Sharif Digital Repository

Based on the importance of DNA/RNA binding proteins in different cellular processes, finding binding sites of them play crucial role in many applications, like designing drug/vaccine, designing protein, and cancer control. Many studies target this issue and try to improve the prediction accuracy with three strategies: complex neural-network structures, various types of inputs, and ML methods to extract input features. But due to the growing volume of sequences, these methods face serious processing challenges. So, this paper presents KDeep, based on CNN-LSTM and the primary form of DNA/RNA sequences as input. As the key feature improving the prediction accuracy, we propose a new encoding... 

Speech synthesis and its applications have been very attractive recently. The main purpose of this technique is to produce a speech signal with natural characteristics of human speech like prosody and emotion. Among all existing methods for speech synthesis, statistical parametric speech synthesis methods are more promising because ofhigher flexibility in comparison to other methods. One of the applications of speech synthesis is speech to speech translation. In these systems, the generated voice in target language should have the same characteristics as the input voice in source language. The main purpose of this research is to review and evaluate the cross lingual speaker adaptation... 

Surface piercing propellers are particular type of supercavitating propellers that are commonly used for High-speed vessels. Most studies on this type of propellers has been investigating the hydrodynamic forces. But in recent years with increase in SPPs diameter used in vessels, structural analysis of this type of propellers is considered. For this purpose, studies on the stresses exerted on the propeller structures under load is done with the help of Hydro elastic methods. In this type of analysis, structura of propeller is intended to be flexible and Displacements under pressure checked and Tensions resulting from it are studied.
The present Thesis using ANSYS software to analyze a... 

Pricing plays an important and essential role in the profit and income of companies. The importance of pricing is not only related to its role in the company's profitability, but it also changes the customer's understanding and loyalty towards the company and can create the company's reputation or destroy it. Determining the right price will increase product sales and increase customer loyalty and create a competitive advantage for the company. One of the most important and influential variables in product pricing is the amount of demand. The main challenge of companies for product pricing is the uncertainty in their demand. In order to deal with this problem, data-driven pricing is used.... 

The increasing demand for autonomous vehicles and reliable communication protocols and hardware interfaces, such as CAN bus and USB, underscores the necessity for stable clock sources that maintain a low temperature coefficient (TC) over wide temperature ranges. This demand is particularly emphasized in applications such as wearables, network sensors, downhole devices, WSNs, and IoT, where long-lasting battery life and frequency-stable clock sources over a broad temperature range (e.g. -20 °C to 100 °C) are crucial. Traditionally, variations in frequency caused by temperature have been mitigated by employing off-chip components like crystals or ceramic based oscillators, but this approach... 

Autonomous vehicles, as an integral part of intelligent transportation systems, will play a significant role in the future of transportation services. These vehicles have a high potential to improve road traffic capacity and the efficiency of transportation systems. One type of autonomous vehicle is the connected and autonomous vehicle (CAV), which can communicate with each other, roadside units, traffic control signals, and other infrastructures or devices. This study investigates the impact of autonomous vehicles and connected and autonomous vehicles on the traffic flow of the Tehran-Karaj freeway and vice versa, under various penetration rates and in a mixed traffic environment. In this... 

Tall buildings with lightweight and low damping are vulnerable under wind load. The wind loads stimulate tall buildings in the alongwind and acrosswind direction so the wind loads should be considered in addition to the earthquake loads. Wind tunnel testing is one of the empirical testing that used to study the behavior of tall buildings under wind load besides the simulation of turbulence components of the wind field is one of the issues that have been studied by researchers. In this research we have simulated two models of tall building with different side ratio and we have surveyed wind and earthquake loads in the different loading conditions. The models have been analysis in both time... 

Seismic isolation is a method for seismic-resistant design of structures against earthquake and is one of the important control of structures technologies. Codification and publishing of codes for design of seismic isolation takes place widely since 1980s and this codification has undergone extensive evolutions during its developing process. In this project initially the developing process and fundamentals of codifying regulations of seismic design have been investigated and then the developing process of codifying regulations of seismic isolation in current important international codes like ASCE7-05, Eurocode 8, and Japanese code has also been considered. After considering these two... 

To verify most of the numerical and analytical developments in the structural and earthquake engineering techniques, experimental methods have been considered by many researchers. For instance, numerical simulations in structural health monitoring, structural control and energy dissipation systems need to be verified and compared with experimental results. Consequently, research organizations spend substantial budgets on assessing and updating these experimental methods. Many of these experimental tests are essentially conducted on the benchmark structures with specific technical characteristics; these properties should not be changed after each experiment. Therefore, the tests on these... 

There are many parameters which are utilized to obtain a more reasonable performance for structures under earthquake excitations in seismic provisions. It is well recognized that the main character to design of structures under seismic excitation is probabilistic rather than deterministic; therefore, it should be determined if the probability of structural damages is decreased when such parameters change in design of structures. In this thesis, fragility curves are developed in order to evaluate these parameters. Fragility curves are employed for various probability parameters. These diagrams are utilized to demonstrate when a coefficient or a number of parameters are used to improve...