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    Design and Fabrication of a 3D Multiparticle Microfluidic System

    , M.Sc. Thesis Sharif University of Technology Olyanasab, Ali (Author) ; Fardmanesh, Mehdi (Supervisor) ; Annabestani, Mohsen (Co-Supervisor)
    Abstract
    Microfluidic technology is a field of science that deals with the design, implementation, optimization, and testing of fluid systems in small dimensions. This technology has made significant progress in various fields in the last decade, especially in medical engineering. As an interdisciplinary scientific field, this growing technology has many applications in medicine, pharmaceuticals, chemistry, and electronic industries. One of the primary applications of microfluidic devices is the development of "lab-on-a-chip" systems as point-of-care diagnostic tools, such as rapid diagnosis during surgery. A microfluidic system includes various functional modules: sample preparation and fluid... 

    Design and Optimization of an Intelligent Impedance-based Flow Cytometer for POCT Applications

    , M.Sc. Thesis Sharif University of Technology Meskar, Zahra (Author) ; Fardmanesh, Mehdi (Supervisor) ; Annabestani, Mohsen (Co-Supervisor)
    Abstract
    Microfluidics is the science of fabricating systems interfacing fluids of small volume and size ranging from microliters (10-6) to picolitres (10-12). Due to its remarkable features, such as low sample and reagent consumption, high sensitivity, low cost, automated devices, and short experimental time, microfluidic chips have been widely used as laboratory assays. As a term often used and described in “lab on a chip” and “organ on a chip” technologies, microfluidic chips have been used in the fast and frugal diagnosis of infectious diseases such as HIV, microscale surgery on single cells and tiny organisms and cell culture.The design, simulation, optimization, and fabrication of an... 

    Design and fabrication of an ubiquitous, low-cost, and wearable respiratory bio-sensor using ionic soft materials

    , Article 26th National and 4th International Iranian Conference on Biomedical Engineering, ICBME 2019, 27 November 2019 through 28 November 2019 ; 2019 , Pages 55-59 ; 9781728156637 (ISBN) Annabestani, M ; Mirzaei, I ; Esmaeili Dokht, P ; Fardmanesh, M
    Institute of Electrical and Electronics Engineers Inc  2019
    Abstract
    The respiratory system is a vital organ system which makes breathing and gas exchange possible for human's body. The loss of functionality in this system is due to either genetical problems or environmental issues like pollution or toxic gases which in many cases is inevitable. These circumstances may cause different respiratory diseases which may not be curable presently but their side effects can be partly controlled by careful and timely analysis improving the quality of patient's life. So, an appropriate device for conducting different analysis can be effective for people who suffer from respiratory diseases such as chronic obstructive pulmonary disease (COPD), asthma, occupational lung... 

    A new threshold selection method based on fuzzy expert systems for separating text from the background of document images

    , Article Iranian Journal of Science and Technology - Transactions of Electrical Engineering ; Volume 43 , 2019 , Pages 219-231 ; 22286179 (ISSN) Annabestani, M ; Saadatmand Tarzjan, M ; Sharif University of Technology
    Springer International Publishing  2019
    Abstract
    Threshold selection for text segmentation is an essential preprocessing step in most document processing algorithms. Although there are a number of sophisticatedly well-trained methods for text extraction, many researchers still prefer a fast and simple threshold selection algorithm for preprocessing. In this paper, a new global threshold selection method is proposed based on fuzzy expert systems (FESs). It initially enhances image contrast by using a FES. Then, the range of the threshold value is adjusted by using another FES and a pixel-counting algorithm. Finally, the threshold value is obtained as the middle value of the above range. To evaluate the performance of the proposed algorithm,... 

    Two‐qubit Quantum State Sharing

    , M.Sc. Thesis Sharif University of Technology Annabestani, Razieh (Author) ; Karimipour, Vahid (Supervisor)
    Abstract
    One of the problems that we are deal with in quantum information is secure transition of information. In Quantum State Sharing, we can encode our data on the quantum state and share the quantum state among some people such that none of the can be able to retrieve the state without collaboration with others. In this thesis, we will be concerned with reviewing of classical and quantum secret sharing and finally introduce another method in order to share a two qubit secret between N parties such any of the members can retrieve the state only with collaboration with other parties. It will be shown that using only Bell Pairs as recourse and measurement basis makes this model more efficient than... 

