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Numerical Study of Vascular Shear Stress Effects on Blood Clotting Processes
, M.Sc. Thesis Sharif University of Technology ; Firoozabadi, Bahar (Supervisor)
Abstract
Blood clotting and clot formation in damaged vessels are vital mechanisms of the body. Any disorder in performing this mechanism leads to various problems such as excessive bleeding or, on the contrary, causes vascular occlusion and diseases such as embolism. Due to the importance of this issue, extensive research has been done to understand this phenomenon and the factors affecting it. In this thesis, the effect of shear stress, coagulation factor concentration and wound location in coronary bifurcation on clot formation and growth and its interaction with velocity field is numerically investigated. Blood flow is modeled non-Newtonian with Carreau-Yasuda model. Various chemical species...
Functional Connectivity in Depressive Disorder Using Functional Magnetic
Resonance Imaging Data in Auditory Stimulation Mode
,
M.Sc. Thesis
Sharif University of Technology
;
Fatemizadeh, Emadeddin
(Supervisor)
Abstract
Evidence shows that people with depressive disorder show altered functional connectivity in some of the parts of the brain. The functional characteristics of these brain areas in people with this disorder have not been completely determined. On the other hand, some researchers have rejected the static nature of functional connectivity and stated that functional connectivity changes over time. Measuring brain activity non-invasively with functional magnetic resonance imaging increases our understanding of brain organizations and functional mechanisms, so in this study, we used the functional magnetic resonance imaging data of 18 healthy subjects and 18 subjects with depression. Method: The...
Should fast-food franchisees pursue entrepreneurial orientation?
, Article Entrepreneurship Research Journal ; 2021 ; 21946175 (ISSN) ; Tasavori, M ; Andersen, J ; Sharif University of Technology
De Gruyter Open Ltd
2021
Abstract
Although it is widely accepted that entrepreneurial orientation (EO) improves firm performance, scholars have advised that particular attention should be paid to the context. In this research, we investigate a less explored context of franchising where business systems and procedures are usually dictated to franchisees by franchisors. Therefore, whether a franchisor should allow franchisees to pursue EO (innovativeness, proactiveness, risk-taking, competitive aggressiveness, and autonomy) is not clear. In the context of franchising, the majority of prior studies have mainly focused on the employment of EO as a unidimensional construct and at the franchisor level. In this research, we take a...
Should fast-food franchisees pursue entrepreneurial orientation?
, Article Entrepreneurship Research Journal ; Volume 13, Issue 2 , 2023 , Pages 185-220 ; 21946175 (ISSN) ; Tasavori, M ; Andersén, J ; Sharif University of Technology
De Gruyter Open Ltd
2023
Abstract
Although it is widely accepted that entrepreneurial orientation (EO) improves firm performance, scholars have advised that particular attention should be paid to the context. In this research, we investigate a less explored context of franchising where business systems and procedures are usually dictated to franchisees by franchisors. Therefore, whether a franchisor should allow franchisees to pursue EO (innovativeness, proactiveness, risk-taking, competitive aggressiveness, and autonomy) is not clear. In the context of franchising, the majority of prior studies have mainly focused on the employment of EO as a unidimensional construct and at the franchisor level. In this research, we take a...
An Anonymity Approach Using Cooprerative Security
, M.Sc. Thesis Sharif University of Technology ; Jalili, Rasoul (Supervisor)
Abstract
Providing anonymity in communications is one of the major requirements for the preserving the privacy of users using communication networks. There are several protocols for transmitting anonymous message in public communication networks. DC-Nets can be considered as an important solution to anonymous communications because they provide perfect anonymity; however, their high message and bit complexity is a major obstacle in their practical usage. All DC-Net based protocols provide anonymity of sender and receiver by establishing some anonymous channels for transmission of messages. Each execution of the DC-Net protocol acts as an anonymous channel, which only one participant can send his...
Prevention of gestational diabetes mellitus (GDM) and probiotics: Mechanism of action: A review
, Article Current Diabetes Reviews ; Volume 16, Issue 6 , 2020 , Pages 538-545 ; Bagheri, N ; Mohammad Alizadeh Charandabi, S ; Kashani, N ; Mobaraki Asl, N ; Mirghafurvand, M ; Asgharian, H ; Ansari, F ; Pourjafar, H ; Sharif University of Technology
Bentham Science Publishers
2020
Abstract
Background: Gestational Diabetes Mellitus (GDM) is a health problem that is increasing around the world. Introduction: Prevention of GDM, rather than treatment, could have several benefits in terms of both health and economic cost. Even a slight reduction in maternal glucose in non-diabetic women, particularly in women at high risk for GDM, may have significant benefits for pregnancy results and the future health of off-springs. Probiotics are a relatively new intervention, which are assessed by mothers’ metabolism, and can reduce blood sugar levels, prevent gestational diabetes and reduce the maternal and fetal complications resulting from it. The aim of this study was to review the studies...
