Sharif Digital Repository

A novel, magnetic nanocarrier was successfully synthesized through a facile and economical producer in which Fe3O4 magnetic nanoparticles were coated by starch-g-poly (methyl methacrylate-co-PEG-acrylamide). The surface of nanocarrier was then modified by hydrazine to preparation of a pH-responsive carrier. The resulted nanocarrier was applied for delivery of doxorubicin (DOX) as an effective anti-cancer drug. DOX was reacted with hydrazine linkage on the surface of nanocarrier to form hydrazone bond. Due to the presence of numerous hydrazine groups on the surface of magnetic nanocarrier large amounts of DOX was loaded onto the carrier (327 mg g−1). © 2016 The Korean Society of Industrial... 

A novel heterogeneous catalyst has been synthesized based on the distillation-precipitation-polymerization of methyl acrylate onto modified magnetic nanoparticles followed by the amidation of the methyl ester groups using N,N-dimethylethylenediamine. The resulting poly(dimethylaminoethyl acrylamide) coated magnetic nanoparticles (MNP@PDMA) catalyst was characterized using an array of sophisticated analytical techniques, including FT-IR, TGA, SEM, TEM, CHN, vibrating sample magnetometer (VSM), and XRD analysis. The resulting heterogeneous base catalyst allowed the performance of a domino Knoevenagel condensation/Michael addition/cycloaddition reaction toward the synthesis of... 

Anchoring of copper sulfate in layered poly(imidazole-imidazolium) coated magnetic nanoparticles provided a highly stable, active, reusable, high loading, and green catalyst for the click synthesis of 1,2,3-triazoles via a one-pot cycloaddition of alkyl halide, azide, and alkyne (Cu-A3C). The catalyst was characterized by FTIR, TGA, TEM, SEM, XRD, EDAX, VSM and AAS. High selectivity, broad diversity of alkyl/benzyl bromide/chloride and alkyl/aryl terminal alkynes, and good to excellent yields of products were obtained using 0.7 mol% catalyst. The catalyst was readily recovered and reused up to 6 times without significant loss of activity  

A heterogeneous magnetic copper catalyst was prepared via anchoring of copper sulfate onto multi-layered poly(2-dimethylaminoethyl acrylamide)-coated magnetic nanoparticles and was characterized using various techniques. The catalyst was found to be active, effective and selective for one-pot three-component reaction of alkyl halide, sodium azide and alkyne, known as copper-catalyzed click synthesis of 1,2,3-triazoles. As little as 0.3 mol% of catalyst was found to be effective under the optimum conditions. The catalyst could also be recycled and reused up to seven times without significant loss of activity. Thermal stability, high loading level of copper on catalyst, broad diversity of... 

A magnetic nanocomposite was prepared by entrapment of Fe3O4 nanoparticles into the cross-linked ionic liquid/epoxy type polymer. The resulting support was used for covalent immobilization of cellulase through the reaction with epoxy groups. The ionic surface of the support improved the adsorption of enzyme, and a large amount of enzyme (106.1 mg/g) was loaded onto the support surface. The effect of the presence of ionic monomer and covalent binding of enzyme was also investigated. The structure of support was characterized by various instruments such as FT-IR, TGA, VSM, XRD, TEM, SEM, and DLS. The activity and stability of immobilized cellulase were investigated in the prepared support. The... 

A heterogeneous tungstate-based catalyst has been prepared for selective oxidation of sulfides to sulfoxides in the presence of 30% H2O2. The catalyst was prepared via immobilization of high amounts of WO4 2− onto the cross-linked poly(ammonium ethyl acrylamide) coated magnetic nanoparticles (MNP). FT-IR, TEM, TGA, VSM, XRD, EDX, and CHN analysis were used for characterization of catalyst. Variety of sulfides successfully converted to the related sulfoxides using 1 mol% of catalyst at room temperature in high yields. The catalyst was easily recovered and reused up to 6 times without loss of activity  

A novel bi-functional polymeric catalyst was synthesized by immobilization of tungstate anions onto the nitrogen rich poly(ionic liquid)/magnetic nanocomposite. The resulting catalyst has two types of catalytic sites: (i) immobilized WO4 anions with bis-imidazolium ionic liquid cation for selective oxidation of alcohols and (ii) basic amine groups for Knoevenagel condensation between produced aldehyde and malononitrile. Due to the polymeric nature of the catalyst, large amounts of tungstate and basic nitrogen groups were presented on the solid surface which led to a decrease in the applied catalyst mass for catalytic reaction. High catalytic activity and excellent selectivity of catalyst in... 

In the bone tissue engineering field (BTE), it is of significant importance to develop bioactive multifunctional scaffolds with enhanced osteoconductivity, osteoinductivity, and antibacterial properties required for lost bone tissue regeneration. In this work, a bioactive glass-ceramic scaffold was manufactured via a novel polymer-derived ceramics (PDC) manufacturing method. To gain antibacterial properties, the silver ions were incorporated in controlled amount along with other precursors in the PDC processing stage. Microstructural and structural properties of the fabricated silicate-phosphate glass-ceramic scaffold were evaluated by scanning electron microscopy (SEM) equipped with energy... 

In the bone tissue engineering field (BTE), it is of significant importance to develop bioactive multifunctional scaffolds with enhanced osteoconductivity, osteoinductivity, and antibacterial properties required for lost bone tissue regeneration. In this work, a bioactive glass-ceramic scaffold was manufactured via a novel polymer-derived ceramics (PDC) manufacturing method. To gain antibacterial properties, the silver ions were incorporated in controlled amount along with other precursors in the PDC processing stage. Microstructural and structural properties of the fabricated silicate-phosphate glass-ceramic scaffold were evaluated by scanning electron microscopy (SEM) equipped with energy... 

Let R be a ring and f(x1,..., xn) be a polynomial in noncommutative indeterminates x1,..., xn with coefficients from ℤ and zero constant. The ring R is said to be an f-ring if f(r1,..., rn) = 0 for all r1,..., rn of R and a virtually f-ring if for every n infinite subsets X1,..., Xn (not necessarily distinct) of R, there exist n elements r1 ∈ X1,...,rn ∈ Xn such that f(r1,..., rn) = 0. Let R* be the 'smallest' ring (in some sense) with identity containing R such that Char (R) = Char (R*). Then denote by ZR the subring generated by the identity of R* and denote by f̄R the image of f in ZR [x1,..., xn] (the ring of polynomials with coefficients in ZR in commutative indeterminates x1,..., xn)....