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    Simulation of Flow's Effect on Microfluid Through 3-Dimentional Scaffold in a Bioreactor

    , M.Sc. Thesis Sharif University of Technology Seddiqi, Hadi (Author) ; Bastani, Dariush (Supervisor) ; Amoabediny, Ghassem (Supervisor)
    Abstract
    Tissue engineering aims to produce artificial tissues and organs to treat the damaged part, by implant in body of patients, is an important issue in research and development. In cases that tissue damage is sever or due to genetic defects or congenital disease, tissue in the body are not fully formed, tissue engineering can be used to regenerate, repair or replace organs or tissues. Cell culture on the scaffold and put it in the bioreactor is a critical step in the formation of tissues or organs. Among various bioreactors, perfusion bioreactor due to increase of convection in the structure of cell-scaffold is widely used. Enhancement of convection increases shear stress on the cells that is... 

    Investigating the effect of design parameters on the response time of a highly sensitive microbial hydrogen sulfide biosensor based on oxygen consumption

    , Article Biosensors and Bioelectronics ; Volume 70 , 2015 , Pages 106-114 ; 09565663 (ISSN) Vosoughi, A ; Yazdian, F ; Amoabediny, G ; Hakim, M ; Sharif University of Technology
    Elsevier Ltd  2015
    Abstract
    A novel hydrogen sulfide microbial biosensor was developed based on investigating the influence of four design parameters: cell concentration, immobilization bed type, hydrogen sulfide concentration, and geometrical shape of the biosensor. Thiobacillus thioparus was used as the recognition element and it was immobilized on sodium alginate as well as agarose bed. The results were optimized by the application of statistical optimization software based on response time of the system. Oxygen reduction was considered as the detection sign. Sodium alginate solution with a concentration of 2.3% (w/v) and optical density of 10 at 605. nm was found as the optimum conditions for immobilization with... 

    Soft Error & Crosstalk Fault Mitigation in Network-On-Chips

    , Ph.D. Dissertation Sharif University of Technology Patooghy, Ahmad (Author) ; Miremadi, Ghassem (Supervisor)
    Abstract
    Recent advances in VLSI technologies have enabled current silicon dies to accommodate billions of transistors in the design of very complex System-on-Chips (SoCs). To address the resulting complexity, Network-on-Chips (NoCs) have emerged as a paradigm to design scalable communication architecture to connect the processing cores of an SoC. However, smaller feature sizes, lower voltage levels and higher frequencies in Deep Sub-Micron (DSM) technologies make NoCs highly susceptible to transient faults, e.g., crosstalks, particle strikes, electro-magnetic interferences, and power supply disturbances. Single Event Upsets (SEUs) caused by high energy particle strikes as well as crosstalks are the... 

    Improving Fault Tolerance in Safety-Critical Distributed Automotive Communication Networks

    , Ph.D. Dissertation Sharif University of Technology Sedaghat, Yasser (Author) ; Miremadi, Ghassem (Supervisor)
    Abstract
    Nowadays, distributed embedded systems are extensively employed in safety-critical automotive applications, e.g. Steer-By-Wire and Brake-By-Wire. Moreover, according to the present and future needs of the automotive industry of Iran, in this Ph.D. thesis, fault tolerance in safety-critical distributed automotive communication networks has been improved. This thesis consists of three research layers. In the first layer, several comprehensive studies on all automotive communication protocols and their architectures have been done. Among the protocols, the FlexRay communication protocol has been selected to employ in safety-critical distributed embedded systems. In the second layer, the fault... 

    Including Facilities in an Embedded Processor for External Watchdog Processors

    , M.Sc. Thesis Sharif University of Technology Khosravi, Faramarz (Author) ; Miremadi, Ghassem (Supervisor)
    Abstract
    The wide range of embedded processors and their reliance on nano-scale technologyhave brought them serious concerns on reliability, power consumption, timeliness and cost. Therefore, theseconcernsmust be addressed at the design process withemploying minimum facilities.This thesis proposes a low-cost concurrent error detection method based on control flow checking suitable for embedded processors. Most of the previous control flow checking methods either do not consider the embedded processors concerns, or they are not applicable to processors with on-chip cache memories.The key idea behind the proposed control flow checking method is to embed specific hardware components in the IP core of an... 

