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Symmetric and asymmetric bimanual coordination and freezing of gait in Parkinsonian patients in drug phases
, Article Annals of the New York Academy of Sciences ; Volume 1511, Issue 1 , 2022 , Pages 244-261 ; 00778923 (ISSN) ; Azad, A ; Akbarfahimi, M ; Behzadipour, S ; Taghizadeh, G ; Sharif University of Technology
John Wiley and Sons Inc
2022
Abstract
Freezing of gait (FOG) is a debilitating symptom in patients with Parkinson's disease (PD), which may be associated with motor control impairments in tasks other than gait. This study aimed to examine whether symmetric and asymmetric bimanual coordination is impaired in PD with FOG (PD +FOG) patients and whether dual-task and drug phases may affect bimanual coordination in these patients. Twenty PD +FOG patients, 20 PD patients without FOG (PD –FOG) performed symmetric and asymmetric functional bimanual tasks (reach to and pick up a box and open a drawer to press a pushbutton inside it, respectively) under single-task and dual-task conditions. PD patients were evaluated during on- and...