Sharif Digital Repository

Based on the importance of DNA/RNA binding proteins in different cellular processes, finding binding sites of them play crucial role in many applications, like designing drug/vaccine, designing protein, and cancer control. Many studies target this issue and try to improve the prediction accuracy with three strategies: complex neural-network structures, various types of inputs, and ML methods to extract input features. But due to the growing volume of sequences, these methods face serious processing challenges. So, this paper presents KDeep, based on CNN-LSTM and the primary form of DNA/RNA sequences as input. As the key feature improving the prediction accuracy, we propose a new encoding... 

Speech synthesis and its applications have been very attractive recently. The main purpose of this technique is to produce a speech signal with natural characteristics of human speech like prosody and emotion. Among all existing methods for speech synthesis, statistical parametric speech synthesis methods are more promising because ofhigher flexibility in comparison to other methods. One of the applications of speech synthesis is speech to speech translation. In these systems, the generated voice in target language should have the same characteristics as the input voice in source language. The main purpose of this research is to review and evaluate the cross lingual speaker adaptation... 

Surface piercing propellers are particular type of supercavitating propellers that are commonly used for High-speed vessels. Most studies on this type of propellers has been investigating the hydrodynamic forces. But in recent years with increase in SPPs diameter used in vessels, structural analysis of this type of propellers is considered. For this purpose, studies on the stresses exerted on the propeller structures under load is done with the help of Hydro elastic methods. In this type of analysis, structura of propeller is intended to be flexible and Displacements under pressure checked and Tensions resulting from it are studied.
The present Thesis using ANSYS software to analyze a... 

The increasing demand for autonomous vehicles and reliable communication protocols and hardware interfaces, such as CAN bus and USB, underscores the necessity for stable clock sources that maintain a low temperature coefficient (TC) over wide temperature ranges. This demand is particularly emphasized in applications such as wearables, network sensors, downhole devices, WSNs, and IoT, where long-lasting battery life and frequency-stable clock sources over a broad temperature range (e.g. -20 °C to 100 °C) are crucial. Traditionally, variations in frequency caused by temperature have been mitigated by employing off-chip components like crystals or ceramic based oscillators, but this approach... 

Pricing plays an important and essential role in the profit and income of companies. The importance of pricing is not only related to its role in the company's profitability, but it also changes the customer's understanding and loyalty towards the company and can create the company's reputation or destroy it. Determining the right price will increase product sales and increase customer loyalty and create a competitive advantage for the company. One of the most important and influential variables in product pricing is the amount of demand. The main challenge of companies for product pricing is the uncertainty in their demand. In order to deal with this problem, data-driven pricing is used.... 

In this study, electrochemical oxygen reduction reaction (ORR) was studied on Cu, Pd, Rh, Pd-Cu and Rh-Cu alloys in alkaline solution. Pd-Cu and Rh-Cu alloys were prepared by electrochemical methods. On copper electrode it is found that direct oxygen reduction is accompanied by the electrochemical reductions of copper oxides. Also, mechanism and kinetics of reaction change as the amount of copper oxides increase on the surface. For electrodeposited alloys, it is indicated that the reactivity of Pd-Cu and Rh-Cu alloys toward oxygen reduction is higher than pure Pd and pure Rh. The maximum reactivity among Pd-Cu alloys is related to the sample with 24.5% copper content while the maximum... 

Cavity Quantum Electro-Dynamics (CQED) in Weak, Strong and Ultra-Strong coupling Regimes are studied. A MATLAB m-file is written which is able to solve any arbitrary CQED configuration. This program demands input data such as number of Quantum Dots, number of energy levels of each Quantum Dot, energies of each energy level of Quantum Dots, Number of cavity modes, eign-frequency of each cavity mode, coupling constant, dipole strength of each allowed transition of Quantum Dots and initial state of system from user and begins to solve the Schrodinger equation for annihilation and atomic ladder operators. In addition, coefficients of each possible ket will be calculated. Since, any approximation... 

Strongly correlated materials are kind of materials in which novel electric and magnetic properties will appear as a result of strong correlations among their electrons like “heavy fermion materials”. Kondo lattice model is a model to describe heavy fermion materials. If we are merely interested in the magnetic properties of heavy fermions we can replace the Kondo lattice Model with the simpler model called the Kondo-necklace model which consists of the interactions only among the spins of the itinerant (conduction) and localized electrons (magnetic impurities) and also the interactions between the spins of the itinerant electrons. In this thesis we investigate the properties of the one... 

