Sharif Digital Repository

This review highlights using nanotechnology in increasing the bioavailability of AP (Apigenin) to enhance its therapeutic efficacy in breast cancer treatment. Breast cancer is one of the most leading causes of cancer death in women both in developed and developing countries. According to several epidemiological and clinical trial studies that indicate progestin-stimulated breast cancer in post-menopausal women; it is necessary to determine compounds to suppress or attenuate the tumor-promoting effects of progestins in breast cells. For this purpose, using the natural anti-progestins, including AP compared with the chemical ones could be significantly effective due to the lack of toxicities... 

Ground improvement techniques are inevitable for weak soils that cannot endure the design load imposed by superstructures. Deep mixing technique (DMT) as one of these methods is promising and effective when a deep soil layer with low bearing capacity is encountered. Such deposits are quite common in the South-west of Iran where the studied site is located. In order to validate the influence of DMT on the enhancement of strength, both in-situ and laboratory tests were conducted. Afterwards, a parametric study was carried out to investigate the influence of key factors including cement content, water–cement ratio, curing time and plasticity index (PI) on the performance of DMT. In summary, a... 

Recently, smart water (SmW) and nanocomposite (NC) flooding have shown good potential for enhanced oil recovery (EOR) processes. Although SmW and NCs are found to influence the oil recovery, there are still some controversies regarding their performance on wettability alteration (WA). To address this important question, we synthesized new NC materials with high hydrophilic properties. In this research, in the first stage, a NC was synthesized. The obtained compound was known as (UiO-66-NH2/TiO2/ZnO) (UNTZ). For the identification of NC, scanning electron microscopy (SEM), Brunauer–Emmett–Teller (BET), Fourier transform infrared spectroscopy (FTIR), and X-ray Diffraction (XRD) techniques were... 

In the present study, a one step hydrothermal process was employed to synthesize magnetite nanoparticles using oleic acid as surfactant agent at 140 °C. Effects of reaction time and alkalinity were studied on particles size and morphology. By changing these parameters, some monodisperse spherical nanoparticles with mean particle size between 2.71 and 13.88 nm were synthesized and characterized via TEM, XRD, VSM, TGA and FT-IR techniques. Assuming the Avrami behavior of particles formation, a kinetics equation was proposed for the transformation rate at 140 °C. Using some simplifying assumptions, nucleation and growth rates were calculated for the hydrothermal formation of magnetite... 

Ground improvement techniques are inevitable for weak soils that cannot endure the design load imposed by superstructures. Deep mixing technique (DMT) as one of these methods is promising and effective when a deep soil layer with low bearing capacity is encountered. Such deposits are quite common in the South-west of Iran where the studied site is located. In order to validate the influence of DMT on the enhancement of strength, both in-situ and laboratory tests were conducted. Afterwards, a parametric study was carried out to investigate the influence of key factors including cement content, water–cement ratio, curing time and plasticity index (PI) on the performance of DMT. In summary, a... 

Ground improvement techniques are inevitable for weak soils that cannot endure the design load imposed by superstructures. Deep mixing technique (DMT) as one of these methods is promising and effective when a deep soil layer with low bearing capacity is encountered. Such deposits are quite common in the South-west of Iran where the studied site is located. In order to validate the influence of DMT on the enhancement of strength, both in-situ and laboratory tests were conducted. Afterwards, a parametric study was carried out to investigate the influence of key factors including cement content, water–cement ratio, curing time and plasticity index (PI) on the performance of DMT. In summary, a... 

In this article, the buckling behavior of a nanoplate at the bottom of the channel over which the fluid passes with a one-dimensional flow was investigated. Navier–Stokes equations were used to obtain the applied force from the fluid to the nanoplate. Nonlocal elasticity theory was used to consider nanoscale effects, and this problem was solved using Galerkin’s weighted residual method. In previous research, the buckling behavior of nanoplates was done with the assumption of buckling in a vacuum, but in this study, the environment around the nanoplate is assumed to be a flowing viscous fluid. According to the results presented in this study, the critical buckling load of nanoplates coupled... 

In this study, Glucoamylase production by Aspergillus niger was investigated under solid state fermentation using low cost by-products of agricultural processes as substrate. Highest enzyme production was observed when a combination of wheat bran (WB) and corn flour (CF) was used as compared to WB+ rice bran, WB+ rice flour and WB alone. Several compositions of corn flours were experimented. The best combination of WB in addition of 10% corn flour resulted maximum enzyme activities. Study of the fermentations in flasks revealed 373.3 IU/gds and 41.4 g/l for the enzyme activity and protein concentration respectively under conditions of 30± 1°C, pH 4.7 and time 96 h. Optimum conditions... 

Superparamganetic iron oxide-based contrast agents in magnetic resonance imaging (MRI) have offered new possibility for early detection of lymph nodes and their metastases. According to important role of nanoparticle size in biodistribution, magnetite nanoparticles coated with different polyethylene glycol (PEG) concentrations up to 10/1 PEG/iron oxide weight ratio in an ex situ manner. To predict the PEG-coated nanoparticle behavior in biological media, such as blood stream or tissue, colloidal stability evaluation was performed to estimate the coating endurance in different conditions. Accordingly, optical absorbance measurements were conducted in solutions with different values of pH and... 

The solubility of hydrogen sulphide in three ionic liquids, viz. 1-hexyl-3-methylilmidazolium hexafluorophosphate ([hmim][PF6]), 1-hexyl-3-methylimidazolium tetrafluoroborate ([hmim][BF4]), and 1-hexyl-3-methylimidazolium bis(trifluoromethanesulfonyl)imide ([hmim][Tf2N]), at temperatures ranging from 303.15 K to 343.15 K and pressures up to 1.1 MPa were determined. The solubility values were correlated using the Krichevsky-Kasarnovsky equation and Henry's constants were obtained at different temperatures. Partial molar thermodynamic functions of solvation such as standard Gibbs free energy, enthalpy, and entropy were calculated from the solubility results. Comparison of the values obtained... 

The solubility of hydrogen sulfide in three ionic liquids, 1-butyl-3-methylimidazolium hexafluorophosphate ([bmim][PF6]), 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim][BF4]), and 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide ([bmim][Tf 2N]), at temperatures ranging from (303.15 to 343.15) K and pressures up to 1 MPa was determined. The solubility data were correlated using the Krichevsky-Kasarnovsky equation, and Henry's law constants at different temperatures were obtained. From the solubility data, the partial molar thermodynamic functions of solution such as Gibbs energy, enthalpy, and entropy were calculated. Comparison showed that the solubility of H2S in these... 

Considering the lipid concentration and side effects regarding the stents used by surgeons, a new heart stent model is proposed. In the new stent, a few piezo plates are designed and attached to the stents by which release of the lipids can take place due to the applied alternative voltages. Due to the vibrations of small-scale piezoelectric plates, the deposition of low-density-lipoproteins (LDL) floating in the blood flow in the coronary arteries is prevented. Small-scale effects are considered using nonlocal elasticity theory, and the interaction between fluid and solid is modeled using the Navier-Stokes equation. The effect of fluid parameters as well as applied voltage and geometry...