Dose-dependent effects of nanoscale graphene oxide on reproduction capability of mammals
, Article Carbon ; Volume 95 , December , 2015 , Pages 309-317 ; 00086223 (ISSN) ; Ghaderi, E ; Hashemi, E ; Akbari, E ; Sharif University of Technology
Elsevier Ltd
2015
Abstract
In vivo dose-dependent effects of nanoscale graphene oxide (NGO) sheets on reproduction capability of Balb/C mice were investigated. Biodistribution study of the NGO sheets (intravenously injected into male mice at dose of ∼2000 μg/mL or 4 mg/kg of body weight) showed a high graphene uptake in testis. Hence, in vivo effects of the NGO sheets on important characteristics of spermatozoa (including their viability, morphology, kinetics, DNA damage and chromosomal aberration) were evaluated. Significant in vivo effects was found at the injected concentrations ≥200 μg/mL after (e.g., ∼45% reduction in sperm viability and motility at 2000 μg/mL). Observation of remarkable DNA fragmentations and...
Accelerated differentiation of neural stem cells into neurons on ginseng-reduced graphene oxide sheets
, Article Carbon ; Volume 66 , January , 2014 , Pages 395-406 ; Ghaderi, E ; Abouei, E ; Hatamie, S ; Ghasemi, E ; Sharif University of Technology
2014
Abstract
Asian red ginseng was used for green reduction of chemically exfoliated graphene oxide (GO) into reduced graphene oxide (rGO). The reduction level and electrical conductivity of the ginseng-rGO sheets were comparable to those of hydrazine-rGO ones. Reduction by ginseng resulted in repairing the sp 2 graphitic structure of the rGO, while hydrazine-rGO showed more defects and/or smaller aromatic domains. The ginseng-rGO sheets presented a better stability against aggregation than the hydrazine-rGO ones in an aqueous suspension. Whilst the hydrophobic hydrazine-rGO films exhibited no toxicity against human neural stem cells (hNSCs), the hydrophilic GO and ginseng-rGO films (as more...
Contested framings and policy controversies: Analysing biosafety policy-making in Iran
, Article Science and Public Policy ; Volume 40, Issue 5 , 2013 , Pages 616-627 ; 03023427 (ISSN) ; Millstone, E ; Sharif University of Technology
2013
Abstract
Vigorous debates have taken place within and between many countries about regulatory policy regimes covering the assessment and approval of genetically modified (GM) crops. In Iran, a very vigorous and hotly contested policy debate concerning legislation covering GM crops occurred between 2004 and 2009, but it was confined within government circles with almost no public discussion. This paper analyses the Iranian policy-making process in the period 2006-9. It explains how and why a stalemate arose in disputes between ministries and departments. The chosen analytical framework draws mainly on the regulation of technological risks and the analysis of public policy-making. It deploys the...
On the possible volumes of μ-way latin trades
, Article Aequationes Mathematicae ; Volume 63, Issue 3 , 2002 , Pages 303-320 ; 00019054 (ISSN) ; Billington, E. J ; Bryant, D. E ; Mahmoodian, E. S ; Sharif University of Technology
Birkhauser Verlag Basel
2002
Abstract
A μ-way latin trade of volume s is a set of μ partial latin rectangles (of inconsequential size) containing exactly the same s filled cells, such that if cell (i, j) is filled, it contains a different entry in each of the μ partial latin rectangles, and such that row i in each of the μ partial latin rectangles contains, set-wise, the same symbols and column j, likewise. In this paper we show that all μ-way latin trades with sufficiently large volumes exist, and state some theorems on the non-existence of μ-way latin trades of certain volumes. We also find the set of possible volumes (that is, the volume spectrum) of μ-way latin trades for μ = 4 and 5. (The case μ = 2 was dealt with by Fu,...