    Design and Implementation of Fault-Tolerance Mechanisms for Scratch-Pad Memories (SPM) in Embedded Processors

    , M.Sc. Thesis Sharif University of Technology Farbeh, Hamed (Author) ; Miremadi, Ghassem (Supervisor)
    Abstract
    Energy consumption, area, reliability and predictability are the major concerns in embedded systems. Using scratchpad memories (SPMs) instead of cache memories has an increasing role to satisfy these limitations. SPM as an on-chip SRAM memory is highly vulnerable to soft errors and as it contains the most frequently used blocks of the program, errors in SPM can easily propagate in system leading to erroneous results. This thesis proposes two approaches to protect the SPM against soft errors. The first approach, MM-SPM, proposed to protect the instruction SPM and the second approach, CR-SPM, proposed to protect dynamically mapped data and instructions to the SPM. The main idea behind the... 

    Transient Fault Detection in Embedded Processors using Built In Self-Test (BIST) Facilities

    , M.Sc. Thesis Sharif University of Technology Ebrahimi, Mohammad (Author) ; Miremadi, Ghassem (Supervisor)
    Abstract
    Ever increasing applications of embedded systems have motivated designers to pay special atten-tion to the design requirements of such systems. Among embedded applications, safety-critical sys-tems have high reliability requirements as failures in such systems may endanger human life or re-sult in catastrophic consequences. Embedded processors as the computation cores of embedded systems are very crucial from reliability point of view. Reducing feature size, power supply voltage and also increasing operating frequency have increased the occurance rate of transient faults in such processors. Built in Self-Test facilities available in many of embedded systems forms about 70% of total cost in... 

    Design and Implementation of Resource Allocation Mechanisms in Fault-tolerant Distributed Real-time Systems

    , M.Sc. Thesis Sharif University of Technology Nabavi, Sahebeh (Author) ; Miremadi, Ghassem (Supervisor)
    Abstract
    One of the most important characteristics of real-time systems is executing tasks before their specified deadlines. The tasks’ execution may require several resources like processor, I/O ports, and data structures. Some of these resources may be shared between several tasks and their availability is important in executing tasks before the deadlines. Allocating shared resources which are used in mutually exclusive manner often encounteres some problems such as priority inversion and deadlock. Resource access protocols are used to minimize or eliminate these problems. The effect of using these protocols issupporting tasks’ execution before their deadlines. To meet deadlines is of decisive... 

    Design and Evaluation of a Reliable Switching Method for Network-on-Chips

    , M.Sc. Thesis Sharif University of Technology Allivand, Yassin (Author) ; Miremadi, Ghassem (Supervisor)
    Abstract
    Growth in the number of transistors on a single die has made Network-on-Chips more vulnerable to transient faults such as Crosstalks, SEUs and MBUs. The aim of this thesis is to evaluate the effects of virtual channel structures on the performance and the power consumptions of NoCs in the presence of transient faults. Evaluations have been carried out by different switch architectures and experimental conditions, i.e., different traffic and fault injection rates. In this regard, we have measured the power and latency of the switch both in different buffer allocation mechanisms and different switching methods. The evaluated switching methods in this work vary from Virtual Cut through (VCT) to... 

    A Recomputation-based Algorithm for Error Correction in Scratchpad Memory

    , M.Sc. Thesis Sharif University of Technology Sayadi, Hossein (Author) ; Miremadi, Ghassem (Supervisor)
    Abstract
    Scratchpad memory (SPM) is extensively used as the on-chip memory in modern embedded processors alongside of the cache memory or as its alternative. Soft errors in SPM are one of the major contributors to system failures, due to ever-increasing susceptibility of SPM cells to energetic particle strikes. Since a large fraction of soft errors occurs in the shape of Multiple-Bit Upsets (MBUs), traditional memory protection techniques, i.e., Error Correcting Code (ECCs), are not affordable for SPM protection; mainly because of their limited error coverage and/or their high overheads. This thesis proposes a novel recomputation-based algorithm that efficiently protects SPM with high error... 

