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Total 292 records

    Influence of cold-rolling reduction on retained austenite texture in cold-rolled and intercritically annealed TRIP-assisted steel

    , Article Journal of Applied Crystallography ; Volume 44, Issue 6 , 2011 , Pages 1190-1197 ; 00218898 (ISSN) Emadoddin, E ; Akbarzadeh, A ; Petrov, R ; Kestens, L ; Pirgazi, H ; Sharif University of Technology
    2011
    Abstract
    The newly developed multiphase transformation-induced plasticity (TRIP) steels are of interest for industrial applications because of their excellent combination of high strength and ductility. Their performance can be successfully controlled by designing an optimum balance in the volume fractions of ferrite, bainite and retained austenite. The characteristics of the retained austenite are considered to be the main key to achieving the desired final properties. Against this background, the effects of retained austenite characteristics, such as volume fraction, carbon concentration, size and shape, on the behaviour of TRIP steels have been studied. The crystallographic orientation of the... 

    Multi sensing grasper for minimally invasive surgery

    , Article IEEE/ASME International Conference on Advanced Intelligent Mechatronics, AIM, 3 July 2011 through 7 July 2011, Budapest ; July , 2011 , Pages 344-349 ; 9781457708381 (ISBN) Fattahi, S. J ; Zabihollah, A ; Adldoost, H ; Sharif University of Technology
    2011
    Abstract
    In the present work, a multi sensing grasper has been developed for minimally invasive surgery with embedded ZnO piezoelectric and Fiber Bragg Grating sensors. In this model, a sensing patch equipped with three FBG sensors to sense the temperature in rage of 800 n.m and two separated FBG in range of 1550 m.m to detect the displacement in x and y directions. ZnO piezoelectric is highly sensitive to time and provides a good resistance to temperature. Therefore, this sensor is used for measuring the rate of strain and creep coefficient. A finite element approach based on the viscous material theory and plane displacement theory of anisotropic materials has been utilized to obtain the compliance... 

    Crude oil desalter effluent treatment by a hybrid UF/RO membrane separation process

    , Article Desalination ; Volume 238, Issue 1-3 , 2009 , Pages 174-182 ; 00119164 (ISSN) Norouzbahari, S ; Roostaazad, R ; Hesampour, M ; Sharif University of Technology
    2009
    Abstract
    Crude oil desalter effluent from a Tehran oil refinery was treated by a hybrid UF/RO membrane separation process. Ultrafiltration (UF) was used primarily to remove the emulsified oil droplets followed by the removal of total dissolved solids (TDS) via reverse osmosis (RO). The UF membrane was a hydrophilic flat sheet polysulfone ultrafiltration membrane with MWCO of 100 kDa while the RO membrane was a spiral-wound thin-film composite polyamide. Effect of operating conditions such as transmembrane pressure and crossflow velocity were studied in UF pretreatment. The experimental results showed that the UF membrane removed more than 75% of the oil and can be considered as an effective... 

    The effect of bainite morphology on the mechanical properties of a high bainite dual phase (HBDP) steel

    , Article Materials Science and Engineering A ; Volume 525, Issue 1-2 , 2009 , Pages 159-165 ; 09215093 (ISSN) Bakhtiari, R ; Ekrami, A ; Sharif University of Technology
    2009
    Abstract
    4340 steel bars were austenitized at 850 °C for 1 h followed by heating at 700 °C for 90 min and quenching into a salt bath at the temperature range of 300-450 °C for 1 h to obtain dual structures with 34 vol.% fraction ferrite and various bainite morphologies. SEM studies showed that by increasing the austempering temperature, bainite morphology varies from lower to upper bainite. Tensile, impact and hardness tests revealed that increasing the austempering temperature from 300 to 400 °C leads to a reduction in yield and ultimate tensile strength, hardness, uniform and total elongation and impact energy. But in dual phase steel produced by austempering at 450 °C, yield and tensile strength... 