In this study a new Ni(II)-¬oxazoline complex was synthesized by reaction of Ni(CH3COO)2.4H2O and 2-(2׳-hydroxyphenyl)-2-oxazoline ligand in MeOH solvent. The resulting complex bis[2-(2׳-hydroxyphenyl)-2-oxazolinato]Ni(II), was characterized by different spectroscopic methods. X-ray diffraction showed that this complex is four coordinated with a square planner geometry. The complex was applied as an efficient homogeneous catalyst in C-C coupling Heck reaction of arylhalides with olefins such as methylacrylate. Investigation of the catalytic activity of the complex in Heck reaction between arylhalides and olefins showed high yield and selectivity. For example reaction between iodobenzene and... 

Given the complex structure of electronic waste and the difficulty of recycling it by traditional methods, the focus is mainly on biohydrometallurgy method, and in particular on bioleaching. To recover metals, various microorganisms are utilized in this method. In light of previous studies, cyanogenic bacteria have been widely used for the extraction of basic and precious metals. Among the species, indigenous microorganisms have a higher ability to resist toxic environments in the bioleaching of metals due to their adaptation by rapid changes in their metabolic system over time. The main objective of this study is to isolate indigenous microorganisms from electronic waste landfill for their... 

This study investigates the effect of titanium dioxide and magnesium oxide additives on hydroxyapatite synthesized by sol-gel and composite with the predominant phase of hydroxyapatite by in situ method to improve mechanical properties. Scaffold samples were synthesized with nanometer-sized hydroxyapatite and composite powder particles by gel casting and sintered at 1200 ° C. Then, to evaluate the synthesized powders, simultaneous thermal analysis (STA), X-ray diffraction test, FTIR test, FESEM, EDS, and MAP analysis were used. Also, to evaluate the mechanical properties of the scaffolds, a compressive test was used, and to evaluate the scaffolds' density, the Archimedes method was used.... 

Due to the prominence of the evaluation of the consequences of rising temperatures, this paper examines the effects of temperature variation on mortality across different demographic groups in Iran. I use a rich weekly data set from 2009 to 2017 across different demographic groups to understand the potential health impacts of climate change in a developing country. Using several fixed effect regressions, I discover that for an additional day with a mean temperature over 25°C, mortality rate increases by 2.56% relative to the effects of an extra day in 0-5 °C, in the weekly temperature exposure horizon. I test for the harvesting effect by comparing the estimates at weekly and monthly... 

In the current situation and considering the economic conditions, entrepreneurship and self-employment are important factors of business growth. To prepare people in this field, there is a need for effective training that can motivate people. Identifying the effective methods and different dimensions of the entrepreneurship education framework that can lead to setting up a successful program for training people and facilitate the way to achieve the goal of education is one of the important goals of this research. By studying the literature from 2010 onwards, this research systematically examined 96 articles and tried to improve the framework of entrepreneurship education that was stated in... 

Equal Channel angular pressing (ECAP) is one of the most applicable Severe Plastic Deformation (SPD) Procedures which results in improvement of strength and ductility through grain refinement and an appropriate texture development. In this study, in order to achieve a proper orientation and microstructure, ECAP was performed in different routes and temperatures up to 4 passes on AZ31 magnesium alloy. Microstructure and mechanical properties were studied. X-ray diffraction analysis was performed to study the basal orientation variation and calculation of sub-grain size. In addition, cold rolling at room temperature was done on the fourth pass specimens, in order to study the effect of ECAP... 

In this research a no-wait flowshop sequence dependent setup time scheduling problem with weighted earliness-tardiness penalties as the criterion (F_m |nwt,S_ijk |∑▒〖w_j^' E_j+w_j^" T_j 〗) is investigated. It is assumed that n jobs are assigned to a flowshop with m machines. The jobs are not allowed to wait between two successive machines according to no-wait requirement. Moreover each machine needs a setup time before processing a new job. The value of this setup time is dependent on the previous processed job on that machine.
A mixed integer linear programming model is proposed to solve the problem. As the problem is shown to be strongly NP-hard, a particle swarm optimization (PSO)... 

One of the most important issues that an organization faced with is resource management. The proper resource management has the great rule in organization cost reduction. One of the most efficient processes in resource allocation is auction and there is different auction with different mechanism and goals. In an auction there is a set of items and a set of bids, and the task of auctioneer is matching items with suitable bids. Each bid consist of desirable items and the bidder value of that items. In an auction process, after mechanism design of auction and auction implementation we must identify the winners of auction and this is a hard problem even in simple auction.
In this study we... 

In this work, inertial guidance and control of an axisymmetric flying vehicle with a spinning part is performed based on dynamic modeling and seven degree of freedom simulation. Flying vehicle is composed of front and aft bodies and these bodies are connected to each other via a hydrodynamic bearing. Front body is roll isolated from the aft body and includes all necessary guidance and control equipments such as sensors, canard set and so on. The control fins, located on the nose, is used to control the roll angle of the nose and to execute the lateral acceleration commands. Also, the aft body is freely rolling and includes the stabilizing fins. In this project, the translational and...