    Analysis of Software-based Techniques for Detecting Soft Errors in Embedded Systems

    , M.Sc. Thesis Sharif University of Technology Ghasemi, Golsa (Author) ; Miremadi, Ghassem (Supervisor)
    Abstract
    The development of embedded systems in safety critical applications leads to using fault tolerant methods to improve their dependability. Among the various fault tolerant methods, recently, software based methods are more appealing during to the following reasons: 1) They are applicable to the Commercial-Off-The Shelf (COTS) processors and lead to reduction in cost and time to market, 2) Unlike the traditional hardware based internal error detection methods, software based methods fault coverage are more promising, and 3)Software-based methods are cheaper, quicker and do not require any hardware modifications. The technology scaling trend in recent years, made system more vulnerable to... 

    Reliability Enhancement of Cache Memories Based on Non-Volatile Cells

    , M.Sc. Thesis Sharif University of Technology Ghaemi, Golsana (Author) ; Miremadi, Ghassem (Supervisor)
    Abstract
    Nowadays, leakage energy constitutes up to 80% of total cache energy consumption and tag array is responsible for a considerable fraction of static energy consumption. An approach to reduce static energy consumption is to replace SRAMs by STT-RAMs with near zero leakage power. However, a problem of an STT-RAM cell is its limited write endurance. In spite of previous studies which have targeted the data array, in this study STT-RAMs are used in the L1 tag array. To solve the write endurance problem, this study proposes an STT-RAM/SRAM tag architecture. Considering the spatial locality of memory references, the lower significant bit-lines of the tag update more. The SRAM part handles the... 

    Fault Tolerance in Cloud Storage Systems Using Erasure Codes

    , M.Sc. Thesis Sharif University of Technology Safaei, Bardia (Author) ; Miremadi, Ghassem (Supervisor)
    Abstract
    International Data Company (IDC) has reported, at the end of 2020, the total amount of digital data stored in the entire world will reach 40 thousand Exabytes. The idea of accessing this volume of data, anywhere at any time by exploiting commodity hardware, led into the introduction of cloud storage. The abounded rate and variety of failures in the equipment used in cloud storage systems, placed fault tolerance, at top of the challenges in these systems. HDFS layer in Hadoop has provided cloud with reliable storage. Replication is the conventional method to protect data against failures in HDFS. But the storage overhead is a big deal and therefore designers are tending towards erasure codes.... 

    Offering Aging Mitigation Technique for SRAM based on Chip Memories

    , M.Sc. Thesis Sharif University of Technology Karimi, Maryam (Author) ; Miremadi, Ghassem (Supervisor)
    Abstract
    Bias Temperature Instability (BTI) is known as one serious reliability concern in nanoscale technology sizes. BTI gradually degrades threshold voltage (Vth) of MOS transistors. The main consequence of Vth degradation in SRAM cell transistors is the Static Noise Margin (SNM) degradation that makes SRAM cells susceptible against soft errors. SNM degradation in SRAM cells results in bit-flip occurrences and should be monitored accurately before resulting in permanent failures. This work proposes a sensor called Current-based BTI Sensor (CBS) to assess the aging state of SRAM cells. CBS measures BTI-induced SNM degradation of SRAM cells by monitoring the write current shifts due to BTI. The... 

    Improving the Reliability of the STT-RAM Caches Against Transient Faults

    , M.Sc. Thesis Sharif University of Technology Azad, Zahra (Author) ; Miremadi, Ghassem (Supervisor)
    Abstract
    Cache memories occupy a large portion of processors chip area. According to academic and industrial reports, the dominant effect of leakage current in less than 40-nm technology nodes has led to serious challenges in scalability and energy consumption of SRAM and DRAM memories. To overcome this challenge, different types of non-volatile memories have been introduced. Among them, Spin-Transfer Torque Random Access Memory (STT-RAM) memory is known as the best candidate to replace SRAM in the cache memories, due to its high density and low access latency. Despite their advantages over SRAMs, several problems in STT-RAM need to be addressed to make it applicable in cache memories. The most... 