    Design of peptide-based inhibitor agent against amyloid-β aggregation: Molecular docking, synthesis and in vitro evaluation

    , Article Bioorganic Chemistry ; Volume 102 , September , 2020 Jokar, S ; Erfani, M ; Bavi, O ; Khazaei, S ; Sharifzadeh, M ; Hajiramezanali, M ; Beiki, D ; Shamloo, A ; Sharif University of Technology
    Academic Press Inc  2020
    Abstract
    Formation of the amyloid beta (Aβ) peptide aggregations represents an indispensable role in appearing and progression of Alzheimer disease. β-sheet breaker peptides can be designed and modified with different amino acids in order to improve biological properties and binding affinity to the amyloid beta peptide. In the present study, three peptide sequences were designed based on the hopeful results of LIAIMA peptide and molecular docking studies were carried out onto the monomer and fibril structure of amyloid beta peptide using AutoDock Vina software. According to the obtained interactions and binding energy from docking, the best-designed peptide (D-GABA-FPLIAIMA) was chosen and... 

    Virtual address space mapping for IP auto-configuration in MANET with security capability

    , Article Proceedings of the 2008 International Conference on Advanced Infocomm Technology, ICAIT '08, 29 July 2008 through 31 July 2008, Shenzhen ; 2008 ; 9781605580883 (ISBN) Taghiloo, M ; Tajamolian, M ; Dehghan, M ; Mousavi, R ; Sharif University of Technology
    2008
    Abstract
    Mobile Ad Hoc Networks (MANETs) are networks with selforganizing capabilities and without a fixed infrastructure. Wireless nodes communicate among themselves using multi-hop radio relaying, without requiring the packets to pass through a central access point or a base station. In a highly mobile and infrastructure-less scenario, pre-configuration of addresses is not possible. Therefore node addresses need to be configured dynamically with minimum delay and packet loss. Existing solutions for IP address auto-configuration do not address security issues. In this paper we propose a secure address autoconfiguration for Mobile Ad hoc Networks (MANET) based on Virtual Address Space Mapping [1].... 

    Amyloid fibril reduction through covalently modified lysine in HEWL and insulin

    , Article Archives of Biochemistry and Biophysics ; Volume 727 , 2022 ; 00039861 (ISSN) Rezaei, M ; Kalhor, H. R ; Sharif University of Technology
    Academic Press Inc  2022
    Abstract
    Proteins possess a variety of nucleophiles, which can carry out different reactions in the functioning cells. Proteins endogenously and synthetically can be modified through their nucleophilic sites. The roles of these chemical modifications have not been completely revealed. These modifications can alter the protein folding process. Protein folding directly affects the function of proteins. If an error in protein folding occurs, it may cause protein malfunction leading to several neurodegenerative disorders such as Alzheimer's and Parkinson's. In this study, Hen Egg White Lysozyme (HEWL) and bovine insulin, as model proteins for studying the amyloid formation, were covalently attached with... 

    Subsonic and supersonic flow-induced vibration of sandwich cylindrical shells with FG-CNT reinforced composite face sheets and metal foam core

    , Article International Journal of Mechanical Sciences ; Volume 215 , 2022 ; 00207403 (ISSN) Taati, E ; Fallah, F ; Ahmadian, M. T ; Sharif University of Technology
    Elsevier Ltd  2022
    Abstract
    Based on the linear fluid-solid interaction (FSI) model and classical shell theories, vibration behavior of sandwich cylindrical shells subjected to external incompressible or compressible fluid flow is investigated. The sandwich shell includes the same outer and inner face sheets made of carbon nanotube (CNT) reinforced composites and a metal foam core. The effective mechanical properties of CNT reinforced composites are obtained using the extended rule of mixture. Also, the porosity distribution through the foam thickness is assumed to be in the form of a trigonometric function. Equations of motion and corresponding boundary conditions are derived according to the Donnell's, Love's and... 