    A novel, low cost, and accessible method for rapid fabrication of the modifiable microfluidic devices

    , Article Scientific Reports ; Volume 10, Issue 1 , 2020 Annabestani, M ; Esmaeili Dokht, P ; Fardmanesh, M ; Sharif University of Technology
    Nature Research  2020
    Abstract
    As microfluidic chips are evolving to become a significant analysis tool toward POCT devices, it is crucial to make the cost and the time required for the fabrication process of these chips as low as possible. Because of the multidisciplinary nature of these systems and the collaboration of many different laboratories and organizations from vastly various fields with unequal types of equipment, it is essential to develop new techniques and materials to make the integration of disparate systems together more straightforward, accessible, and economical. In this paper, we present ethylene–vinyl acetate (EVA) as a new polymer-based material for the fabrication of different microfluidic chips,... 

    Fuzzy descriptive evaluation system: real, complete and fair evaluation of students

    , Article Soft Computing ; Volume 24, Issue 4 , 2020 , Pages 3025-3035 Annabestani, M ; Rowhanimanesh, A ; Mizani, A ; Rezaei, A ; Sharif University of Technology
    Springer  2020
    Abstract
    In recent years, descriptive evaluation has been introduced as a new model for educational evaluation of Iranian students. The current descriptive evaluation method is based on four-valued logic. Assessing all students with only four values is led to a lack of relative justice and creation of unrealistic equality. Also, the complexity of the evaluation process in the current method increases teacher error’s likelihood. As a suitable solution, in this paper, a fuzzy descriptive evaluation system has been proposed. The proposed method is based on fuzzy logic, which is an infinite-valued logic, and it can perform approximate reasoning on natural language propositions. By the proposed fuzzy... 

    Active microfluidic micromixer design using ionic polymer-metal composites

    , Article 27th Iranian Conference on Electrical Engineering, ICEE 2019, 30 April 2019 through 2 May 2019 ; 2019 , Pages 371-375 ; 9781728115085 (ISBN) Annabestani, M ; Mohammadzadeh, H ; Aghassizadeh, A ; Azizmohseni, S ; Fardmanesh, M ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2019
    Abstract
    In most of the microfluidic applications, it is necessary to have a mixed fluid from the beginning, but in microchannels, due to facing with low Reynolds flows, the fluids flow in the channel by the laminar regimes. Hence the mixing process is a challenging problem and researchers are trying to present fast and reliable micromixers. In this paper, using Ionic Polymer-Metal Composites (IPMCs), an active micromixer has been designed. To investigate the appropriateness of IPMC, using experimental and simulation tests, we show that the IPMC actuator is a potential candidate as an active element of microfluidic micromixers  

    NAFAS: non-rigid air flow active sensor, a cost-effective, wearable, and ubiquitous respiratory bio-sensor

    , Article IEEE Sensors Journal ; Volume 21, Issue 7 , 2021 , Pages 9530-9537 ; 1530437X (ISSN) Annabestani, M ; Esmaeili Dokht, P ; Khazaee Nejad, S ; Fardmanesh, M ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2021
    Abstract
    A Non-rigid Air Flow Active Sensor (NAFAS) to detect the respiratory patterns is introduced in this paper. The main part of NAFAS is an ionic electroactive polymer-based ( ${i}$ -EAP) soft sensor. It can accurately detect breathing patterns and has promising features to develop low cost, wearable, and ubiquitous spirometers. Patients with respiratory diseases need to take pulmonary function tests consistently. Hence, it is time-consuming and expensive. To address these problems, NAFAS presents point-of-care testing (POCT) of the respiratory system's function. The proposed ${i}$ -EAP based sensor is a small strip of Ionic Polymer Metal Composite (IPMC) that has been fabricated using a Nafion... 

