fusion changes in the adjacent segment kinematics and kinetics. Existing modeling studies validate only their intact FE model against in vitro data and subsequently simulate post-fusion in vivo conditions. The present study provides a novel approach for the comprehensive validation of a lumbar... 

    A Detailed Nonlinear Finite Element Model of the L4-L5 Motion Segment to Predcit Spinal Loads during in Vivo Activities

    , M.Sc. Thesis Sharif University of Technology Azari, Fahime (Author) ; Arjmand, Navid (Supervisor) ; Parnianpour, Mohammad (Supervisor)
    Abstract
    Several geometrically-detailed passive finite element (FE) models of the lumbar spine have been developed and validated under in vitro loading conditions. As these models are devoid of muscles, they are either not used to simulate in vivo activities or muscle forces are modeled by a hypothetical compressive follower load (FL). A number of symmetric and asymmetric static tasks were first simulated using a validated musculoskeletal model of the thoracolumbar spine to predict trunk muscle forces. The predicted muscle forces along with the gravity loading were then applied to a passive FE model of the L4-L5 motion segment (developed and validated here) to estimate load sharing among the disc,... 

    Sparse and low-rank recovery using adaptive thresholding

    , Article Digital Signal Processing: A Review Journal ; Volume 73 , 2018 , Pages 145-152 ; 10512004 (ISSN) Zarmehi, N ; Marvasti, F ; Sharif University of Technology
    Elsevier Inc  2018
    Abstract
    In this paper, we propose an algorithm for recovery of sparse and low-rank components of matrices using an iterative method with adaptive thresholding. In each iteration of the algorithm, the low-rank and sparse components are obtained using a thresholding operator. The proposed algorithm is fast and can be implemented easily. We compare it with the state-of-the-art algorithms. We also apply it to some applications such as background modeling in video sequences, removing shadows and specularities from face images, and image restoration. The simulation results show that the proposed algorithm has a suitable performance with low run-time. © 2017 Elsevier Inc  

    Correlation and prediction of small to large sized pharmaceuticals solubility, and crystallization in binary and ternary mixed solvents using the UNIQUAC-SAC model

    , Article Fluid Phase Equilibria ; Volume 519 , 2020 Yousefi Seyf, J ; Asgari, M ; Sharif University of Technology
    Elsevier B.V  2020
    Abstract
    The recently reported UNIversal QUAsiChemical Segment Activity coefficient (UNIQUAC-SAC) model [developed by Haghtalab and Yousefi Seyf Ind. Eng. Chem. Res. 2015, 54, 8611] provides a practical thermodynamic framework to be used in VLE, LLE, and SLE calculations. The UNIQUAC-SAC model has the advantage of being independent of area (q) and volume (r) structural parameters used in the combinatorial part. While the UNIFAC or UNIFAC-DMD could not apply to the 47% (44 of 94) of the studied molecules because of the undefined groups. Here, the numbers of solvents with identified segment numbers were extended from 82 to 130 with a slight refinement to the previous values. The model parameters... 

    An optimization based approach embedded in a fuzzy connectivity algorithm for airway tree segmentation

    , Article Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology", 20 August 2008 through 25 August 2008, Vancouver, BC ; 2008 , Pages 4011-4014 ; 9781424418152 (ISBN) Yousefi Rizi, F ; Ahmadian, A. R ; Fatemizadeh, E ; Alirezaie, J ; Sharif University of Technology
    2008
    Abstract
    The main problem with airway segmentation methods which significantly influences their accuracy is leakage into the extra-luminal regions due to thinness of the airway wall during the process of segmentation. This phenomenon potentially makes large regions of lungparenchyma to be wrongly identified as airways. A solution to this problem in the previous methods was based on leak detection followed by reducing leakage during the segmentation process. This has been dealt with adjusting the segmentation parameters and performing the re-segmentation process on the pre-segmented area. This makes the algorithm very exhaustive and more dependent on the user interaction. The method presented here is... 