    Polyaniline-nylon-6 electrospun nanofibers for headspace adsorptive microextraction

    , Article Analytica Chimica Acta ; Volume 713 , 2012 , Pages 63-69 ; 00032670 (ISSN) Bagheri, H ; Aghakhani, A ; Sharif University of Technology
    2012
    Abstract
    A headspace adsorptive microextraction technique was developed using a novel polyaniline-nylon-6 (PANI-N6) nanofiber sheet, fabricated by electrospinning. The homogeneity and the porosity of the prepared PANI-N6 sheet were studied using the scanning electron microscopy (SEM) and nanofibers diameters were found to be around 200nm. The novel nanofiber sheet was examined as an extracting medium to isolate some selected chlorobenzenes (CBs), as model compounds, from aquatic media. The extracted analytes were desorbed using μL-amounts of solvent and eventually an aliquot of extractant was injected into gas chromatography-mass spectrometry (GC-MS). Various parameters affecting the extraction and... 

    A new flat sheet membrane bioreactor hybrid system for advanced treatment of effluent, reverse osmosis pretreatment and fouling mitigation

    , Article Bioresource Technology ; Volume 192 , 2015 , Pages 177-184 ; 09608524 (ISSN) Hosseinzadeh, M ; Bidhendi, G. N ; Torabian, A ; Mehrdadi, N ; Pourabdullah, M ; Sharif University of Technology
    Abstract
    This paper introduces a new hybrid electro membrane bioreactor (HEMBR) for reverse osmosis (RO) pretreatment and advanced treatment of effluent by simultaneously integrating electrical coagulation (EC) with a membrane bioreactor (MBR) and its performance was compared with conventional MBR. Experimental results and their statistical analysis showed removal efficiency for suspended solids (SS) of almost 100% for both reactors. HEMBR removal of chemical oxygen demand (COD) improved by 4% and membrane fouling was alleviated according to transmembrane pressure (TMP). The average silt density index (SDI) of HEMBR permeate samples was slightly better indicating less RO membrane fouling. Moreover,... 

    Discovery of a tetracyclic indole alkaloid that postpones fibrillation of hen egg white lysozyme protein

    , Article International Journal of Biological Macromolecules ; Volume 183 , 2021 , Pages 1939-1947 ; 01418130 (ISSN) Ashrafian, H ; Zadeh, E.H ; Tajbakhsh, M ; Majid, N ; Srivastava, G.N ; Khan, R.H ; Sharif University of Technology
    Elsevier B.V  2021
    Abstract
    Protein aggregation, such as amyloid fibril formation, is molecular hallmark of many neurodegenerative disorders including Alzheimer's, Parkinson's, and Prion disease. Indole alkaloids are well-known as the compounds having the ability to inhibit protein fibrillation. In this study, we experimentally and computationally have investigated the anti-amyloid property of a derivative of a synthesized tetracyclic indole alkaloid (TCIA), possessing capable functional groups. The fibrillation reaction of Hen White Egg Lysozyme (HEWL) was performed in absence and presence of the indole alkaloid. For quantitative analysis, we used Thioflovin T binding assay which showed ~50% reduction in fibril... 

    Size-dependent genotoxicity of graphene nanoplatelets in human stem cells

    , Article Biomaterials ; Volume 33, Issue 32 , 2012 , Pages 8017-8025 ; 01429612 (ISSN) Akhavan, O ; Ghaderi, E ; Akhavan, A ; Sharif University of Technology
    2012
    Abstract
    Reduced graphene oxide nanoplatelets (rGONPs) were synthesized by sonication of covalently PEGylated GO sheets followed by a chemical reduction using hydrazine and bovine serum albumin. Human mesenchymal stem cells (hMSCs), as a fundamental factor in tissue engineering, were isolated from umbilical cord blood (as a recently proposed source for extracting fresh hMSCs) to investigate, for the first time, the size-dependent cyto- and geno-toxic effects of the rGONPs on the cells. The cell viability test showed significant cell destructions by 1.0 μg/mL rGONPs with average lateral dimensions (ALDs) of 11±4 nm, while the rGO sheets with ALDs of 3.8±0.4 μm could exhibit a significant cytotoxic...