    A nonlinear feed-forward memory-less model to fast prediction of threshold voltage in junction-less double-gate MOSFETs

    , Article International Journal of Numerical Modelling: Electronic Networks, Devices and Fields ; Volume 34, Issue 1 , 2021 ; 08943370 (ISSN) Annabestani, M ; Nasserian, M ; Hasanzadeh, F ; Taherzadeh Sani, M ; Hassanzadeh, A. R ; Sharif University of Technology
    John Wiley and Sons Ltd  2021
    Abstract
    Decreasing Drain-Induced-Barrier-Lowering (DIBL) is one of the nondesirable short-channel effects, causes the threshold voltage of the transistor to be reduced by increasing the drain voltage. DIBL makes it impossible for engineers to consider VT as a constant, and it is necessary to calculate VT as a function of the drain voltage. Therefore, to consider the DIBL effect in the design of ICs, a large computational burden is imposed on the system, which slows down the simulation process in circuit-level simulators. Accordingly, a Nonlinear Feed-Forward Memory-Less (NFFML) model using the Gram-Schmidt orthogonalization approach is proposed, which calculates the VT of the new generation of... 

    Percolation theory in reservoir engineering

    , Book King, P. R ; Masihi, Mohsen
    World Scientific  2018

    Multiphysics analysis and practical implementation of a soft μ-actuator- based microfluidic micromixer

    , Article Journal of Microelectromechanical Systems ; Volume 29, Issue 2 , 2020 , Pages 268-276 Annabestani, M ; Azizmohseni, S ; Esmaeili Dokht, P ; Bagheri, N ; Aghassizadeh, A ; Fardmanesh, M ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2020
    Abstract
    Electroactive-Polymers (EAPs) are one of the best soft $mu $ -actuators with great biomedical applications. Ionic ones (i-EAPs) have more promising features and have adequate potential for using in the active microfluidic devices. Here, as a case study, we have designed and fabricated a microfluidic micromixer using an i-EAP named Ionic Polymer-Metal Composite (IPMC). In microfluidics, active devices have more functionality but due to their required facilities are less effective for Point of Care Tests (POCTs). In the direction of solving this paradox, we should use some active components that they need minimum facilities. IPMC can be one of these components, hence by integrating the IPMC... 

    Sole versus dual-sourcing under order dependent lead-times and prices [electronic resource]

    , Article Computers And Operations Research, Published in: Elsevier Journals ; Volume 36, Issue 12, December 2009, Pages 3272–3280 Sajjadieh, M. (Mohsen) ; Eshghi, Kourosh ; Sharif University of Technology
    Abstract
    In this paper, we consider a dual-sourcing model with constant demand and stochastic lead times. Two suppliers may be different in terms of purchasing prices and lead-time parameters. The ordering takes place when the inventory level depletes to a reorder level, and the order is split among two suppliers. Unlike previous works in the order splitting literature, the supply lead time between vendor and buyer as well as unit purchasing prices is considered to be order quantity dependent. The proposed model finds out the optimal reorder point, order quantity and splitting proportion, using a solution procedure. Numerical results show that neglecting the relationship between ordering batch size... 

    Human serum protein adsorption onto synthesis nano-hydroxyapatite

    , Article Protein Journal ; Volume 31, Issue 2 , February , 2012 , Pages 150-157 ; 15723887 (ISSN) Mohsen Nia, M ; Massah Bidgoli, M ; Behrashi, M ; Mohsen Nia, A ; Sharif University of Technology
    2012
    Abstract
    Adsorption of human serum proteins (Albumin and total protein) onto high purity synthesis nano-hydroxyapatite (HA), Ca 10(PO 4) 6(OH) 2, has been studied in a wide temperature range by UV-visible spectrophotometer. Adsorption isotherm is basically important to describe how solutes interact with adsorbent, andiscriticalinoptimizing the use of adsorbent. Inthe present study, the experimental results werefitted tothe Langmuir, Freundlich, Temkin and Dubinin-Radushkevich (DR) models to obtain the characteristic parameters of each model and square of the correlation coefficients (R 2). According to the results, the DR isotherm model had the best agreement with the experimental data. The effect of... 

    Effective Permeability of Isotropic Overlapping Sandbodies in 2D Using Percolation Theory

    , M.Sc. Thesis Sharif University of Technology Fatemi, Amin (Author) ; Masihi, Mohsen (Supervisor)
    Abstract
    Permeability is an essential parameter used for reservoir evaluation, simulation and management to optimize oil recovery. The conventional approach to estimate reservoir connectivity, conductivity, sweep efficiency and other critical information for decision-making is to build detailed geological models, which are then upscaled to a coarser grid where flow simulations are run. However, this takes many hours to be carried out even for a single realization practically. In practice, a very small number of realizations are considered and consequently the true uncertainty in the results is very poorly estimated. In this study, a statistical model of isotropic overlying sandbodies is used to... 