    A hybrid fuzzy based algorithm for 3D human airway segmentation

    , Article 2nd International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2008, Shanghai, 16 May 2008 through 18 May 2008 ; 2008 , Pages 2295-2298 ; 9781424417483 (ISBN) Yousefi Rizi, F ; Ahmadian, A ; Sahba, N ; Tavakoli, V ; Alirezaie, J ; Fatemizadeh, E ; Rezaie, N ; Sharif University of Technology
    IEEE Computer Society  2008
    Abstract
    Segmentation of the human airway tree from volumetric computed tomography images is an important stage for many clinical applications such as virtual bronchoscopy. The main challenges of previously developed methods are to deal with two problems namely, leaking into the surrounding lung parenchyma during segmentation and the need to manually adjust the parameters. To overcome these problems, a multi-seeded fuzzy based region growing approach in conjuction with the spatial information of voxels is proposed. Comparison with a commonly used region growing segmentation algorithm shows that the proposed method retrieves more accurate results by achieving the specificity and sensitivity of 98.81%... 

    Esophageal gross tumor volume segmentation using a 3D convolutional neural network

    , Article Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 16 September 2018 through 20 September 2018 ; Volume 11073 LNCS , 2018 , Pages 343-351 ; 03029743 (ISSN); 9783030009366 (ISBN) Yousefi, S ; Sokooti, H ; Elmahdy, M. S ; Peters, F. P ; Manzuri Shalmani, M. T ; Zinkstok, R. T ; Staring, M ; Sharif University of Technology
    Springer Verlag  2018
    Abstract
    Accurate gross tumor volume (GTV) segmentation in esophagus CT images is a critical task in computer aided diagnosis (CAD) systems. However, because of the difficulties raised by the contrast similarity between esophageal GTV and its neighboring tissues in CT scans, this problem has been addressed weakly. In this paper, we present a 3D end-to-end method based on a convolutional neural network (CNN) for this purpose. We leverage design elements from DenseNet in a typical U-shape. The proposed architecture consists of a contractile path and an extending path that includes dense blocks for extracting contextual features and retrieves the lost resolution respectively. Using dense blocks leads to... 

    A new image texture extraction algorithm based on Matching Pursuit Gabor wavelets

    , Article 2005 IEEE International Conference on Acoustics, Speech, and Signal Processing, ICASSP '05, Philadelphia, PA, 18 March 2005 through 23 March 2005 ; Volume II , 2005 , Pages II740-II744 ; 15206149 (ISSN); 0780388747 (ISBN); 9780780388741 (ISBN) Yaghoobi, M ; Rabiee, H. R ; Ghanbari, M ; Shamsollahi, M. B ; Sharif University of Technology
    2005
    Abstract
    Feature vector extraction, based on local image texture, is a primitive algorithm for many other applications, like segmentation, clustering and identification. If these feature vectors are a good match to the human visual system (HVS), we can expect to get the appropriate results by using them. Gabor filters has been used for this purpose successfully. In this paper we introduce a novel refinement, with the use of Matching Pursuit (MP) to improve the Gabor based texture feature extractor. With this improvement, we show that the separability of different textures will increase. Another consideration in this work is computation complexity. Therefore, we limit the basis function set to reduce... 

    Introducing a new method for estimation image complexity according to calculate watermark capacity

    , Article 2008 4th International Conference on Intelligent Information Hiding and Multiedia Signal Processing, IIH-MSP 2008, Harbin, 15 August 2008 through 17 August 2008 ; 2008 , Pages 981-984 ; 9780769532783 (ISBN) Yaghmaee, F ; Jamzad, M ; Sharif University of Technology
    2008
    Abstract
    One of the most important parameters in evaluating a watermarking algorithm is its capacity. In fact, capacity has a paradoxical relation with other two important parameters: image quality and robustness. Some works have been done on watermarking capacity and a few on image complexities. Most works on watermarking capacity is based on information theory and the capacity values which are calculated based on these methods are very tolerate. In this paper we propose a new method for calculating image complexity based on Region Of Interest (ROI) concept. After that we analyze three complexity measures named: Image compositional complexity (ICC), Quad tree and ROI method, with three different... 

    Preoperative paraspinal neck muscle characteristics predict early onset adjacent segment degeneration in anterior cervical fusion patients: A machine-learning modeling analysis

    , Article Journal of Orthopaedic Research ; 2020 Wong, A. Y. L ; Harada, G ; Lee, R ; Gandhi, S. D ; Dziedzic, A ; Espinoza Orias, A ; Parnianpour, M ; Louie, P. K. H ; Basques, B ; An, H. S ; Samartzis, D ; Sharif University of Technology
    John Wiley and Sons Inc  2020
    Abstract
    Early onset adjacent segment degeneration (ASD) can be found within six months after anterior cervical discectomy and fusion (ACDF). Deficits in deep paraspinal neck muscles may be related to early onset ASD. This study aimed to determine whether the morphometry of preoperative deep neck muscles (multifidus and semispinalis cervicis) predicted early onset ASD in patients with ACDF. Thirty-two cases of early onset ASD after a two-level ACDF and 30 matched non-ASD cases were identified from a large-scale cohort. The preoperative total cross-sectional area (CSA) of bilateral deep neck muscles and the lean muscle CSAs from C3 to C7 levels were measured manually on T2-weighted magnetic resonance... 