The three-way intersection problem for latin squares
, Article Discrete Mathematics ; Volume 243, Issue 1-3 , 2002 , Pages 1-19 ; 0012365X (ISSN) ; Billington, E. J ; Bryant, D. E ; Mahmoodian, E. S ; Sharif University of Technology
2002
Abstract
The set of integers k for which there exist three latin squares of order n having precisely k cells identical, with their remaining n2 -k cells different in all three latin squares, denoted by I3[n], is determined here for all orders n. In particular, it is shown that I3[n] = {0,.,n2 -15}U [n2 - 12,n2-9,n2], for n ≫8. ©2002 Eisevier Science B.V. All rights reserved
Integration of spatial fuzzy clustering with level set for segmentation of 2-D angiogram
, Article IECBES 2014, Conference Proceedings - 2014 IEEE Conference on Biomedical Engineering and Sciences: "Miri, Where Engineering in Medicine and Biology and Humanity Meet", 8 December 2014 through 10 December 2014 ; December , 2015 , Pages 309-314 ; 9781479940844 (ISBN) ; Zahedi, E ; Fatemizadeh, E ; Sharif University of Technology
Institute of Electrical and Electronics Engineers Inc
2015
Abstract
Coronary angiography is a vital instrument to detect the prevailing of vascular diseases, and accurate vascular segmentation acts a crucial role for proper quantitative analysis of the vascular tree morphological features. Level set methods are popular for segmenting the coronary arteries, but their performance is related to suitable start-up and optimum setting of regulating parameters, essentially done manually. This research presents a novel fuzzy level set procedure with the objective of segmentation of the coronary artery tree in 2-D X-ray angiography as automatically. It is clever to clearly develop from the early segmentation with spatial fuzzy grouping. The adjusting parameters of...
Deep relative attributes
, Article 13th Asian Conference on Computer Vision, ACCV 2016, 20 November 2016 through 24 November 2016 ; Volume 10115 LNCS , 2017 , Pages 118-133 ; 03029743 (ISSN); 9783319541921 (ISBN) ; Noury, E ; Adeli, E ; Sharif University of Technology
Springer Verlag
2017
Abstract
Visual attributes are great means of describing images or scenes, in a way both humans and computers understand. In order to establish a correspondence between images and to be able to compare the strength of each property between images, relative attributes were introduced. However, since their introduction, hand-crafted and engineered features were used to learn increasingly complex models for the problem of relative attributes. This limits the applicability of those methods for more realistic cases. We introduce a deep neural network architecture for the task of relative attribute prediction. A convolutional neural network (ConvNet) is adopted to learn the features by including an...
A public code for astrometric microlensing with contour integration
, Article Monthly Notices of the Royal Astronomical Society ; Volume 505, Issue 1 , 2021 , Pages 126-135 ; 00358711 (ISSN) ; Khalouei, E ; Bachelet, E ; Sharif University of Technology
Oxford University Press
2021
Abstract
We present the first public code for the calculation of the astrometric centroid shift occurring during microlensing events. The computation is based on the contour integration scheme and covers single and binary lensing of finite sources with arbitrary limb darkening profiles. This allows for general detailed investigations of the impact of finite source size in astrometric binary microlensing. The new code is embedded in version 3.0 of vbbinarylensing, which offers a powerful computational tool for extensive studies of microlensing data from current surveys and future space missions. © 2021 The Author(s) Published by Oxford University Press on behalf of Royal Astronomical Society
Toward electrically tunable, lithography-free, ultra-thin color filters covering the whole visible spectrum
, Article Scientific Reports ; Volume 8, Issue 1 , 2018 ; 20452322 (ISSN) ; Serebryannikov, A. E ; Khavasi, A ; Vandenbosch, G. A. E ; Ozbay, E ; Sharif University of Technology
Nature Publishing Group
2018
Abstract
The possibility of real-time tuning of optical devices has attracted a lot of interest over the last decade. At the same time, coming up with simple lithography-free structures has always been a challenge in the design of large-area compatible devices. In this work, we present the concept and the sample design of an electrically tunable, lithography-free, ultra-thin transmission-mode color filter, the spectrum of which continuously covers the whole visible region. A simple Metal-Insulator-Metal (MIM) cavity configuration is used. It is shown that using the electro-optic dielectric material of 4-dimethyl-amino-N-methyl-4-stilbazoliumtosylate (DAST) as the dielectric layer in this...