    A Metabonomics Study of Samples of Different Diseases: Investigation of Linear and Non-Linear Model by Nuclear Magnetic Resonance

    , Ph.D. Dissertation Sharif University of Technology Fathi, Fariba (Author) ; Tafazzoli, Mohsen (Supervisor)
    Abstract
    Metabonomics is a quantitative measurement of time dependent metabolic interactions for living systems in response to the pathological or genetic variations. NMR spectroscopy has emerged as a key tool for understanding metabolic processes in living systems. In this project, the study of metabolomics was performed as classification and regression on samples of parkinson’s disease, multiple sclerosis disease, celiac disease and crohn’s disease. In classification part, various methods were applied using optimal parameters.classification methods in Parkinson’s disease, multiple sclerosis disease, celiac disease and crohn’s disease were RF, CART, PLS-DA, RF and RF respectively. Based on the... 

    Determination of Parameters Affecting the Linear Seismic Evaluation of Gravity Dams Using Nonlinear Analysis

    , M.Sc. Thesis Sharif University of Technology Monazzam, Arash (Author) ; Ghaemian, Mohsen (Supervisor)
    Abstract
    Gravity dams are solid concrete structures that maintain their stability against design loads from the geometric shape and the mass and strength of the concrete. Because of their critical role in supplying portable and agricultural water and problems which would happen if they broke, it is required to consider their stability and keep them in safe conditions. They should be able to continue their function after a disaster such as earthquake. But most of them are aged dams with some have been built near faults. Indeed, there are some concerns regarding the performance of these dams under the effect of seismic loads. This research deals with performance evaluation of concerete gravity . The... 

    Numerical Analysis of Soil-Nailed Walls in Seismic Condition

    , M.Sc. Thesis Sharif University of Technology Hazeghian, Mohammad (Author) ; Haeri, Mohsen (Supervisor)
    Abstract
    Soil nailing is an in-situ technique of mechanically stabilizing soil masses which has been used in France, Germany, United states, and recently in Iran. A review of literature shows that Soil-Nailed walls have performed well during strong ground motions in comparison with the gravity retaining structures. After the 1989 Loma Prieta earthquake, minor signs of distress or corresponding deformation were found on the Soil-Nailed walls, indicating excellent performance of such structures during moderate and strong shakings. These observations indicate that Soil-Nailed walls have an inherent satisfactory seismic response. This has been attributed to the intrinsic flexibility of the Soil-Nailed... 

    Collapsible Behavior of Gorgan Loess Using Odeometer

    , M.Sc. Thesis Sharif University of Technology Zamani, Atefeh (Author) ; Haeri, Mohsen (Supervisor)
    Abstract
    In nature, there are types of soils that when goinging under stress at constant moisture, or increase of moisture at constant stress, or change of both characters, they show a sudden and high level decrease in their volume. These type of soils are named as Collapsible soils. Iran is one of the countries that at some parts of its land collapsible soils are found. In this research by using of laboratory equipments, the volume change behavior of collapsible loess soils of Gorgan plain (North of Iran) is evaluated under increase of water content and inundation stress. In these experiments, the usual odeometer cell has been used for exploring the behaviour of collapsibility and volume change of... 

    The Effect of Cementation by Lime on Collapsible Soils Behavior Using Suction Controlled Oedometer Device Case Study: Loess of Gorgan

    , M.Sc. Thesis Sharif University of Technology Zabihi, Nina (Author) ; Haeri, Mohsen (Supervisor)
    Abstract
    Collapsible soils such as loess, which are naturally found unsaturated, are kind of problematic soils that undergo sudden and noticeable decrease in volume under increasing stress at constant moisture, increasing moisture at constant stress, or increase in both of them. This kind of soil can be found in some parts of Iran such as plain of Gorgan. To fulfill the main purpose of this study, evaluating the effect of cementation on collapse behavior of loess of Gorgan, some oedometer tests under controlled matric suction were performed on reconstituted samples without and with lime. The lime was added for stabilizing of the collapsible materials and the amount was chosen to be %3 by weight of...