    Search for critical loading condition of the spine-A meta analysis of a nonlinear viscoelastic finite element model

    , Article Computer Methods in Biomechanics and Biomedical Engineering ; Volume 8, Issue 5 , 2005 , Pages 323-330 ; 10255842 (ISSN) Wang, J. L ; Shirazi Adl, A ; Parnianpour, M ; Sharif University of Technology
    2005
    Abstract
    The relative vulnerability of spinal motion segments to different loading combinations remains unknown. The meta-analysis described here using the results of a validated L2-L3 nonlinear viscoelastic finite element model was designed to investigate the critical loading and its effect on the internal mechanics of the human lumbar spine. A Box-Behnken experimental design was used to design the magnitude of seven independent variables associated with loads, rotations and velocity of motion. Subsequently, an optimization method was used to find the primary and secondary variables that influence spine mechanical output related to facet forces, disc pressure, ligament forces, annulus matrix... 

    Hidden-Markov-model-based voice activity detector with high speech detection rate for speech enhancement

    , Article IET Signal Processing ; Volume 6, Issue 1 , February , 2012 , Pages 54-63 ; 17519675 (ISSN) Veisi, H ; Sameti, H ; Sharif University of Technology
    2012
    Abstract
    A new voice activity detection (VAD) algorithm with soft decision output in Mel-frequency domain is developed based on hidden Markov model (HMM) and is incorporated in an HMM-based speech enhancement system. The proposed VAD uses a two-state ergodic HMM representing speech presence and speech absence. The states are constructed from noisy speech and noise HMMs used in the speech enhancement system. This composite model provides a robust detection of speech segments in the presence of noise and obviates the need for extra modeling in HMM-based speech enhancement applications. As the main purpose of the proposed VAD is to detect speech segments accurately, a hang-over mechanism is proposed and... 

    Comparing methods for 3d inverse dynamics analysis of squat lifting using a full body linked segment model

    , Article Journal of Mechanics in Medicine and Biology ; Volume 20, Issue 3 , 2020 Vahdat, I ; Parnianpour, M ; Tabatabai Ghomsheh, F. T ; Toosizadeh, N ; Tanbakoosaz, A. L. I ; Sharif University of Technology
    World Scientific Publishing Co. Pte Ltd  2020
    Abstract
    Objective: The main objective of this study was to assess the accuracy of bottom-up solution for three-dimensional (3D) inverse dynamics analysis of squat lifting using a 3D full body linked segment model. Least squares solution was used in this study as reference for assessment of the accuracy of bottom-up solution. Findings of this study may clarify how much the bottom-up solution can be reliable for calculating the joint kinetics in 3D inverse dynamics problems. Methods: Ten healthy males volunteered to perform squat lifting of a box with a load of one-Tenth of their body weights. The joint moments were calculated using 110 reflective passive markers (46 anatomical markers and 64 tracking... 

    Price, delivery time, and capacity decisions in an M/M/1 make-to-order/service system with segmented market

    , Article International Journal of Advanced Manufacturing Technology ; Volume 57, Issue 1-4 , 2011 , Pages 235-244 ; 02683768 (ISSN) Teimoury, E ; Modarres, M ; Monfared, A. K ; Fathi, M ; Sharif University of Technology
    2011
    Abstract
    Speed and price are the two most important factors in customer satisfaction and business success in today's competitive environment. Time-based product differentiation and segment pricing have provided firms with a great opportunity to profit enhancement. This paper presents a coding system for pricing/queuing models in the literature. In this article, a service/make-to-order firm with heterogeneous price and delivery time-sensitive customers as an M/M/1 queuing system is analyzed. The firm uses customers' heterogeneity to create market segments. Products offered to each segment differ only in price and delivery time. The objective of this profit-maximizing firm is to determine optimal... 

