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Bioelectricity generation enhancement in a dual chamber microbial fuel cell under cathodic enzyme catalyzed dye decolorization
, Article Bioresource Technology ; Volume 102, Issue 12 , June , 2011 , Pages 6761-6765 ; 09608524 (ISSN) ; Kariminia, H. R ; Roshandel, R ; Sharif University of Technology
2011
Abstract
Enzymatic decolorization of reactive blue 221 (RB221) using laccase was investigated in a dual-chamber microbial fuel cell (MFC). Suspended laccase was used in the cathode chamber in the absence of any mediators in order to decolorize RB221 and also improve oxygen reduction reaction in the cathode. Molasses was utilized as low cost and high strength energy source in the anode chamber. The capability of MFC for simultaneous molasses and dye removal was investigated. A decolorization efficiency of 87% was achieved in the cathode chamber and 84% COD removal for molasses was observed in the anode chamber. Laccase could catalyze the removal of RB221 and had positive effect on MFC performance as...
Design and Synthesis of a Drug Delivery System Based on Mesoporous Bioactive Glass
, M.Sc. Thesis Sharif University of Technology ; Abdekhodaie, Mohammad Jafar (Supervisor)
Abstract
The aim of this research is to develop a smart mesoporous bioactive glass-based carrier for targeted drug delivery to cancer cells, particularly bone cancer cells. To achieve this, mesoporous bioactive glass nanoparticles were first synthesized, followed by surface modification with amine groups. To prevent premature drug release before reaching the target tissue and to introduce pH sensitivity, the nanoparticle pores were coated with oxidized hyaluronic acid via Schiff-base bonding with the amine groups on the surface. The use of hyaluronic acid facilitates active targeting of CD44 receptors, which are overexpressed on the surface of cancer cells compared to healthy cells. This process...
Simultaneous decolorization and bioelectricity generation in a dual chamber microbial fuel cell using electropolymerized-enzymatic cathode
, Article Environmental Science and Technology ; Volume 46, Issue 12 , 2012 , Pages 6584-6593 ; 0013936X (ISSN) ; Kariminia, H. R ; Bakhshian, S ; Sharif University of Technology
2012
Abstract
Effect of cathodic enzymatic decolorization of reactive blue 221 (RB221) on the performance of a dual-chamber microbial fuel cell (MFC) was investigated. Immobilized laccase on the surface of a modified graphite electrode was used in the cathode compartment in order to decolorize the azo dye and enhance the oxygen reduction reaction. First, methylene blue which is an electroactive polymer was electropolymerized on the surface of a graphite bar to prepare the modified electrode. Utilization of the modified electrode with no enzyme in the MFC increased the power density up to 57% due to the reduction of internal resistance from 1000 to 750 Ω. Using the electropolymerized-enzymatic cathode...
Electrodeposition of Pt nanostructures and its Application as Glucose Sensor
, Ph.D. Dissertation Sharif University of Technology ; Dolati, Abolghasem (Supervisor) ; Ghorbani, Mohammad (Supervisor)
Abstract
The present work describes sensing application of modified Pt nanostructures towards detection of glucose. Modified Pt nanostructured electrodes were prepared using electrodeposition method such as chronoampermetry and potentiostatic pulse methods. The electrodeposition of Pt nanostructures was first studied by voltammetry and amperommetry techniques and then potentiostatic pulse method has been used to produce the alloyed structures of platinum. In this regard, the first electrode was proposed based on alloyed Pt/Ni nanowire arrays (NWAs) for the non-enzymatic detection of glucose. The Pt/Ni NWAs were prepared by pulse electrodeposition of Pt and Ni within a nano-pore polycarbonate (PC)...
Quantum Estimation of Open Systems Using Extended Cramer-Rao Bounds
, M.Sc. Thesis Sharif University of Technology ; Rezakhani, Ali (Supervisor) ; Alipour, Sahar (Co-Advisor)
Abstract
Any physical system is characterized with some set of quantities or parameters, knowing which, is equivalent to estimation of the system. Evaluating such parameters is usually done using tomography methods. An important question to ask, is how to increase the precision of measurement, being able to do some specific set of physical operations, say, measurement?
this question is more important in parameter estimation in quantum meanical systems. It has been shown that, quantum meanics causes a fundamental limit, on precision of estimating su parameters, escribed by the so called “antum Cramér-Rao bound”.We must note that almost all quantum meanical systems are interacting with the...
this question is more important in parameter estimation in quantum meanical systems. It has been shown that, quantum meanics causes a fundamental limit, on precision of estimating su parameters, escribed by the so called “antum Cramér-Rao bound”.We must note that almost all quantum meanical systems are interacting with the...
A review on impacts of drilling mud disposal on environment and underground water resources in south of Iran
, Article Proceedings of the SPE/IADC Middle East Drilling Technology Conference and Exhibition, 26 October 2009 through 28 October 2009 ; 2009 , Pages 447-454 ; 9781615677450 (ISBN) ; Dashtian, H ; Paiaman Mirzai, A ; Al Anazi, B. D ; Sharif University of Technology
2009
Abstract
In drilling oil wells a system of complex fluids and chemical additives is used. Losses of these fluids in the well during drilling or disposal of them in well site could transfer pollutants to groundwater. In the present study a number of well sites, located in South of Iran, were studied to indicate types and magnitude of various pollutant materials that remain in the environment undestroyed and have considerable impacts on the underground water resources. Hydrocarbons used in Oil Base Muds (OBM) that can't be biodegrade readily in nature found to be the most severe pollutant material caused by disposal of Drilling Mud and Cuttings. Volume of drilling waste for these oil wells evaluated to...