    Reliability Improvement of Non-Volatile Cache Memories Against Wearout

    , M.Sc. Thesis Sharif University of Technology Asadi, Sina (Author) ; Miremadi, Ghassem (Supervisor)
    Abstract
    In recent years we have witnessed a growth in handheld or wearable technologies among others, which have tested the limits of SRAM. The technological advancements of recent years and a persistent trend in reduced feature sizes have been testing the limits of SRAM for quite a while. It is becoming clear that because of high leakage the SRAM technology does not satisfy the ever increasing demand for reduced cost and dimensions, and, as a result Non-Volatile Memory with lower leakage property is a promising alternative to bridge the aforementioned gaps. But limited endurance is one of its weaknesses.In this paper we propose a novel method dubbed “online write-prevention coding” to incorporate... 

    Fabrication and characterization of electrospun poly-L-lactide/gelatin graded tubular scaffolds: Toward a new design for performance enhancement in vascular tissue engineering

    , Article Progress in Natural Science: Materials International ; Volume 25, Issue 5 , October , 2015 , Pages 405–413 ; 10020071 (ISSN) Yazdanpanah, A ; Tahmasbi, M ; Amoabediny, G ; Nourmohammadi, J ; Moztarzadeh, F ; Mozafari, M ; Sharif University of Technology
    Elsevier  2015
    Abstract
    In this study, a new design of graded tubular scaffolds have been developed for the performance enhancement in vascular tissue engineering. The graded poly-L-lactide (PLLA) and gelatin fibrous scaffolds produced by electrospining were then characterized. The morphology, degradability, porosity, pore size and mechanical properties of four tubular scaffolds (graded PLLA/gelatin, layered PLLA/gelatin, PLLA and gelatin scaffolds) have been investigated. The tensile tests demonstrated that the mechanical strength and also the estimated burst pressure of the graded scaffolds were significantly increased in comparison with the layered and gelatin scaffolds. This new design, resulting in an increase... 

    Investigation of the Effects of Aging and Process Variation on Reliability in SRAM Based Memory Circuits

    , M.Sc. Thesis Sharif University of Technology Nazari, Reza (Author) ; Miremadi, Ghassem (Supervisor)
    Abstract
    Negative Bias Temperature Instability (NBTI) in CMOS devices is known as the major source of aging effect leading to performance and reliability degradation in modern processors. Instruction-cache (I-cache), which has a decisive role in performance and reliability of the processor, is one of the most affected modules by NBTI. Variations in duty Cycles and long-time residency of data blocks in I-cache lines (stress condition) are the two major causes of NBTI acceleration. This paper proposes a novel I-cache management technique to minimize the aging effect in the I-cache SRAM cells. The proposed technique consists of a smart controller that monitors the cache lines behavior and distributes... 

    Reliability Analysis of Energy Harvesting Wireless Sensor Networks

    , M.Sc. Thesis Sharif University of Technology Mirbaha, Elaheh (Author) ; Miremadi, Ghassem (Supervisor)
    Abstract
    Wireless Sensor Networks (WSN) are wildly utilized in surveillance and controling applications, and because of their remote and standalone operation, lifetime and reliability of a typical WSN are two main concerns in these networks. One of the reliability threatening issues in a WSN is residual accessible energy for each node. Nowadays, energy harvesting systems are used in WSN nodes to catch environmental energy, and reduce the energy limitation. However, because of inherent uncertainty of energy harvesting systems, the networks that operate using environmental energy have new reliability issues. Different rate of energy harvesting, according to environmental conditions, is one of the most... 

    Reliability Improvement in 3D Network-on-chips Against Crosstalk Fault

    , M.Sc. Thesis Sharif University of Technology Mirosanlou, Reza (Author) ; Miremadi, Ghassem (Supervisor)
    Abstract
    Technology node scaling in recent decades ushered in gate delay cut-off and rise of interconnection latency. Hence, interconnects have become a major performance bottleneck of high performance system-on-chips (SoC) and integrated circuits (IC). In addition, interconnectiosns have become more susceptible to noises in particular crosstalk. On the other hand, the advent of multi-core processors with ever increasing number of cores has highlighted the need for fast and reliable interconnections. One of the potential solutions to alleviate the interconnection delay problem is the three dimensional integration using through-silicon vias (TSV). Vertical integration of IC dies using TSVs offers high...