    Color Image Segmentation Using a Fuzzy Inference System

    , Article 7th International Conference on Digital Information Processing and Communications, ICDIPC 2019, 2 May 2019 through 4 May 2019 ; 2019 , Pages 78-83 ; 9781728132969 (ISBN) Tehrani, A. K. N ; Macktoobian, M ; Kasaei, S ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2019
    Abstract
    A novel method is proposed in the scope of image segmentation that solves this problem by breaking it into two main blocks. The first block's functionality is a method to anticipate the color basis of each segment in segmented images. One of the challenges of image segmentation is the inappropriate distribution of colors in the RGB color space. To determine the color of each segment, after mapping the input image onto the HSI color space, the image colors are classified into some clusters by exploiting the K-Means. Then, the list of cluster centers is winnowed down to a short list of colors based on a set of criteria. The second block of the proposed method defines how each pixel of the... 

    Evaluation of the topographical surface changes of silicon wafers after annealing and plasma cleaning

    , Article Silicon ; Volume 12, Issue 11 , 2020 , Pages 2563-2570 Stach, S ; Ţălu, Ş ; Dallaev, R ; Arman, A ; Sobola, D ; Salerno, M ; Sharif University of Technology
    Springer Science+Business Media B.V  2020
    Abstract
    Purpose: The morphological stability of silicon single crystal wafers was investigated, after performing cleaning surface treatments based on moderate temperature annealing and plasma sputtering. Methods: The wafer surfaces were measured by Tapping mode atomic force microscopy in air, before and after the different treatments. The 3D images were segmented by watershed algorithm identifying the local peaks, and the stereometric parameters were extracted thereof. The analysis of variance allowed to better assess the statistically significant differences. Results: All the resulting quantities were critically discussed. It appeared that the different cleaning treatments affected differently the... 

    Finding arbitrary shaped clusters and color image segmentation

    , Article 1st International Congress on Image and Signal Processing, CISP 2008, Sanya, Hainan, 27 May 2008 through 30 May 2008 ; Volume 1 , 2008 , Pages 593-597 ; 9780769531199 (ISBN) Soleymani Baghshah, M ; Bagheri Shouraki, S ; Sharif University of Technology
    2008
    Abstract
    One of the most famous approaches for the segmentation of color images is finding clusters in the color space. Shapes of these clusters are often complex and the time complexity of the existing algorithms for finding clusters of different shapes is usually high. In this paper, a novel clustering algorithm is proposed and used for the image segmentation purpose. This algorithm distinguishes clusters of different shapes using a two-stage clustering approach in a reasonable time. In the first stage, the mean-shift clustering algorithm is used and the data points are grouped into some sub-clusters. In the second stage, connections between sub-clusters are established according to a dissimilarity... 

    A model-based approach for estimation of changes in lumbar segmental kinematics associated with alterations in trunk muscle forces

    , Article Journal of Biomechanics ; 2017 ; 00219290 (ISSN) Shojaei, I ; Arjmand, N ; Meakin, J. R ; Bazrgari, B ; Sharif University of Technology
    Elsevier Ltd  2017
    Abstract
    The kinematics information from imaging, if combined with optimization-based biomechanical models, may provide a unique platform for personalized assessment of trunk muscle forces (TMFs). Such a method, however, is feasible only if differences in lumbar spine kinematics due to differences in TMFs can be captured by the current imaging techniques. A finite element model of the spine within an optimization procedure was used to estimate segmental kinematics of lumbar spine associated with five different sets of TMFs. Each set of TMFs was associated with a hypothetical trunk neuromuscular strategy that optimized one aspect of lower back biomechanics. For each set of TMFs, the segmental... 

    A model-based approach for estimation of changes in lumbar segmental kinematics associated with alterations in trunk muscle forces

    , Article Journal of Biomechanics ; Volume 70 , March , 2018 , Pages 82-87 ; 00219290 (ISSN) Shojaei, I ; Arjmand, N ; Meakin, J ; Bazrgari, B ; Sharif University of Technology
    Elsevier Ltd  2018
    Abstract
    The kinematics information from imaging, if combined with optimization-based biomechanical models, may provide a unique platform for personalized assessment of trunk muscle forces (TMFs). Such a method, however, is feasible only if differences in lumbar spine kinematics due to differences in TMFs can be captured by the current imaging techniques. A finite element model of the spine within an optimization procedure was used to estimate segmental kinematics of lumbar spine associated with five different sets of TMFs. Each set of TMFs was associated with a hypothetical trunk neuromuscular strategy that optimized one aspect of lower back biomechanics. For each set of TMFs, the segmental...