Experimental Investigation of Electricity Generation in Dual Chamber Microbial Fuel Cell- Effective Parameters in Cathode Chamber
, M.Sc. Thesis Sharif University of Technology ; Kariminia, Hamid Reza (Supervisor) ; Roshandel, Ramin (Supervisor)
Abstract
Two major challenges facing countries all around the world are the demand for renewable energy resources and treatment of large quantities of industrial and household wastewaters. One of the new and environmentally acceptable methods to produce green energy is Microbial Fuel Cells (MFCs), which has been noted by many researchers in recent years. MFC is a new technology which has the ability to produce green energy along with treatment of wastewater stream, based on oxidation of organic maters through microbial metabolism. In this study we investigated the effects of different cathode chamber parameters on operation and efficiency of a two chamber MFC at laboratory scale. These parameters...
Selective Transfection of Smart Polymeric Nanoparticles Into Reactive Astrocytes in Animal Model of Spinal Cord Injury
, Ph.D. Dissertation Sharif University of Technology ; Frounchi, Masoud (Supervisor) ; Mashayekhan, Shohreh (Co-Supervisor) ; Kiani, Sahar (Co-Supervisor)
Abstract
In this study, chitosan-based nanoparticles were prepared due to their biocompatibility, availability, high loading capacity of drug, stimulus responsive behavior and the presence of active functional groups. Chitosan was chemically functionalized with reactive oxygen species (ROS)-responsive moiety to respond to the oxidative stess and endosomal pH in nerve injuries. To prepare nanoparticles, functinalized chitosan ionically gelated with pH-responsive polyanions with ROS-scavenging properties such as polyacrylic acid and hyaluronic acid. Then, pH- and ROS-responsive nanoparticles were used for selective transfection into reactive astrocytes and axonal regeneration in spinal cord injuries....
Nanogold imprinted starch bionanocomposites for food packaging applications
, Article Starch Based Nanomaterials for Food Packaging: Perspectives and Future Prospectus ; 2023 , Pages 209-226 ; 978-044318967-8 (ISBN); 978-044318968-5 (ISBN) ; Saleem, I. M ; Sahar, A ; Raza, N ; Sameen, A ; Nayik, G. A ; Ramniwas, S ; Sharif University of Technology
Elsevier
2023
Abstract
Food science researchers are concerned about global food wastage due to decreased shelf life. It has been shown that using approaches based on nanotechnology, including metal-based nanoparticles (NPs), can alleviate the issues with decreased shelf life and environmental problems. Gold nanoparticles (AuNPs) and their synthesis have seen notable advancements in the last several decades. AuNPs are now utilised more often in industrial and medicinal settings. AuNPs are being employed in the nanopackaging industry as a recently adopted technique because of their medicinal and antibacterial properties and their inert and hypoallergenic nature. When employed in the food industry, AuNPs have...
Microfluidic systems for stem cell-based neural tissue engineering
, Article Lab on a Chip - Miniaturisation for Chemistry and Biology ; Volume 16, Issue 14 , 2016 , Pages 2551-2571 ; 14730197 (ISSN) ; Bahrami, S ; Mirshekari, H ; Moosavi Basri, S. M ; Bakhshian Nik, A ; Aref, A. R ; Akbari, M ; Hamblin, M. R ; Sharif University of Technology
Royal Society of Chemistry
2016
Abstract
Neural tissue engineering aims at developing novel approaches for the treatment of diseases of the nervous system, by providing a permissive environment for the growth and differentiation of neural cells. Three-dimensional (3D) cell culture systems provide a closer biomimetic environment, and promote better cell differentiation and improved cell function, than could be achieved by conventional two-dimensional (2D) culture systems. With the recent advances in the discovery and introduction of different types of stem cells for tissue engineering, microfluidic platforms have provided an improved microenvironment for the 3D-culture of stem cells. Microfluidic systems can provide more precise...
Smart drug delivery: Capping strategies for mesoporous silica nanoparticles
, Article Microporous and Mesoporous Materials ; Volume 299 , 2020 ; Zare, H ; Razavi, S ; Mohammadi, H ; Torab Ahmadi, P ; Yazdani, N ; Bayandori, M ; Rabiee, N ; Izadi Mobarakeh, J ; Sharif University of Technology
Elsevier B.V
2020
Abstract
Systematic delivery of therapeutic agents to specific sites, with a stimulus-responsive drug release profile is currently a rapidly growing area. Mesoporous silica nanoparticles (MSNs) are the useful platforms as drug/gene delivery systems due to their unique properties including the ability to control the pore size, high porosity, and morphology, which can directly affect the mechanism and profile of drug release. The appropriate fabrication strategy can tailor the particle shape and size, leading to enhanced delivery and release mechanisms. The MSN surface can be modified by using either organic or inorganic molecules to induce smart and site-specific drug delivery and release....
Nanotechnology in diagnosis and treatment of coronary artery disease
, Article Nanomedicine ; Volume 11, Issue 5 , 2016 , Pages 513-530 ; 17435889 (ISSN) ; Zare, H ; Bakhshian Nik, A ; Yazdani, N ; Hamrang, M ; Mohamed, E ; Sahandi Zangabad, P ; Moosavi Basri, S. M ; Bakhtiari, L ; Hamblin, M. R ; Sharif University of Technology
Future Medicine Ltd
2016
Abstract
Nanotechnology could provide a new complementary approach to treat coronary artery disease (CAD) which is now one of the biggest killers in the Western world. The course of events, which leads to atherosclerosis and CAD, involves many biological factors and cellular disease processes which may be mitigated by therapeutic methods enhanced by nanotechnology. Nanoparticles can provide a variety of delivery systems for cargoes such as drugs and genes that can address many problems within the arteries. In order to improve the performance of current stents, nanotechnology provides different nanomaterial coatings, in addition to controlled-release nanocarriers, to prevent in-stent restenosis....