Sharif Digital Repository

Cancer is one of the main causes of death among all people around the world. This shows that more and more attention should be paid to cure cancer. One of the most common cancer treatments is radiation therapy. Among all radiation therapy treatments, Intensity-Modulated Radiation Therapy is a very effective and flexible ways to treat cancer. There are numerous mathematical problems to find the perfect treatment plan. One of these mathematical problems is Fluence Map Optimization in which we try to find the best dose intensity for each tumor and surrounding organs. The main purpose in this problem is to minimize the number of cancerous cells which are being destroyed while minimizing the... 

This thesis aims to assess the seismic risk of the community of schools with masonry buildings in the Tehran metropolitan in the next 50 years and to prioritize the buildings of this community for seismic retrofit based on the optimal mitigation of risk of the community. Tehran is among the largest cities with the highest level of seismic risk in the world, and Masonry buildings are among the structures with poor seismic performance; Therefore, it is essential to conduct a comprehensive and accurate evaluation of the seismic risk of schools, as one of the most critical and sensitive occupancies, in this region and with this type of structure. It is also very beneficial to reduce the seismic... 

Based on the importance of DNA/RNA binding proteins in different cellular processes, finding binding sites of them play crucial role in many applications, like designing drug/vaccine, designing protein, and cancer control. Many studies target this issue and try to improve the prediction accuracy with three strategies: complex neural-network structures, various types of inputs, and ML methods to extract input features. But due to the growing volume of sequences, these methods face serious processing challenges. So, this paper presents KDeep, based on CNN-LSTM and the primary form of DNA/RNA sequences as input. As the key feature improving the prediction accuracy, we propose a new encoding... 

In this thesis, we review recent advances on controlling of complex systems. We provide in details, the concepts of synchronizability and synchronization controllability.Then we will investigate synchronization controllability under different pinning schemes, and propose a new pinning strategy to increase controllability and consequently decrease the number of required pinned nodes (known as driver nodes) to assure a stable synchronized state. We also study the network characteristics of resulted sequence of driver nodes. Finally, we will employ our proposed schemes to study the controllability of complex networks of chaotic Rossler oscillators  

Speech synthesis and its applications have been very attractive recently. The main purpose of this technique is to produce a speech signal with natural characteristics of human speech like prosody and emotion. Among all existing methods for speech synthesis, statistical parametric speech synthesis methods are more promising because ofhigher flexibility in comparison to other methods. One of the applications of speech synthesis is speech to speech translation. In these systems, the generated voice in target language should have the same characteristics as the input voice in source language. The main purpose of this research is to review and evaluate the cross lingual speaker adaptation... 

Surface piercing propellers are particular type of supercavitating propellers that are commonly used for High-speed vessels. Most studies on this type of propellers has been investigating the hydrodynamic forces. But in recent years with increase in SPPs diameter used in vessels, structural analysis of this type of propellers is considered. For this purpose, studies on the stresses exerted on the propeller structures under load is done with the help of Hydro elastic methods. In this type of analysis, structura of propeller is intended to be flexible and Displacements under pressure checked and Tensions resulting from it are studied.
The present Thesis using ANSYS software to analyze a... 

Pricing plays an important and essential role in the profit and income of companies. The importance of pricing is not only related to its role in the company's profitability, but it also changes the customer's understanding and loyalty towards the company and can create the company's reputation or destroy it. Determining the right price will increase product sales and increase customer loyalty and create a competitive advantage for the company. One of the most important and influential variables in product pricing is the amount of demand. The main challenge of companies for product pricing is the uncertainty in their demand. In order to deal with this problem, data-driven pricing is used.... 

The increasing demand for autonomous vehicles and reliable communication protocols and hardware interfaces, such as CAN bus and USB, underscores the necessity for stable clock sources that maintain a low temperature coefficient (TC) over wide temperature ranges. This demand is particularly emphasized in applications such as wearables, network sensors, downhole devices, WSNs, and IoT, where long-lasting battery life and frequency-stable clock sources over a broad temperature range (e.g. -20 °C to 100 °C) are crucial. Traditionally, variations in frequency caused by temperature have been mitigated by employing off-chip components like crystals or ceramic based oscillators, but this approach... 

The main concept of this thesis is to simulate, develop, and analyze the performance of force control method by applying to a Unimate MK-II hydraulic manipulator. In this investigation, simulation studies are based on the concept of impedance control technique. Position-based formulation of impedance control is employed. First in this research, a PID controller is employed and is shown to be capable of performing position control task precisely despite the fact that inertia, joint stiction, valve deadband and other nonlinearities are presented. Although trajectory tracking is performed well after several investigations, we have concluded that the impedance control cannot perform a desirable... 

Autonomous vehicles, as an integral part of intelligent transportation systems, will play a significant role in the future of transportation services. These vehicles have a high potential to improve road traffic capacity and the efficiency of transportation systems. One type of autonomous vehicle is the connected and autonomous vehicle (CAV), which can communicate with each other, roadside units, traffic control signals, and other infrastructures or devices. This study investigates the impact of autonomous vehicles and connected and autonomous vehicles on the traffic flow of the Tehran-Karaj freeway and vice versa, under various penetration rates and in a mixed traffic environment. In this... 

In the current situation and considering the economic conditions, entrepreneurship and self-employment are important factors of business growth. To prepare people in this field, there is a need for effective training that can motivate people. Identifying the effective methods and different dimensions of the entrepreneurship education framework that can lead to setting up a successful program for training people and facilitate the way to achieve the goal of education is one of the important goals of this research. By studying the literature from 2010 onwards, this research systematically examined 96 articles and tried to improve the framework of entrepreneurship education that was stated in... 

Research on the characteristics of the near field earthquakes has been very popular in recent years due to the considerable damages they have caused to the structures located within the vicinity of seismic sources. The incapability of response spectra for structural damage assessment has been revealed through recent investigations. The recorded data show that the near field earthquakes are often accompanied by a large energy pulse in the beginning of the records caused by the so-called directivity phenomenon. That has encouraged many researchers to study the possibility of using the velocity pulse of these records to evaluate the imposed seismic demands on structures. Thus, investigating the...