A novel method for modeling the magnetizing yoke
, Article Electromagnetics ; Volume 30, Issue 3 , 2010 , Pages 297-308 ; 02726343 (ISSN) ; Norouzi, E
2010
Abstract
Magnetic flux leakage is the most widely used method for oil and gas pipeline non destructive testing. The saturation level of the sample under test has a significant effect on its efficiency; therefore, the magnetizing yoke requires an elaborate design. The finite element method is the conventional approach used for this purpose, but it is very time consuming. In this article, a neuro-fuzzy method is presented to model the behavior of the magnetizing yoke. Modeling a few different designs with the finite element method and using the results for training the neuro-fuzzy model eradicates the necessity of modeling a huge number of designs with the finite element method. The acquired...
On decomposing complete tripartite graphs into 5-cycles
, Article Australasian Journal of Combinatorics ; Volume 54, Issue 2 , 2012 , Pages 289-301 ; 10344942 (ISSN) ; Mahmoodian, E. S ; Mollaahmadi, E ; Sharif University of Technology
AJC
2012
Abstract
The problem of finding necessary and sufficient conditions to decompose a complete tripartite graph K(r, s, t) into 5-cycles was first considered by Mahmoodian and Mirzakhani (1995). They stated some necessary conditions and conjectured that these conditions are also sufficient. Since then, many cases of the problem have been solved by various authors; however the case when the partite sets r ≤ s ≤ t have odd and distinct sizes remains open. A necessary condition is t ≤ 3r. Billington and Cavenagh (2011) have shown that when r, s, and t are all odd and r ≤ s ≤ t ≤ κr, where κ ≈ 1.0806, then the conjectured necessary conditions for decomposing are also sufficient. We extend this result...
Ultra-sensitive detection of leukemia by graphene
, Article Nanoscale ; Vol. 6, issue. 24 , Dec , 2014 , p. 14810-14819 ; Ghaderi, E ; Hashemi, E ; Rahighi, R ; Sharif Universit of Technology
2014
Abstract
Graphene oxide nanoplatelets (GONPs) with extremely sharp edges (lateral dimensions ∼20-200 nm and thicknesses <2 nm) were applied in extraction of the overexpressed guanine synthesized in the cytoplasm of leukemia cells. The blood serums containing the extracted guanine were used in differential pulse voltammetry (DPV) with reduced graphene oxide nanowall (rGONW) electrodes to develop fast and ultra-sensitive electrochemical detection of leukemia cells at leukemia fractions (LFs) of ∼10-11 (as the lower detection limit). The stability of the DPV signals obtained by oxidation of the extracted guanine on the rGONWs was studied after 20 cycles. Without the guanine extraction, the DPV peaks...
Specific picomolar detection of a breast cancer biomarker her-2/neu protein in serum: electrocatalytically amplified electroanalysis by the aptamer/peg-modified electrode
, Article ChemElectroChem ; Volume 4, Issue 4 , 2017 , Pages 872-879 ; 21960216 (ISSN) ; Kékedy Nagy, L ; Ferapontova, E. E ; Sharif University of Technology
Wiley-VCH Verlag
2017
Abstract
Specific and sensitive electroanalysis of blood-circulating protein cancer biomarkers is often complicated by interference from serum proteins nonspecifically adsorbing at the biosensing interface and masking specific reactions of interest. Here, we have developed an electrocatalytically amplified assay for specific and sensitive analysis of human epidermal growth factor receptor-2 (HER-2/neu, a protein cancer biomarker over-expressed in breast cancers) that allows us to avoid both the interference from bovine serum albumin (BSA) and electrocatalytic amplification of the signal stemming from the specific aptamer−HER-2/neu binding. A HER-2/neu-specific thiolated aptamer sequence was...
A two layer texture modeling based on curvelet transform and spiculated lesion filters for recognizing architectural distortion in mammograms
, Article Middle East Conference on Biomedical Engineering, MECBME ; 17 - 20 February , 2014 , pp. 21-24 ; Nadjar, H. S ; Fatemizadeh, E ; Mohammadi, E ; Sharif University of Technology
2014
Abstract
This paper presents a two layer texture modeling method to recognize architectural distortion in mammograms. We propose a method that models a Gaussian mixture on the Curvelet coefficients and the outputs of Spiculated Lesion Filters. The Curvelet transform and the Spiculated Lesion Filters have been applied to extract textural features of mammograms in literature. However the key difference between this study and the previous ones is that in our approach, a Gaussian mixture models the textural features extracted by the Curvelet transform and the Spiculated Lesion Filters. The results of the current study are shown in the form of accuracy and the area under the receiver operating...